{"636027":{"#nid":"636027","#data":{"type":"news","title":"James Dahlman Wins Gene Delivery and Gene Editing Focus Group Young Investigator Award","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EJames Dahlman\u003C\/strong\u003E, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, and a researcher in the Petit Institute for Bioengineering and Bioscience at Georgia Tech, received the Gene Delivery and Gene Editing Focus Group (GDGE) Young Investigator Award given by the Controlled Release Society.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThis is his second gene-related new investigator award in 2020 as he previously won the Outstanding New Investigator Award given by the American Society of Gene \u0026amp; Cell Therapy (ASGCT) earlier this year. He is also the recipient of the Outstanding Achievement in Early Career Research 2020 award given by the Georgia Institute of Technology.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDahlman\u0026#39;s laboratory works at the interface of drug delivery and genomics by applying \u0026quot;big data\u0026quot; and \u0026quot;technology development\u0026quot; approaches to nanomedicine. Dahlman and his students have developed DNA barcoded nanoparticles to measure how hundreds of nanoparticles deliver mRNA and siRNA in multiple cell types in vivo, all from a single animal. Since late 2016, the lab has used this approach to quantify more than 4,500 nanoparticles in vivo, thereby identifying nanoparticles that target new cell types without ligands. His lab hopes to apply systems biology approaches to nanomedicine, in order to improve the efficacy of gene therapies and identify genes acting as master regulators of nanoparticle delivery in vivo.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDahlman explained that using DNA barcodes allows researchers to overcome what had been a laborious and time-consuming process. Now hundreds of different nanoparticle types can be tested at once to see which are more effective to safely deliver drugs. His research has spawned the creation of a new company called GuideRX.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EAbout the Gene Delivery and Gene Editing Focus Group in CRS:\u003C\/strong\u003E\u003Cbr \/\u003E\r\nThe Gene Delivery and Gene Editing Focus Group (GDGE) focuses on creating a better fundamental understanding of the barriers of gene delivery and editing, designing improved carriers, and realizing opportunities for therapeutic intervention. Relevant topics include nucleic acid-based approaches for generating therapeutic proteins (e.g. mRNA, pDNA), eliminating disease-causing proteins (e.g. SiRNA, miRNA, ASOs), and precisely editing the genome (e.g. CRISPR\/Cas, TALENs, ZFNs).\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cbr \/\u003E\r\n\u003Cstrong\u003EAbout the Controlled Release Society:\u003C\/strong\u003E\u003Cbr \/\u003E\r\nThe Controlled Release Society (CRS) is a not-for-profit organization devoted to the science and technology of controlled release. The field of controlled release encompasses scientific and technical efforts to regulate the spatial and temporal effects of agents in diverse areas including human and animal health as well as non-pharmaceutical areas.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EMedia Contact:\u003C\/strong\u003E\u003Cbr \/\u003E\r\nWalter Rich\u003Cbr \/\u003E\r\nCommunications Manager\u003Cbr \/\u003E\r\nWallace H. Coulter Department of Biomedical Engineering\u003Cbr \/\u003E\r\nGeorgia Institute of Technology\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Award from the Controlled Release Society was based on his excellent research in genomics and drug delivery"}],"uid":"27513","created_gmt":"2020-06-08 18:02:18","changed_gmt":"2020-06-09 15:07:16","author":"Walter Rich","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2020-06-08T00:00:00-04:00","iso_date":"2020-06-08T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"636026":{"id":"636026","type":"image","title":"James Dahlman, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory","body":null,"created":"1591639252","gmt_created":"2020-06-08 18:00:52","changed":"1591639252","gmt_changed":"2020-06-08 18:00:52","alt":"James Dahlman, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory","file":{"fid":"242016","name":"Web-Dahlman-180416R137-DEV.jpg","image_path":"\/sites\/default\/files\/images\/Web-Dahlman-180416R137-DEV.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/Web-Dahlman-180416R137-DEV.jpg","mime":"image\/jpeg","size":433246,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Web-Dahlman-180416R137-DEV.jpg?itok=hpWyjgIb"}}},"media_ids":["636026"],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"}],"keywords":[{"id":"1612","name":"BME"},{"id":"126571","name":"go-PetitInstitute"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EWalter Rich\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["wrich@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}