{"620496":{"#nid":"620496","#data":{"type":"event","title":"PhD Proposal by Monica Marks","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003ETHE SCHOOL OF MATERIALS SCIENCE AND ENGINEERING\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EGEORGIA INSTITUTE OF TECHNOLOGY\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EUnder the provisions of the regulations for the degree\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDOCTOR OF PHILOSOPHY\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003Eon Monday, April 22, 2019\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003E12:00 PM\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003Ein MRDC 3515\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003Ewill be held the\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDISSERTATION\u0026nbsp;PROPOSAL\u0026nbsp;DEFENSE\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003Efor\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EMonica Marks\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003E\u0026quot;Non-Leaching Antimicrobial Additive for Silicone Systems\u0026quot;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee Members:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EProf. Kyriaki Kalaitzidou, Advisor, ME\u003C\/strong\u003E\u003Cstrong\u003E\/MSE\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EProf. Will Gutekunst, Advisor, CHEM\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EProf. Mary Lynn Realff, MSE\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EProf. Blair Brettmann, MSE\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EProf. Julie Champion, ChBE\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EAbstract\u003C\/strong\u003E:\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EAll non-living material surfaces are colonized by microorganisms. In favorable conditions, these microorganisms proliferate and develop complex surface colonies called biofilms. Biofilms are an essential part of all ecosystems; however, for certain material applications, biofilms can be detrimental to device operation and human health. One such application is the use of silicone rubber for biomedical devices. Silicone rubbers are widely used in biomedical applications due to their elasticity, chemical and thermal resistance and biocompatibility; however, they suffer from biofouling. Commercial methods to make antimicrobial silicone include, silver compounds and nanoparticles and quaternary ammonium cations (QAC) as coatings or additives. Both silver and unbound small molecule QACs leach from the silicone surface. Leaching antimicrobial agents have uncontrolled activity and can bioaccumulate in the body and in the environment. This accumulation can pose many threats, including toxicity to non-target organisms and antimicrobial resistance\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThis proposal addresses the potential the use of a PDMS polymer, chain-end functionalized with QAC dendrimers, as a non-leaching antimicrobial additive in silicone systems. The QAC dendrimers introduce tunable charge density through degree of branching. I hypothesize that the QAC dendrimer chain-ends will surface segregate within the PDMS matrix, by means of an entropically driven process, rendering the surface antimicrobial through the use of an additive.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u0022Non-Leaching Antimicrobial Additive for Silicone Systems\u0022"}],"uid":"27707","created_gmt":"2019-04-16 19:52:43","changed_gmt":"2019-04-16 19:52:43","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2019-04-22T13:00:00-04:00","event_time_end":"2019-04-22T15:00:00-04:00","event_time_end_last":"2019-04-22T15:00:00-04:00","gmt_time_start":"2019-04-22 17:00:00","gmt_time_end":"2019-04-22 19:00:00","gmt_time_end_last":"2019-04-22 19:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}