{"612090":{"#nid":"612090","#data":{"type":"news","title":"Jia Lab Collaborating on Genome Imaging","body":[{"value":"\u003Cp\u003EShu Jia, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, is part of a team of researchers from three different institutions utilizing a National Science Foundation (NSF) grant to focus on human cardiac opto-epigenetics.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EJia and his collaborators from George Washington University and Massachusetts General Hospital are recipients of a $2 million, four-year award from the NSF\u0026rsquo;s Emerging Frontiers in Research and Innovation (EFRI), for Chromatin and Epigenetic Engineering.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe research team will develop a new framework and technology for linking epigenetic modulation to phenotype (epigenetics is the study of the biological mechanisms that switch genes on and off). The team is proposing development of new integrated imaging system for super-resolution imaging.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026ldquo;Documenting the sequence of events triggered by the epigenetic master-regulators of cell function has a broader impact for the fundamental understanding of biological function,\u0026rdquo; Jia says, \u0026ldquo;No such technology has been developed to date to link genome re-arrangement to phenotypic signatures in live cells upon an opto-epigenetic trigger.\u0026rdquo;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe team expects its approach to provide a powerful way to probe chromatin-mediated control of transcription in real time, and generate fundamentally new information currently not available through chromatin mapping.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Ca href=\u0022https:\/\/sites.google.com\/site\/thejialab\/members\u0022\u003EThe Jia lab\u003C\/a\u003E has made its reputation working on super-resolution optical microscopy, developing and applying advanced biophotonic tools to study complex, dynamic biological systems at the nanometer scale. The team\u0026rsquo;s research aims to invent a host of methods that enable the extraction of structural, molecular and functional information from intact tissues and organisms.\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe EFRI program provides support of fundamental discovery at the frontiers of engineering research and education, investing in transformative opportunities potentially leading to new areas for fundamental or applied research; new industries or capabilities that result in a leadership position for the country; and\/or significant progress on a recognized national need or grand challenge.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Coulter Department assistant professor teaming with two other institutions on $2 million, four-year project supported by NSF"}],"field_summary":[{"value":"\u003Cp\u003ECoulter Department assistant professor teaming with two other institutions on $2 million, four-year project supported by NSF\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"Coulter Department assistant professor teaming with two other institutions on $2 million, four-year project supported by NSF"}],"uid":"28153","created_gmt":"2018-09-28 21:15:40","changed_gmt":"2018-09-28 21:15:40","author":"Jerry Grillo","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2018-09-28T00:00:00-04:00","iso_date":"2018-09-28T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"612089":{"id":"612089","type":"image","title":"Shu Jia","body":null,"created":"1538169112","gmt_created":"2018-09-28 21:11:52","changed":"1596227396","gmt_changed":"2020-07-31 20:29:56","alt":"","file":{"fid":"233011","name":"shu jia.JPG","image_path":"\/sites\/default\/files\/images\/shu%20jia.JPG","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/shu%20jia.JPG","mime":"image\/jpeg","size":441773,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/shu%20jia.JPG?itok=hGq61JUY"}}},"media_ids":["612089"],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"1612","name":"BME"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jerry.grillo@ibb.gatech.edu\u0022\u003EJerry Grillo\u003C\/a\u003E\u003Cbr \/\u003E\r\nCommunications Officer II\u003Cbr \/\u003E\r\nParker H. Petit Institute for\u003Cbr \/\u003E\r\nBioengineering and Bioscience\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["Jerry.grillo@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}