{"61161":{"#nid":"61161","#data":{"type":"event","title":"Bruce Berne, Columbia University, \u0022Hydrophobicity on small and large length scales\u0022","body":[{"value":"\u003Cp\u003EDr. Jeffrey\nSkolnick and the Center for the Study of Systems Biology are pleased to host\nDistinguished Lecture Series in Systems Biology speaker \u003Cstrong\u003EDr. Bruce Berne \u003C\/strong\u003Efrom\u003Cstrong\u003E Columbia University\u003C\/strong\u003E. His seminar will be held\non Tuesday, October 12, 2010 from 11:00 AM to 12:00 PM in the Klaus Advanced\nComputing Building (Klaus), Room 1116E. The title of his talk will be \u003Cstrong\u003E\u201cH\u003C\/strong\u003E\u003Cstrong\u003Eydrophobicity\non small and large length scales\u003C\/strong\u003E\u003Cstrong\u003E\u0022\u003C\/strong\u003E.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E Hydrophobicity manifests itself differently on large\n and small and length scales in physical and biomoleclar systems. We \ndiscuss the role of  different length scale effects  in protein folding \nand unfolding, the denaturing action of urea, and ligand binding to \nproteins.\n        \u003C\/p\u003E\n    \n            \n        \n\n\n      \u003Cp\u003E\u003Cstrong\u003EAdditional Information:\u003C\/strong\u003E Dr. Berne\u0027s lab\u0027s research focuses on \nunderstanding structural and dynamical processes in condensed matter and\n biophysical systems. Because they study many-body systems, it is \nnecessary to utilize the powerful analytical methods of equilibrium and \ntime-dependent quantum statistical mechanics as well as state-of-the art\n computer simulation methods such as molecular dynamics and quantum \nMonte-Carlo techniques. One important aspect of their research is the \ninvention of new simulation. Recent work along these lines is their \ninvention of a novel multiple time scale method in molecular dynamics \nand its application to the simulation of biomacromolecules, \nhydrophobicity, the detailed mechanism of chemical denaturation, and the\n effect of force on proteins. Another important activity involves the \ninvention of new dynamical fluctuating charge force fields for complex \nmolecular assemblies. \u003C\/p\u003E\u003Cp\u003ECSSB\nDistinguished Lecture Series: Fall 2010\u003Cbr \/\u003E10\/12\/2010 - Bruce Berne, Columbia University\u003Cbr \/\u003E10\/26\/2010 - Gary Siuzdak, The Scripps Research Institute\u003Cbr \/\u003E\n11\/09\/2010 - Charles Cantor, Boston University\u003Cbr \/\u003E\n11\/11\/2010 - Kristin Brown, GlaxoSmithKline\u003Cbr \/\u003E\n11\/30\/2010 - JoAnne Stubbe, MIT\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":"","uid":"27199","created_gmt":"2010-09-22 17:10:37","changed_gmt":"2016-10-08 01:52:22","author":"Jessica Forness","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2010-10-12T12:00:00-04:00","event_time_end":"2010-10-12T13:00:00-04:00","event_time_end_last":"2010-10-12T13:00:00-04:00","gmt_time_start":"2010-10-12 16:00:00","gmt_time_end":"2010-10-12 17:00:00","gmt_time_end_last":"2010-10-12 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":["free_food"],"groups":[{"id":"1182","name":"General"},{"id":"1275","name":"School of Biological Sciences"},{"id":"1278","name":"College of Sciences"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EJessica Gilmore Forness\u003Cbr \/\u003E\nCenter Manager\u003Cbr \/\u003E\nCenter for the Study of Systems Biology\u003Cbr \/\u003E\nPhone: (404) 407-8976 \u003Cbr \/\u003E\nE-mail: \u003Ca href=\u0022mailto:jessica.gilmore@biology.gatech.edu\u0022\u003Ejessica.gilmore@biology.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E\n\u003Ca href=\u0022http:\/\/cssb.biology.gatech.edu\/\u0022 title=\u0022http:\/\/cssb.biology.gatech.edu\/\u0022\u003Ehttp:\/\/cssb.biology.gatech.edu\/\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}