{"612802":{"#nid":"612802","#data":{"type":"event","title":"PhD Defense by Diego Dumani","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EDiego Dumani\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EBME PhD Defense Presentation\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDate: \u003C\/strong\u003EFriday, November 2nd, 2018\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETime: \u003C\/strong\u003E2 pm\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ELocation:\u003C\/strong\u003E IBB 1128 (Suddath room)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee members:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EStanislav Emelianov, PhD (Advisor)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EFrancisco Robles, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003EBrooks Lindsey, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003ELily Yang, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003EBaowei Fei, PhD\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETitle:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ENanoparticle-Mediated Functional and Molecular Photoacoustic Imaging for Assessment of Metastatic Lymph Nodes\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDespite advances in prevention, detection, and treatment of cancer, this disease remains the second leading cause of death in the United States. The majority of cancer related deaths are due to metastasis rather than primary tumors and, although mortality rates have decreased over the last two decades, efforts to achieve comprehensive diagnoses and effective treatments still encounter obstacles due to lack of technology or excessive morbidity. The goal of this project is to design a non\u2011invasive approach for the assessment of sentinel lymph node metastasis using ultrasound and photoacoustic imaging, augmented with contrast agents. The focus is two-fold: first, it evaluates contrast\u2011enhanced ultrasound and photoacoustic imaging to track functional and molecular changes of metastatic lymph nodes in relevant in vivo cancer models. Specifically, imaging of immune cell uptake and transport of lymphotropic nanoparticles to the sentinel lymph node, and imaging of clearable nanoparticles targeted to the epidermal growth factor receptor provide diagnostic information regarding metastatic nodal involvement. Then, it includes the design of contrast agents to solve challenges of the proposed techniques and augment therapeutic capabilities. Overall, the study is expected to help identify cancer based on functional and molecular changes, therefore augmenting and potentially replacing sentinel lymph node biopsy.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Nanoparticle-Mediated Functional and Molecular Photoacoustic Imaging for Assessment of Metastatic Lymph Nodes"}],"uid":"27707","created_gmt":"2018-10-16 14:24:23","changed_gmt":"2018-10-16 14:24:23","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2018-11-02T15:00:00-04:00","event_time_end":"2018-11-02T17:00:00-04:00","event_time_end_last":"2018-11-02T17:00:00-04:00","gmt_time_start":"2018-11-02 19:00:00","gmt_time_end":"2018-11-02 21:00:00","gmt_time_end_last":"2018-11-02 21:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"100811","name":"Phd Defense"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}