{"632248":{"#nid":"632248","#data":{"type":"event","title":"BioE PhD Defense Presentation- Ruxiu Liu","body":[{"value":"\u003Cp\u003ERuxiu Liu\u003Cbr \/\u003E\r\nPhD Defense Presentation \u0026ndash; BioE\u003Cbr \/\u003E\r\nFebruary 24th, 2020, 9:00 AM - Pettit (MiRC) Room 102\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EA. Fatih Sarioglu,\u0026nbsp;Ph.D. (Georgia Institute of Technology - ECE) - Chair\u003C\/p\u003E\r\n\r\n\u003Cp\u003EAlbert B. Frazier, Ph.D. (Georgia Institute of Technology - ECE)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EAndr\u0026eacute;s Garc\u0026iacute;a, Ph.D. (Georgia Institute of Technology - ME)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EOmer Inan, Ph.D. (Georgia Institute of Technology - ECE)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EWilbur Lam, Ph.D. (Georgia Institute of Technology - BMED)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EElectronic Antibody Microarrays for Label-free Immunophenotyping of Cell Populations\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EImmunophenotyping (i.e., identifying cell membrane proteins) is widely used to characterize cell populations in basic research and to diagnose diseases from surface biomarkers in the clinic. This process requires complex instruments such as flow cytometers or fluorescence microscopes, which are typically housed in centralized laboratories. In this work, we present a microfluidic technology that employs a network of integrated electrical sensors to identify cell subpopulations based on their membrane antigens in a quantitative manner. To realize this technology, we developed a scalable electronic sensor network called microfluidic CODES (microfluidic coded orthogonal detection by electrical sensing), which combines code division multiple access (CDMA), a spread spectrum telecommunications technique, with Coulter sensing for the distributed detection of cells at strategic nodes across the microfluidic device from a single electrical output. By integrating the Microfluidic CODES technique with microfluidic cell capture chambers pre-functionalized with antibodies against target antigens, the device achieves all-electronic cell immunophenotyping through combinatorial arrangement of antibody sequences along microfluidic paths. Our technology not only provides an integrated platform for label-free combinatorial immunophenotyping of cell populations against multiple antigen targets, but also is built on frugal hardware well suited for resource limited settings or point-of-care applications.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBioE PhD Proposal Presentation- \u0026quot;Electronic Antibody Microarrays for Label-free Immunophenotyping of Cell Populations\u0026quot; - Ruxiu Liu\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Electronic Antibody Microarrays for Label-free Immunophenotyping of Cell Populations\u0022"}],"uid":"27917","created_gmt":"2020-02-10 16:21:04","changed_gmt":"2020-02-10 16:21:04","author":"Laura Paige","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2020-02-24T09:00:00-05:00","event_time_end":"2020-02-24T11:00:00-05:00","event_time_end_last":"2020-02-24T11:00:00-05:00","gmt_time_start":"2020-02-24 14:00:00","gmt_time_end":"2020-02-24 16:00:00","gmt_time_end_last":"2020-02-24 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"65448","name":"Bioengineering Graduate Program"}],"categories":[],"keywords":[{"id":"172056","name":"go-BioE"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"10377","name":"Career\/Professional development"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003ELaura Paige\u003C\/p\u003E\r\n\r\n\u003Cp\u003E404-385-6655\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}