{"621943":{"#nid":"621943","#data":{"type":"event","title":"PhD Defense by Xiangxi Meng","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EXiangxi Meng\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EBME PhD Defense Presentation\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDate: \u003C\/strong\u003EJune 5,\u0026nbsp;2019\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETime: \u003C\/strong\u003E21:00 EDT\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ELocation: \u003C\/strong\u003EUAW 4235 (GT), Wangkezhen Bldg 907 (PKU)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee members:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EQiushi Ren, PhD (Advisor)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EMay D. Wang, PhD (Co-Advisor)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EWeiqiang Chen, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003EChanghui Li, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003EShuming Nie, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EMultiplexed Molecular Imaging in the Second Near-Infrared Window\u003C\/strong\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe second near-infrared window (NIR-II window) is a certain range of near-infrared light with superior ability to penetrate biological tissues. In this research, the basic imaging properties of the NIR-II imaging were first explored. To enable this, equipment for conducting NIR-II imaging were constructed and corresponding fluorescent materials were prepared. A new technique to monitor the NIR-II fluorescence during the synthetic process of the fluorescent material was developed and applied.\u003C\/p\u003E\r\n\r\n\u003Cp\u003ELiquid phantoms with Intralipid were used as a model system to verify the imaging ability, and the results obtained were verified with a CLARITY experiment. After obtaining such results, new methods to multiplex NIR-II fluorescence imaging and other biomedical procedures were proposed and explored. Taking the advantage of its special penetration ability, NIR-II imaging could be used to investigate the transient process of the first several seconds of the distribution of fluorescent quantum dots administered via tail-vein injection. NIR-II imaging was also used to visualize the intestine structure and bowel movement real-time on nude mice.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe NIR-II imaging was conducted to visualize the process of megavolt X-ray beam radiotherapy. The Cherenkov emission can be observed during megavolt X-ray beam therapies, but most of the energy concentrates in the blue to UV range. With the NIR-II imaging system, the NIR-II part of the Cherenkov emission was visualized. The Cherenkov photon energy was also transferred to the NIR-II range using the NIR-II emission quantum dots. Finally, the Cherenkov emission of the radioisotope Cu-64 was studied.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Multiplexed Molecular Imaging in the Second Near-Infrared Window "}],"uid":"27707","created_gmt":"2019-05-23 19:19:18","changed_gmt":"2019-05-23 19:19:18","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2019-06-05T22:00:00-04:00","event_time_end":"2019-06-06T00:00:00-04:00","event_time_end_last":"2019-06-06T00:00:00-04:00","gmt_time_start":"2019-06-06 02:00:00","gmt_time_end":"2019-06-06 04:00:00","gmt_time_end_last":"2019-06-06 04:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"100811","name":"Phd Defense"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}