{"616206":{"#nid":"616206","#data":{"type":"event","title":"From GWAS to Gene: Adventures in C. elegans Quantitative and Evolutionary Genetics","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EErik Andersen, \u003C\/strong\u003E\u003Cstrong\u003EPh.D\u003C\/strong\u003E\u003Cstrong\u003E.\u003Cbr \/\u003E\r\nDepartment of Molecular Biosciences\u003Cbr \/\u003E\r\nNorthwestern University\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EABSTRACT\u003C\/strong\u003E\u003Cbr \/\u003E\r\nMy laboratory studies the genetics and genomics of complex traits using\u0026nbsp;\u003Cem\u003ECaenorhabditis\u0026nbsp;\u003C\/em\u003Enematodes, including the keystone model organism\u0026nbsp;\u003Cem\u003EC. elegans\u003C\/em\u003E. I will discuss our recent progress on the characterization of genetic variation across the\u0026nbsp;\u003Cem\u003EC. elegans\u0026nbsp;\u003C\/em\u003Especies with some new collections from the Hawaiian Islands. We see that population diversity is high in this location as compared to the rest of the world. This genetic variation resource can be leveraged for genome-wide association mappings. I will present our high-throughput fitness assays that measure growth and offspring production after exposures to diverse chemicals and toxins. We discovered and characterized natural variation in response to the metalloid arsenic, identifying a new metabolic effect of this toxin. Lastly, I will present data about how\u0026nbsp;\u003Cem\u003EC. elegans\u0026nbsp;\u003C\/em\u003Edisperses in the wild and natural variation in dispersal strategies with implications for niche preferences.\u003C\/p\u003E\r\n\r\n\u003Cdiv\u003EHost: Patrick McGrath, Ph.D.\u003C\/div\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"A Biological Sciences Seminar by Erik Andersen, Ph.D."}],"uid":"27964","created_gmt":"2019-01-10 17:43:29","changed_gmt":"2019-01-10 17:43:59","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2019-03-07T10:55:00-05:00","event_time_end":"2019-03-07T10:55:00-05:00","event_time_end_last":"2019-03-07T10:55:00-05:00","gmt_time_start":"2019-03-07 15:55:00","gmt_time_end":"2019-03-07 15:55:00","gmt_time_end_last":"2019-03-07 15:55:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"180142","name":"Erik Andersen"},{"id":"71271","name":"Patrick McGrath"},{"id":"166892","name":"School of Biological Sciences Seminar"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jasmine.martin@biosci.gatech.edu\u0022\u003EJasmine Martin\u003C\/a\u003E\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}