{"690318":{"#nid":"690318","#data":{"type":"news","title":"Accelerating Discovery With AI ","body":[{"value":"\u003Cp\u003EScientific discovery is often portrayed as the result of long hours alone in a lab, but true science is inherently collaborative. The most robust experimental processes are developed through partnerships across multiple areas of research. The need for specialized, multidisciplinary teams slows experiment design, execution, data analysis, and process updates, delaying technological validation and deployment. But if the increasingly automated tools scientists already use in the lab could contribute to this team process of experimental design, the timeline for these goals could be greatly accelerated.\u003C\/p\u003E\u003Cp\u003EThis concept of \u201clab tool as lab assistant\u201d is the premise of a recent paper in \u003Cem\u003Enpj | Computational Materials\u003C\/em\u003E titled \u201cThinking Microscopes: Agentic AI and the Future of Electron Microscopy,\u201d by Vida Jamali, assistant professor the School of Chemical and Biomolecular Engineering; Amirali Aghazadeh, assistant professor in the School of Electrical and Computer Engineering; and Josh Kacher, associate professor in the School of Materials Science and Engineering.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EIn the paper, the team introduces the concept of \u201cthinking electron microscopes,\u201d in which agentic AI systems are directly integrated with the instrument. This allows microscopes to move beyond their conventional role as characterization tools and toward functioning as co-scientists for human users.\u003C\/p\u003E\u003Cp\u003EDrawing on advances in specialized large language models, or LLMs, that demonstrate their ability to collaborate, reason over data, and integrate prior knowledge, the team envisions specialized LLM-based agents assigned to specific roles and areas of knowledge expertise. By explicitly incorporating domain knowledge into specialized agents and distributing information across multiple agents with focused expertise, the approach enables parallel evaluation of competing hypotheses, clearer separation of roles \u2014\u0026nbsp;such as planning, simulation, and critique \u2014 and more transparent and robust reasoning.\u003C\/p\u003E\u003Cp\u003EWithin the experimental pipeline, these agents can analyze materials\u2019 properties, physical data, chemical processes, and other relevant parameters. They could also collaborate with an agent that specializes in experimental design, refining iterative closed-loop experimentation, and real-time scientific discovery.\u003C\/p\u003E\u003Cp\u003EAlthough the research focuses on AI collaboration, the team notes that human researchers must retain accountability for the accuracy and integrity of both the experimental process and the results reported. This oversight begins with advocating for greater open access to research materials in all formats, building community-driven data repositories, and adopting standardization in how experimental parameters and metadata are reported. Equally important, researchers should be willing to report data from failed experiments as well as successful outcomes. Finally, organizations should work together to standardize secure APIs that enable shared, remote access to infrastructure across distances.\u003C\/p\u003E\u003Cblockquote\u003E\u003Cp\u003EWe see this as a step toward scientific instruments that do more than acquire data; systems that can reason over experiments, adapt measurements, and participate in the scientific discovery process alongside researchers. - Vida Jamali,\u0026nbsp;assistant professor the School of Chemical and Biomolecular Engineering\u003C\/p\u003E\u003C\/blockquote\u003E\u003Cp\u003EThe team is already developing these systems by connecting cloud-based, agentic infrastructures to microscopes at the\u0026nbsp;\u003Ca href=\u0022http:\/\/matter-systems.gatech.edu\/\u0022\u003EInstitute for Matter and Systems at Georgia Tech\u003C\/a\u003E. With the addition of agentic AI, the goal is to accelerate discovery and engineering of new nanoscale materials for energy and quantum applications, as well as advance capabilities in cryo-electron microscopy and structural biology. These tools can optimize data collection, link real-time microscope observations with structural models of proteins, and dynamically adjust and prioritize experiments. The team sees this work as the first step toward the next generation of \u201cthinking\u201d electron microscopes, as well as an advancement in scientific discovery across domains.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;- Christa M. Ernst\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EThis research is supported by the Institute for Data Engineering and Science and the Institute for Matter and Systems\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EOriginal Publication\u003C\/strong\u003E\u003Cbr\u003EJamali, V., Aghazadeh, A. \u0026amp; Kacher, J.\u0026nbsp;\u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41524-026-02077-y\u0022\u003EThinking microscopes: agentic AI and the future of electron microscopy.\u003C\/a\u003E \u003Cem\u003Enpj Computational Materials\u003C\/em\u003E 12, 149 (2026). https:\/\/doi.org\/10.1038\/s41524-026-02077-y\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":[{"value":"Automating Electron Microscopy Experimental Design With Agentic AI"}],"field_summary":[{"value":"\u003Cp\u003EScientific discovery is often portrayed as the result of long hours alone in a lab, but true science is inherently collaborative. The most robust experimental processes are developed through partnerships across multiple areas of research.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"New paper teams AI agents with microscopy tools to increase productivity in research processes."}],"uid":"27863","created_gmt":"2026-05-18 13:04:05","changed_gmt":"2026-05-18 19:16:22","author":"Christa Ernst","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2026-05-18T00:00:00-04:00","iso_date":"2026-05-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"680296":{"id":"680296","type":"image","title":"Accelerating-Mats-Discovery-with-AI-Main-Pic-Amelia-N.jpg","body":"\u003Cp\u003EA photo of Vida Jamali, assistant professor the School of Chemical and Biomolecular Engineering; Amirali Aghazadeh, assistant professor in the School of Electrical and Computer Engineering; and Josh Kacher, associate professor in the School of Materials Science and Engineering standing in front of a TEM at Georgia Tech.\u003C\/p\u003E","created":"1779109455","gmt_created":"2026-05-18 13:04:15","changed":"1779109455","gmt_changed":"2026-05-18 13:04:15","alt":"Vida Jamali, assistant professor the School of Chemical and Biomolecular Engineering; Amirali Aghazadeh, assistant professor in the School of Electrical and Computer Engineering; and Josh Kacher, associate professor in the School of Materials Science and Engineering.  Photo courtesy of Amelia Neumeister; Georgia Institute of Technology","file":{"fid":"264543","name":"Accelerating-Mats-Discovery-with-AI-Main-Pic-Amelia-N.jpg","image_path":"\/sites\/default\/files\/2026\/05\/18\/Accelerating-Mats-Discovery-with-AI-Main-Pic-Amelia-N.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2026\/05\/18\/Accelerating-Mats-Discovery-with-AI-Main-Pic-Amelia-N.jpg","mime":"image\/jpeg","size":4622660,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2026\/05\/18\/Accelerating-Mats-Discovery-with-AI-Main-Pic-Amelia-N.jpg?itok=gH8M9NAb"}}},"media_ids":["680296"],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"660369","name":"Matter and Systems"}],"categories":[{"id":"194606","name":"Artificial Intelligence"},{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"},{"id":"135","name":"Research"}],"keywords":[{"id":"187023","name":"go-data"},{"id":"194241","name":"Institute for Matter and Systems"},{"id":"192863","name":"go-ai"},{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"193655","name":"Artificial Intelligence at Georgia Tech"},{"id":"39431","name":"Data Engineering and Science"},{"id":"39471","name":"Materials"},{"id":"193652","name":"Matter and Systems"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cdiv\u003E\u003Cstrong\u003EChrista M. Ernst - \u003C\/strong\u003EResearch Communications Program Manager | Klaus Advance Computing Building 1120E | 266 Ferst Drive | Atlanta GA | 30332 | christa.ernst@research.gatech.edu\u003C\/div\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"687406":{"#nid":"687406","#data":{"type":"news","title":"Apple Vision Pro Powers New Wave of Immersive Education","body":[{"value":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003ELearning electrical and computer engineering has always come with a unique challenge: many of its foundational concepts \u2014 electric fields, magnetic forces, semiconductor behavior \u2014 are invisible to the naked eye and difficult to visualize.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ETo make these invisible principles tangible, students in the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ESchool of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E have long used specialized tools and software. Circuit simulators model voltage and current, electromagnetic tools visualize fields, and semiconductor design platforms reveal transistor behavior. These tools turn abstract theory into interactive experiences that prepare students for real-world engineering challenges.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003ENow, Apple Vision Pro is joining this ecosystem.\u003C\/p\u003E\u003Cp\u003EThe technology introduces spatial computing to learning environments, blending digital content with the physical world.\u003C\/p\u003E\u003Cp\u003EAt the \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/\u0022\u003E\u003Cstrong\u003EInstitute for Matter and Systems\u003C\/strong\u003E\u003C\/a\u003E, infrastructure lead \u003Ca href=\u0022https:\/\/research.gatech.edu\/people\/alex-gallmon\u0022\u003E\u003Cstrong\u003EAlex Gallmon\u003C\/strong\u003E\u003C\/a\u003E, is collaborating with students and industry partners to create immersive digital twins\u2014virtual models that replicate real-world systems\u2014of semiconductor cleanroom equipment.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cThese machines are complex and costly, with parts that can run tens of thousands of dollars,\u201d he said. \u201cEven minor mistakes during operation can lead to expensive damage or downtime.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EGallmon\u0027s team built a virtual replica of a cleanroom vacuum training system. The project serves as a prototype for a workforce development program aimed at high school and college students interested in careers in the semiconductor or vacuum technology fields.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/ece.gatech.edu\/news\/2026\/01\/apple-vision-pro-powers-new-wave-immersive-education\u0022\u003ERead the full story from the School of Electrical and Computer Engineering\u003C\/a\u003E\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003ESpatial computing is transforming engineering education at Georgia Tech and opening new paths for entrepreneurship and technical training.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Spatial computing is transforming engineering education at Georgia Tech and opening new paths for entrepreneurship and technical training."}],"uid":"35272","created_gmt":"2026-01-16 22:13:30","changed_gmt":"2026-02-03 18:39:06","author":"aneumeister3","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2026-01-12T00:00:00-05:00","iso_date":"2026-01-12T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"679037":{"id":"679037","type":"image","title":"Apple-VR-Headset-002.jpeg","body":"\u003Cp\u003EGeorgia Tech student Yash Rajgure using an Apple Vision Pro headset device to demo his team\u0027s project in ECE 6001 Technology Entrepreneurship: Teaming, Ideation, and Entrepreneurship. \u003Cem\u003EPhoto: Allison Carter, Georgia Tech\u003C\/em\u003E\u003C\/p\u003E","created":"1768601620","gmt_created":"2026-01-16 22:13:40","changed":"1768601620","gmt_changed":"2026-01-16 22:13:40","alt":"Georgia Tech student Yash Rajgure using an Apple Vision Pro headset device to demo his team\u0027s project.","file":{"fid":"263148","name":"Apple-VR-Headset-002.jpeg","image_path":"\/sites\/default\/files\/2026\/01\/16\/Apple-VR-Headset-002.jpeg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2026\/01\/16\/Apple-VR-Headset-002.jpeg","mime":"image\/jpeg","size":247313,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2026\/01\/16\/Apple-VR-Headset-002.jpeg?itok=hvEeDIm3"}},"679038":{"id":"679038","type":"image","title":"Gammon-Vision-Pro_1.jpeg","body":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EGallmon showing how Apple Vision Pro can be utilized to train students and workers on sensitive and expensive technical equipment, in this case a cleanroom vacuum system.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","created":"1768601620","gmt_created":"2026-01-16 22:13:40","changed":"1768601620","gmt_changed":"2026-01-16 22:13:40","alt":"Alex Gallmon showing how Apple Vision Pro can be utilized","file":{"fid":"263149","name":"Gammon-Vision-Pro_1.jpeg","image_path":"\/sites\/default\/files\/2026\/01\/16\/Gammon-Vision-Pro_1.jpeg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2026\/01\/16\/Gammon-Vision-Pro_1.jpeg","mime":"image\/jpeg","size":394335,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2026\/01\/16\/Gammon-Vision-Pro_1.jpeg?itok=kxtirBGt"}}},"media_ids":["679037","679038"],"groups":[{"id":"660369","name":"Matter and Systems"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"153","name":"Computer Science\/Information Technology and Security"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"194612","name":"Workforce Development"}],"keywords":[{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"193652","name":"Matter and Systems"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:dwatson@ece.gatech.edu\u0022\u003EDan Watson \u003C\/a\u003E| School of Electrical and Computer Engineering\u003C\/p\u003E","format":"limited_html"}],"email":["dwatson@ece.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"686866":{"#nid":"686866","#data":{"type":"news","title":"Divan, Raychowdhury Named National Academy of Inventors Fellows","body":[{"value":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EThe \u003Ca href=\u0022https:\/\/academyofinventors.org\/\u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003ENational Academy of Inventors\u003C\/strong\u003E\u003C\/a\u003E is honoring two Georgia Tech faculty members for their contributions to technology and society: \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/deepakraj-m-divan\u0022\u003E\u003Cstrong\u003EDeepakraj \u201cDeepak\u201d Divan\u003C\/strong\u003E\u003C\/a\u003E and \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/arijit-raychowdhury\u0022\u003E\u003Cstrong\u003EArijit Raychowdhury\u003C\/strong\u003E\u003C\/a\u003E. Both are in the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ESchool of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ERaychowdhury is a semiconductor pioneer whose patented circuit and system-on-chip designs have advanced computing efficiency and commercialization. Divan is a global leader in power electronics and grid modernization, whose innovations and ventures have transformed how electricity is delivered and managed worldwide.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cCongratulations to Deepakraj and Arijit on earning one of the most esteemed accolades in technology and discovery. Their groundbreaking work, with nearly 100 patents between them, advances solutions to global challenges,\u201d said \u003Ca href=\u0022https:\/\/research.gatech.edu\/raghupathy-sivakumar\u0022\u003ERaghupathy \u201cSiva\u201d Sivakumar\u003C\/a\u003E, chief commercialization officer at Georgia Tech. \u201cTheir success exemplifies how research commercialization drives real-world impact, and we\u2019re proud to see them honored as academy fellows.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EElection to NAI is the highest professional distinction specifically awarded to inventors. With this recognition, Georgia Tech\u2019s roster of NAI Fellows grows to 24. Divan and Raychowdhury join a \u003Ca href=\u0022https:\/\/academyofinventors.org\/wp-content\/uploads\/2025\/12\/2025-Fellows-List.pdf\u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003E2025 class of 169 new fellows\u003C\/strong\u003E\u003C\/a\u003E representing university, government, and nonprofit organizations worldwide. They will be inducted at the NAI 15th Annual Conference on June 4, 2026, in Los Angeles.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Ch3\u003E\u003Cstrong\u003EDeepakraj\u202f\u201cDeepak\u201d Divan\u003C\/strong\u003E\u003C\/h3\u003E\u003Cp\u003EProfessor Emeritus (2004-2025)\u0026nbsp;\u003Cbr\u003EGeorgia Research Alliance Eminent Scholar\u0026nbsp;\u003Cbr\u003E\u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ESchool of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E\u0026nbsp;\u003Cbr\u003EFounder, \u003Ca href=\u0022https:\/\/cde.gatech.edu\/\u0022\u003E\u003Cstrong\u003EGeorgia Tech Center for Distributed Energy\u003C\/strong\u003E\u003C\/a\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EDeepakraj\u202f\u201cDeepak\u201d Divan is a globally recognized innovator in power electronics and grid transformation. He was awarded the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/news\/2023\/12\/divan-selected-ieee-medal-power-engineering-recipient\u0022\u003E\u003Cstrong\u003EIEEE Medal in\u202fPower Engineering\u003C\/strong\u003E\u003C\/a\u003E in 2024.\u003C\/p\u003E\u003Cp\u003EHe holds over 85 U.S. and international patents and has authored 400 refereed publications. His pioneering work on soft\u2011switching converters\u2014integral for efficient energy storage, EV charging, and industrial controls\u2014has spurred a global $70\u202fbillion power electronics industry.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EDivan laid the groundwork for grid\u2011forming inverter control, enabling high-renewables integration. He is the co-author of \u003Ca href=\u0022https:\/\/energy-2040.com\/\u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003EEnergy 2040: Aligning Innovation, Economics and Decarbonization\u003C\/strong\u003E\u003C\/a\u003E, named by Forbes as one of the \u003Ca href=\u0022https:\/\/www.forbes.com\/sites\/globalcitizen\/2024\/12\/28\/10-essential-books-and-podcasts-every-leader-needs-in-2025\/\u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003E\u201c10 Essential Books and Podcasts Every Leader Needs in 2025\u201d\u003C\/strong\u003E\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cBeing named an NAI Fellow is a tremendous honor,\u201d said Divan. \u201cIt reflects years of effort to rethink how electricity is delivered and managed to solve real problems and to drive practical innovations that matter.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;As the founder of Georgia Tech\u2019s Center for Distributed Energy, he led research that transforms electricity delivery through analytics, monitoring, and optimization.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EAn entrepreneur, Divan co-founded Varentec (backed by Bill Gates and Khosla Ventures) and seeded ventures including GridBlock, Soft Switching Technologies, Innovolt, and Smart Wires\u2014raising over $500\u202fmillion. A National Academy of Engineering member and IEEE Fellow, he champions scalable energy-access solutions worldwide.\u003C\/p\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Ch3\u003E\u003Cstrong\u003EArijit Raychowdhury\u003C\/strong\u003E\u003C\/h3\u003E\u003Cp\u003EProfessor and Steve W. Chaddick School Chair\u0026nbsp;\u003Cbr\u003E\u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ESchool of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E\u0026nbsp;\u003Cbr\u003EDirector, \u003Ca href=\u0022https:\/\/cocosys.ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ECenter for the Co-Design of Cognitive Systems\u003C\/strong\u003E\u003C\/a\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EArijit Raychowdhury has been the Steve W. Chaddick School Chair of ECE since 2021. He is a leading innovator in semiconductor technologies, holding more than 27 U.S. and international patents and authoring over 350 publications.\u003C\/p\u003E\u003Cp\u003EHis work spans low-power circuits, specialized accelerators, and system-on-chip design, with breakthroughs widely adopted in industry.\u003C\/p\u003E\u003Cp\u003E\u201cThis recognition reflects the collective effort of students, colleagues, and partners who share a vision for advancing microelectronics,\u201d said Raychowdhury. \u201cI am honored that NAI champions the same mission to lead through research, education, and innovation.\u0022\u003C\/p\u003E\u003Cp\u003EAt Texas Instruments, he developed the world\u2019s first adaptive echo-cancellation network for integrated Digital Subscriber Lines (DSL)\u2014a patented technology that enabled high-speed internet over traditional phone lines that received the EDN Innovation of the Year award. At Intel, he developed and incorporated foundational memory and logic technologies that shaped commercial products across global markets for more than a decade.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EHis research on fine-grain power management of systems-on-chip at Georgia Tech has been licensed and widely adopted by the semiconductor industry.\u003C\/p\u003E\u003Cp\u003EHe directs Georgia Tech\u2019s \u003Ca href=\u0022https:\/\/Georgia Tech\u2019s Center for the Co-Design of Cognitive Systems \u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003ECenter for the Co-Design of Cognitive Systems\u003C\/strong\u003E\u003C\/a\u003E and leads initiatives to advance microelectronics design with applications to AI. Over the years, he has served as a founding advisor and board member to multiple startups in the areas of edge-computing and low power design.\u003C\/p\u003E\u003Cdiv\u003E\u003Cp\u003ERaychowdhury\u2019s research bridges invention and real-world impact, earning him numerous honors, including IEEE\u0026nbsp;Fellow, \u003Ca href=\u0022https:\/\/ece.gatech.edu\/news\/2023\/12\/raychowdhury-chosen-src-technical-excellence-award\u0022\u003E\u003Cstrong\u003ESemiconductor Research Corporation Technical Excellence Award\u003C\/strong\u003E\u003C\/a\u003E, and multiple industry awards. Through pioneering designs and mentorship, he continues to drive innovation in computing systems, influencing both academic research and industrial commercialization.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":[{"value":"Divan, Raychowdhury Named National Academy of Inventors Fellows"}],"field_summary":[{"value":"\u003Cp\u003E\u003Cstrong\u003EDivan, Raychowdhury Named National Academy of Inventors Fellows\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Divan, Raychowdhury Named National Academy of Inventors Fellows"}],"uid":"36172","created_gmt":"2025-12-11 14:36:38","changed_gmt":"2025-12-12 14:36:15","author":"dwatson71","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-12-11T00:00:00-05:00","iso_date":"2025-12-11T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"678826":{"id":"678826","type":"image","title":"Divan-and-Arijit_NAI-Fellows-2025.png","body":null,"created":"1765463811","gmt_created":"2025-12-11 14:36:51","changed":"1765463811","gmt_changed":"2025-12-11 14:36:51","alt":"Deepak and Arijit headshot","file":{"fid":"262914","name":"Divan-and-Arijit_NAI-Fellows-2025.png","image_path":"\/sites\/default\/files\/2025\/12\/11\/Divan-and-Arijit_NAI-Fellows-2025.png","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/12\/11\/Divan-and-Arijit_NAI-Fellows-2025.png","mime":"image\/png","size":3056772,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/12\/11\/Divan-and-Arijit_NAI-Fellows-2025.png?itok=WD-DCWjq"}}},"media_ids":["678826"],"groups":[{"id":"655285","name":"GT Commercialization"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"136","name":"Aerospace"},{"id":"144","name":"Energy"},{"id":"145","name":"Engineering"},{"id":"194609","name":"Industry"},{"id":"132","name":"Institute Leadership"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"192255","name":"go-commercializationnews"}],"core_research_areas":[{"id":"193658","name":"Commercialization"}],"news_room_topics":[{"id":"71881","name":"Science and Technology"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EDan Watson\u003C\/p\u003E","format":"limited_html"}],"email":["dwatson@ece.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"686657":{"#nid":"686657","#data":{"type":"news","title":"IMS Launches Series on Interdisciplinary Innovation with AI Computing Panel ","body":[{"value":"\u003Cp\u003EThe Institute for Matter and Systems (IMS) hosted the inaugural Boundaries and Breakthroughs\u003Cem\u003E\u0026nbsp;\u003C\/em\u003Epanel on Nov. 11, setting the stage for a new era of interdisciplinary dialogue at Georgia Tech. The event, held in the Marcus Nanotechnology building, brought together experts in electrical engineering, computer architecture, and computer systems design to tackle one of today\u2019s pressing challenges: artificial intelligence (AI) scalability and sustainable high-performance computing.\u003C\/p\u003E\u003Cp\u003EAs one of Georgia Tech\u2019s 11 interdisciplinary research institutes, IMS is designed to break down silos between traditional academic units. By operating core user facilities and fostering collaborative research, IMS creates a unique ecosystem where device-level innovation meets systems-level design. This event personified that mission by connecting researchers who typically work on different ends of the stack.\u003C\/p\u003E\u003Cp\u003E\u201cWe\u2019re looking for opportunities to bring people together to have discussions that are both informative and potentially create a little bit of friction in the best possible way around trending topics in science and engineering,\u201d said Mike Filler, IMS deputy director, during opening remarks.\u003C\/p\u003E\u003Cp\u003EThe panel was moderated by \u003Ca href=\u0022http:\/\/ece.gatech.edu\/directory\/divya-mahajan\u0022\u003EDivya Mahajan\u003C\/a\u003E, assistant professor in the School of Electrical and Computer Engineering, and featured \u003Ca href=\u0022https:\/\/moin.cc.gatech.edu\/\u0022\u003EMoinuddin Qureshi\u003C\/a\u003E, professor of computer science; \u003Ca href=\u0022https:\/\/www.scs.gatech.edu\/people\/anand-padmanabha-iyer\u0022\u003EAnand Iyer\u003C\/a\u003E, assistant professor of computer science; and \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/people\/asif-khan\u0022\u003EAsif Khan\u003C\/a\u003E, associate professor in electrical and computer engineering.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe discussion explored the dynamics between compute abundance and energy constraints. As AI models scale up, power consumption has become a societal issue, driving up energy demands and even influencing political conversations. The panelists agreed that the bottleneck isn\u2019t compute \u2014 a computer\u2019s ability to process and execute tasks \u2014 but data movement. Moving data uses 100 to 1,000 times more energy than computation, making memory systems the critical frontier.\u003C\/p\u003E\u003Cp\u003EThe conversation highlighted how breakthroughs in compute must occur at every layer \u2014 from individual devices to full computer systems. At the device level, Khan mentioned emerging memory technologies and \u201cbeyond CMOS\u201d approaches such as embedding compute within memory and exploring bio-inspired architectures.\u003C\/p\u003E\u003Cp\u003EFrom a computer architecture level, Qureshi advocated rethinking interfaces and creating designs optimized for the future of computing. AI needs regular patterns to work optimally, and current patterns are not set up for that.\u003C\/p\u003E\u003Cp\u003E\u201cIf you want efficiency, design systems that make sense for AI,\u201d Qureshi said. \u201cDevelop new interfaces, develop new modules, architectures, and organization that make for a specific pattern.\u201d\u003C\/p\u003E\u003Cp\u003EAt the systems level, Iyer stressed practical strategies like near-memory compute and energy-aware scheduling while acknowledging the need for co-design between hardware and software.\u003C\/p\u003E\u003Cp\u003E\u201cNow in terms of brains or bio-inspired computing, my conjecture is that there is currently no hardware that is capable of doing it,\u201d Khan said. He also noted that right now, there is no computer or algorithm that has the scale of computing comparable to human brain power.\u003C\/p\u003E\u003Cp\u003EThe panelists didn\u2019t shy away from provocative ideas \u2014 such as whether graphic processing units are the final solution for AI and whether matrix multiplication alone can lead to artificial general intelligence. While opinions varied, all agreed that organizations like IMS are key to bringing together diverse expertise to tackle these questions collaboratively.\u003C\/p\u003E\u003Cp\u003EThe Boundaries and Breakthroughs series continues in \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/events\/boundaries-breakthroughs-panel-series-bioelectronics-med-tech\u0022\u003EJanuary with a panel on bioelectronics and medical technologies\u003C\/a\u003E, reinforcing IMS\u2019s commitment to fostering dialogue that spans the full spectrum of innovation.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe Boundaries and Breakthroughs panel explored how interdisciplinary collaboration can drive solutions for the future of artificial intelligence.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"The Boundaries and Breakthroughs panel explored how interdisciplinary collaboration can drive solutions for the future of artificial intelligence. "}],"uid":"35272","created_gmt":"2025-12-01 17:02:37","changed_gmt":"2025-12-01 17:03:39","author":"aneumeister3","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-12-01T00:00:00-05:00","iso_date":"2025-12-01T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"678737":{"id":"678737","type":"image","title":"BB_web_story.png","body":null,"created":"1764608566","gmt_created":"2025-12-01 17:02:46","changed":"1764608566","gmt_changed":"2025-12-01 17:02:46","alt":"Panelists speaking at the Boundaries and Breakthroughs panel series","file":{"fid":"262809","name":"BB_web_story.png","image_path":"\/sites\/default\/files\/2025\/12\/01\/BB_web_story.png","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/12\/01\/BB_web_story.png","mime":"image\/png","size":4029223,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/12\/01\/BB_web_story.png?itok=zYZRftI4"}}},"media_ids":["678737"],"groups":[{"id":"660369","name":"Matter and Systems"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"194606","name":"Artificial Intelligence"},{"id":"153","name":"Computer Science\/Information Technology and Security"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"193655","name":"Artificial Intelligence at Georgia Tech"},{"id":"193652","name":"Matter and Systems"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:amelia.neumeister@research.gatech.edu\u0022\u003EAmelia Neumeister\u003C\/a\u003E | Research Communications Program Manager\u003C\/p\u003E\u003Cp\u003EThe Institute for Matter and Systems\u003C\/p\u003E","format":"limited_html"}],"email":["amelia.neumeister@research.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"686192":{"#nid":"686192","#data":{"type":"news","title":"Built in I2P: The Student Inventions You\u2019ll Want to See to Believe","body":[{"value":"\u003Cp\u003ECricket powder-based protein brownies. A visualization system for fencing blades. A personalized AI application for analyzing blood work. All I2P Showcase prototypes. See what Georgia Tech students have been developing this semester at the \u003Ca href=\u0022https:\/\/www.eventbrite.com\/e\/i2p-showcase-fall-2025-tickets-1748117429289?aff=article\u0022\u003EFall 2025 Idea to Prototype (I2P) Showcase\u003C\/a\u003E on Tuesday, Dec. 2, at 5 p.m. in the Marcus Nanotechnology Building. This year, attendees will have even more\u0026nbsp;original inventions to view, with over 60 teams\u0026nbsp;displaying prototypes.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe event marks the culmination of the semester-long I2P course, where undergraduate students develop functional prototypes aimed at solving real-world problems. Prototypes this semester include a smart military drone, a gentler device for cervical cancer screening, a rotating espresso station, tools to keep AI safe, compact data centers, systems that simulate cyberattacks to help companies strengthen their defenses, and many more.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe showcase is free and open to students, faculty, staff, and members of the local community.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EWinning teams will receive prizes and a \u201cgolden ticket\u201d into CREATE-X\u2019s Startup Launch, a summer accelerator that provides optional seed funding, accounting and legal service credits, mentorship, and more to help students turn their prototypes into viable startups.\u003C\/p\u003E\u003Cp\u003EThis is a free event, and refreshments will be provided.\u0026nbsp;\u003Ca href=\u0022https:\/\/www.eventbrite.com\/e\/i2p-showcase-fall-2025-tickets-1748117429289?aff=article\u0022\u003ERegister for the Fall 2025 I2P Showcase\u003C\/a\u003E today!\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EMore than 60 undergraduate teams will present functional prototypes at the Fall 2025 Idea to Prototype (I2P) Showcase at Georgia Tech, Tuesday, Dec. 2 at 5 p.m. in the Marcus Nanotechnology Building. See innovative student creations developed over the semester and designed to solve real-world problems. Winning teams earn prizes and a \u201cgolden ticket\u201d into CREATE-X\u2019s Startup Launch accelerator, which offers funding, in-kind services, mentorship, and more. This is a free event for the campus and local community.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Georgia Tech\u2019s Fall 2025 I2P Showcase will feature over 60 student prototypes tackling real-world challenges."}],"uid":"36436","created_gmt":"2025-11-04 20:30:14","changed_gmt":"2025-11-04 20:45:46","author":"bdurham31","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-11-04T00:00:00-05:00","iso_date":"2025-11-04T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"678542":{"id":"678542","type":"image","title":"Founders of Allez Go Adam Kulikowski and Jason Mo","body":"\u003Cp\u003EFounders of Allez Go: Adam Kulikowski and Jason Mo\u003C\/p\u003E","created":"1762288717","gmt_created":"2025-11-04 20:38:37","changed":"1762288817","gmt_changed":"2025-11-04 20:40:17","alt":"Founders of Allez Go: Adam Kulikowski and Jason Mo","file":{"fid":"262593","name":"54186413447_045f318b99_o.jpg","image_path":"\/sites\/default\/files\/2025\/11\/04\/54186413447_045f318b99_o.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/11\/04\/54186413447_045f318b99_o.jpg","mime":"image\/jpeg","size":13446225,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/11\/04\/54186413447_045f318b99_o.jpg?itok=AFgCbVoS"}}},"media_ids":["678542"],"related_links":[{"url":"https:\/\/www.eventbrite.com\/e\/i2p-showcase-fall-2025-tickets-1748117429289?aff=article","title":"Register for the 2025 Fall I2P Showcase"}],"groups":[{"id":"583966","name":"CREATE-X"},{"id":"655285","name":"GT Commercialization"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"194606","name":"Artificial Intelligence"},{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"139","name":"Business"},{"id":"153","name":"Computer Science\/Information Technology and Security"},{"id":"42921","name":"Exhibitions"},{"id":"146","name":"Life Sciences and Biology"},{"id":"194685","name":"Manufacturing"},{"id":"147","name":"Military Technology"},{"id":"148","name":"Music and Music Technology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"133","name":"Special Events and Guest Speakers"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"192255","name":"go-commercializationnews"}],"core_research_areas":[{"id":"193658","name":"Commercialization"}],"news_room_topics":[{"id":"71871","name":"Campus and Community"},{"id":"71881","name":"Science and Technology"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EBreanna Durham\u003C\/p\u003E\u003Cp\u003EMarketing Strategist\u003C\/p\u003E","format":"limited_html"}],"email":["breanna.durham@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"683715":{"#nid":"683715","#data":{"type":"news","title":"Institute for Matter and Systems Expands Cleanroom Facilities ","body":[{"value":"\u003Cdiv\u003E\u003Cp\u003EThe \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EInstitute for Matter and Systems (IMS)\u003C\/a\u003E has completed a major expansion of its \u003Ca href=\u0022http:\/\/cleanroom.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003Ecleanroom facilities\u003C\/a\u003E, which now totals more than 23,000 square feet \u2013 solidifying its position as the largest academic cleanroom in the Southeast.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThe expansion includes a newly constructed 2,000-square-foot ISO 6 cleanroom, designed to house an advanced packaging and 3D heterogeneous integration (3DHI) facility.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cAs demand for cleanroom facilities continues to rise across academia and industry, this expansion strategically positions Georgia Tech to support national initiatives and advance global leadership in semiconductor packaging technologies,\u201d said \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/people\/gary-spinner\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EGary Spinner\u003C\/a\u003E, associate director of cleanroom and fabrication facilities at IMS.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThis state-of-the-art space will be equipped with next-generation processing and inspection capabilities that represent the next generation of semiconductor manufacturing technology.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cThe new facility, in conjunction with our existing Marcus facilities, will provide the campus community and our industry and government partners with the tools and capabilities to pursue revolutionary technologies in advanced packaging and 3D heterogeneous integration,\u201d said \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/people\/muhannad-s-bakir\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EMuhannad Bakir\u003C\/a\u003E, Dan Fielder Professor in the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003ESchool of Electrical and Computer Engineering\u003C\/a\u003E and director of the \u003Ca href=\u0022https:\/\/prc.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003E3D Systems Packaging Research Center\u003C\/a\u003E (PRC). \u201cThese innovations will include developing radical\u202fadvanced packaging and 3D stack architectures that seamlessly integrate electronics, photonics, power delivery, and thermal technologies.\u201d\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThe PRC will use the new facility for advanced packaging research supported by multiple national programs and industry partnerships. \u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp lang=\u0022EN-US\u0022\u003EThis robust infrastructure will support emerging applications in artificial intelligence, high-performance computing, and advanced mm-wave and photonic communications systems. By enabling the dense integration of multiple specialized chips within substrates and chip stacks, the pursued advanced packaging research will deliver more scalable, powerful and energy efficient systems at lower cost and shorter design cycles. \u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ENew 2,000-square-foot ISO 6 cleanroom advances semiconductor packaging innovation\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"New 2,000-square-foot ISO 6 cleanroom advances semiconductor packaging innovation "}],"uid":"35272","created_gmt":"2025-08-11 19:10:10","changed_gmt":"2025-08-13 16:05:03","author":"aneumeister3","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-08-11T00:00:00-04:00","iso_date":"2025-08-11T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"677648":{"id":"677648","type":"image","title":"Cleanroom_expansion.jpeg","body":null,"created":"1754941060","gmt_created":"2025-08-11 19:37:40","changed":"1754941060","gmt_changed":"2025-08-11 19:37:40","alt":"Inside the new Marcus Nanotechnology Building cleanroom space","file":{"fid":"261566","name":"Cleanroom_expansion.jpeg","image_path":"\/sites\/default\/files\/2025\/08\/11\/Cleanroom_expansion.jpeg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/08\/11\/Cleanroom_expansion.jpeg","mime":"image\/jpeg","size":202567,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/08\/11\/Cleanroom_expansion.jpeg?itok=FxS5sK9T"}},"677649":{"id":"677649","type":"image","title":"Media--7-.jpeg","body":null,"created":"1754941096","gmt_created":"2025-08-11 19:38:16","changed":"1754941096","gmt_changed":"2025-08-11 19:38:16","alt":"Inside the new Marcus Nanotechnology Building cleanroom space","file":{"fid":"261567","name":"Media--7-.jpeg","image_path":"\/sites\/default\/files\/2025\/08\/11\/Media--7-.jpeg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/08\/11\/Media--7-.jpeg","mime":"image\/jpeg","size":562830,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/08\/11\/Media--7-.jpeg?itok=T9cPFpIu"}},"677650":{"id":"677650","type":"image","title":"Media--8-.jpeg","body":null,"created":"1754941096","gmt_created":"2025-08-11 19:38:16","changed":"1754941096","gmt_changed":"2025-08-11 19:38:16","alt":"Inside the new cleanroom expansion","file":{"fid":"261568","name":"Media--8-.jpeg","image_path":"\/sites\/default\/files\/2025\/08\/11\/Media--8-.jpeg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/08\/11\/Media--8-.jpeg","mime":"image\/jpeg","size":645617,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/08\/11\/Media--8-.jpeg?itok=obIZFsPi"}}},"media_ids":["677648","677649","677650"],"groups":[{"id":"660369","name":"Matter and Systems"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"194685","name":"Manufacturing"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"193652","name":"Matter and Systems"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:amelia.neumeister@research.gatech.edu\u0022\u003EAmelia Neumeister\u003C\/a\u003E | Research Communications Program Manager\u003C\/p\u003E\u003Cp\u003EThe Institute for Matter and Systems\u003C\/p\u003E","format":"limited_html"}],"email":["amelia.neumeister@research.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"683062":{"#nid":"683062","#data":{"type":"news","title":"Lighting the Way to Faster Data Transfer","body":[{"value":"\u003Cp\u003EThe future of computing is lit, literally.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EAs microchips grow more complex and data demands intensify, traditional electrical connections are hitting their limits. Speed is king in today\u2019s digital systems, but a major bottleneck remains in how quickly information can move between components like processors and memory.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThis lag is one of the most pressing challenges in advanced hardware design. While processors continue to accelerate, the links that connect them can\u0027t keep pace.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EGeorgia Tech researcher \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/ali-adibi\u0022\u003E\u003Cstrong\u003EAli Adibi\u003C\/strong\u003E\u003C\/a\u003E is addressing this problem with $5.3 million in funding over three years from the Defense Advanced Research Projects Agency (DARPA). His project is part of DARPA\u2019s \u003Ca href=\u0022https:\/\/www.darpa.mil\/research\/programs\/happi-heterogeneous\u0022 rel=\u0022noreferrer\u0022\u003E\u003Cstrong\u003EHeterogeneous Adaptively Produced Photonic Interfaces\u003C\/strong\u003E\u003C\/a\u003E (HAPPI) program, which aims to dramatically boost the speed and density of data transmission within microsystems by using light instead of electricity.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cOptical solutions are highly advantageous for providing the required data rates and power consumptions, and our project is formed to address the most important challenges for achieving the system-level performance,\u201d said Adibi, a professor and Joseph M. Pettit Chair in the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003ESchool of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe project brings together a multidisciplinary team, including collaborators from the Massachusetts Institute of Technology, University of Florida, NY CREATES, and NHanced Semiconductors, Inc.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EGoing Vertical\u003C\/strong\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EUnlike traditional optical communication, which connects systems across distances, this project focuses on enabling ultra-fast, low-loss communication \u003Cem\u003Ewithin\u003C\/em\u003Eelectronic systems.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe key innovation is vertically connecting electronic chips in a compact stack. This design helps overcome the limitations of planar optical routing geometries (layouts that guide light horizontally across a chip) which are often not compatible with the dense, 3D chip architectures needed for next-generation computing.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EAdibi\u2019s team is developing a novel 3D optical routing system that can transmit data with minimal loss, high bandwidth, and compact components. The system is designed to scale to large arrays of interconnected chips with minimal interference between data channels.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ESmarter Design with Machine Learning\u003C\/strong\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EAt the heart of the project is the use of machine learning (ML) to help design and optimize the light-based communication system.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EML is used to shape and fine-tune the tiny structures that guide light through and between chips. This includes finding the best sizes, shapes, and layouts for components like couplers and waveguides, so they can be made smaller, work more efficiently, and fit into dense chip layouts.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cDesigning a complete, scalable 3D optical routing structure involves innumerable variables,\u201d Adibi said. \u201cMachine learning helps us navigate that complexity and find solutions that would be nearly impossible to identify manually.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETiny \u0022Mirrors\u0022\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EAnother key innovation involves specialized optical structures, or what Adibi refers to as \u201cartificial mirrors\u201d.\u003C\/p\u003E\u003Cp\u003EThe tiny, precisely shaped structures, called metagratings, are embedded in the chip material to redirect light vertically between layers with minimal loss. These components are designed to guide light efficiently in tight spaces, helping connect stacked chips without losing signal strength.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cImagine light traveling through a chip and suddenly being redirected straight up. That\u2019s the kind of precise control we\u2019re achieving,\u201d Adibi explained.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThese innovations, along with advanced techniques for building vertical light paths through thick silicon layers and new packaging solutions that keep components precisely aligned, have shown promise on their own. But combining them is what enables dense, high-speed, low-loss communication between vertically stacked chips, something that no system has achieved before, according to Adibi.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cAs with any complex system, success depends on how well everything is structured and optimized,\u201d he said. \u201cOnce everything is in alignment, data can move faster, more efficiently, and with less energy consumption for communicating each bit of data.\u201d\u003C\/p\u003E\u003Cp\u003E\u003Cbr\u003E\u003Cem\u003E\u003Cstrong\u003EAbout the Research\u003C\/strong\u003E\u003C\/em\u003E\u003Cbr\u003E\u003Cem\u003EThis research is supported by the Defense Advanced Research Projects Agency (DARPA) \u003C\/em\u003E\u003Ca href=\u0022https:\/\/www.darpa.mil\/research\/programs\/happi-heterogeneous\u0022 rel=\u0022noreferrer\u0022\u003E\u003Cem\u003E\u003Cstrong\u003EHeterogeneous Adaptively Produced Photonic Interfaces (HAPPI) program\u003C\/strong\u003E\u003C\/em\u003E\u003C\/a\u003E\u003Cem\u003E. Notice ID DARPA-SN-24-105.\u003C\/em\u003E\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EDARPA is backing Professor Ali Adibi\u2019s work to use light, not electricity, to move data faster and more efficiently in next-generation electronics.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"DARPA is backing Professor Ali Adibi\u2019s work to use light, not electricity, to move data faster and more efficiently in next-generation electronics. "}],"uid":"36172","created_gmt":"2025-07-09 18:43:36","changed_gmt":"2025-07-09 18:49:29","author":"dwatson71","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-07-09T00:00:00-04:00","iso_date":"2025-07-09T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"677375":{"id":"677375","type":"image","title":"25-2304-Darpa-Happi-Ali-Adibi-007.JPG","body":"\u003Cp\u003ESilicon-on-insulator (SOI) wafer used in a multi-chip module featuring 3D optical interconnects. \u003Cem\u003E(Photo: Allison Carter)\u003C\/em\u003E\u003C\/p\u003E","created":"1752086638","gmt_created":"2025-07-09 18:43:58","changed":"1752086638","gmt_changed":"2025-07-09 18:43:58","alt":"Photo of Silicon-on-insulator (SOI) wafer","file":{"fid":"261269","name":"25-2304-Darpa-Happi-Ali-Adibi-007.JPG","image_path":"\/sites\/default\/files\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-007.JPG","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-007.JPG","mime":"image\/jpeg","size":1306660,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-007.JPG?itok=b2dPJ-8H"}},"677376":{"id":"677376","type":"image","title":"MulitChip.jpg","body":"\u003Cp\u003EA schematic illustration of a multi-chip structure with 3D optical routing. The key parts of Adibi\u0027s proposed system are: 1) multi-layer planar waveguides, 2) free-form couplers, and 3) a dense vertical waveguide array.\u003C\/p\u003E","created":"1752086638","gmt_created":"2025-07-09 18:43:58","changed":"1752086638","gmt_changed":"2025-07-09 18:43:58","alt":"A schematic illustration of a multi-chip structure with 3D optical routing.","file":{"fid":"261270","name":"MulitChip.jpg","image_path":"\/sites\/default\/files\/2025\/07\/09\/MulitChip.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/07\/09\/MulitChip.jpg","mime":"image\/jpeg","size":7987738,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/07\/09\/MulitChip.jpg?itok=KD-djsVC"}},"677374":{"id":"677374","type":"image","title":"25-2304-Darpa-Happi-Ali-Adibi-006.JPG","body":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EBy combining advanced optical techniques, Professor Ali Adibi\u2019s 3D optical routing systems looks to enable vertical chip integration in a way not previously achieved. \u003Cem\u003E(Photo: Allison Carter)\u003C\/em\u003E\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","created":"1752086638","gmt_created":"2025-07-09 18:43:58","changed":"1752086638","gmt_changed":"2025-07-09 18:43:58","alt":"Professor Ali Adibi in front of testing equipment for his 3D optical routing system.","file":{"fid":"261268","name":"25-2304-Darpa-Happi-Ali-Adibi-006.JPG","image_path":"\/sites\/default\/files\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-006.JPG","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-006.JPG","mime":"image\/jpeg","size":1563309,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/07\/09\/25-2304-Darpa-Happi-Ali-Adibi-006.JPG?itok=NoOrAjDb"}}},"media_ids":["677375","677376","677374"],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"194610","name":"National Interests\/National Security"},{"id":"135","name":"Research"}],"keywords":[{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"39451","name":"Electronics and Nanotechnology"},{"id":"193652","name":"Matter and Systems"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EDan Watson\u003C\/p\u003E","format":"limited_html"}],"email":["dwatson@ece.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"681961":{"#nid":"681961","#data":{"type":"news","title":"Thesis on Human-Centered AI Earns Honors from International Computing Organization","body":[{"value":"\u003Cp\u003EA Georgia Tech alum\u2019s dissertation introduced ways to make artificial intelligence (AI) more accessible, interpretable, and accountable. Although it\u2019s been a year since his doctoral defense,\u0026nbsp;\u003Ca href=\u0022https:\/\/zijie.wang\/\u0022\u003E\u003Cstrong\u003EZijie (Jay) Wang\u003C\/strong\u003E\u003C\/a\u003E\u2019s (Ph.D. ML-CSE 2024) work continues to resonate with researchers.\u003C\/p\u003E\u003Cp\u003EWang is a recipient of the\u0026nbsp;\u003Ca href=\u0022https:\/\/medium.com\/sigchi\/announcing-the-2025-acm-sigchi-awards-17c1feaf865f\u0022\u003E\u003Cstrong\u003E2025 Outstanding Dissertation Award from the Association for Computing Machinery Special Interest Group on Computer-Human Interaction (ACM SIGCHI)\u003C\/strong\u003E\u003C\/a\u003E. The award recognizes Wang for his lifelong work on democratizing human-centered AI.\u003C\/p\u003E\u003Cp\u003E\u201cThroughout my Ph.D. and industry internships, I observed a gap in existing research: there is a strong need for practical tools for applying human-centered approaches when designing AI systems,\u201d said Wang, now a safety researcher at OpenAI.\u003C\/p\u003E\u003Cp\u003E\u201cMy work not only helps people understand AI and guide its behavior but also provides user-friendly tools that fit into existing workflows.\u201d\u003C\/p\u003E\u003Cp\u003E[Related: \u003Ca href=\u0022https:\/\/sites.gatech.edu\/research\/chi-2025\/\u0022\u003EGeorgia Tech College of Computing Swarms to Yokohama, Japan, for CHI 2025\u003C\/a\u003E]\u003C\/p\u003E\u003Cp\u003EWang\u2019s dissertation presented techniques in visual explanation and interactive guidance to align AI models with user knowledge and values. The work culminated from years of research, fellowship support, and internships.\u003C\/p\u003E\u003Cp\u003EWang\u2019s most influential projects formed the core of his dissertation. These included:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Ca href=\u0022https:\/\/poloclub.github.io\/cnn-explainer\/\u0022\u003E\u003Cstrong\u003ECNN Explainer\u003C\/strong\u003E\u003C\/a\u003E: an open-source tool developed for deep-learning beginners. Since its release in July 2020, more than 436,000 global visitors have used the tool.\u003C\/li\u003E\u003Cli\u003E\u003Ca href=\u0022https:\/\/poloclub.github.io\/diffusiondb\/\u0022\u003E\u003Cstrong\u003EDiffusionDB\u003C\/strong\u003E\u003C\/a\u003E: a first-of-its-kind large-scale dataset that lays a foundation to help people better understand generative AI. This work could lead to new research in detecting deepfakes and designing human-AI interaction tools to help people more easily use these models.\u003C\/li\u003E\u003Cli\u003E\u003Ca href=\u0022https:\/\/interpret.ml\/gam-changer\/\u0022\u003E\u003Cstrong\u003EGAM Changer\u003C\/strong\u003E\u003C\/a\u003E: an interface that empowers users in healthcare, finance, or other domains to edit ML models to include knowledge and values specific to their domain, which improves reliability.\u003C\/li\u003E\u003Cli\u003E\u003Ca href=\u0022https:\/\/www.jennwv.com\/papers\/gamcoach.pdf\u0022\u003E\u003Cstrong\u003EGAM Coach\u003C\/strong\u003E\u003C\/a\u003E: an interactive ML tool that could help people who have been rejected for a loan by automatically letting an applicant know what is needed for them to receive loan approval. \u003C\/li\u003E\u003Cli\u003E\u003Ca href=\u0022https:\/\/www.cc.gatech.edu\/news\/new-tool-teaches-responsible-ai-practices-when-using-large-language-models\u0022\u003E\u003Cstrong\u003EFarsight\u003C\/strong\u003E\u003C\/a\u003E: a tool that alerts developers when they write prompts in large language models that could be harmful and misused. \u0026nbsp;\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u201cI feel extremely honored and lucky to receive this award, and I am deeply grateful to many who have supported me along the way, including Polo, mentors, collaborators, and friends,\u201d said Wang, who was advised by School of Computational Science and Engineering (CSE) Professor\u0026nbsp;\u003Ca href=\u0022https:\/\/poloclub.github.io\/polochau\/\u0022\u003E\u003Cstrong\u003EPolo Chau\u003C\/strong\u003E\u003C\/a\u003E.\u003C\/p\u003E\u003Cp\u003E\u201cThis recognition also inspired me to continue striving to design and develop easy-to-use tools that help everyone to easily interact with AI systems.\u201d\u003C\/p\u003E\u003Cp\u003ELike Wang, Chau advised Georgia Tech alumnus\u0026nbsp;\u003Ca href=\u0022https:\/\/fredhohman.com\/\u0022\u003EFred Hohman\u003C\/a\u003E (Ph.D. CSE 2020).\u0026nbsp;\u003Ca href=\u0022https:\/\/www.cc.gatech.edu\/news\/alumnus-building-legacy-through-dissertation-and-mentorship\u0022\u003EHohman won the ACM SIGCHI Outstanding Dissertation Award in 2022\u003C\/a\u003E.\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/poloclub.github.io\/\u0022\u003EChau\u2019s group\u003C\/a\u003E synthesizes machine learning (ML) and visualization techniques into scalable, interactive, and trustworthy tools. These tools increase understanding and interaction with large-scale data and ML models.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EChau is the associate director of corporate relations for the Machine Learning Center at Georgia Tech. Wang called the School of CSE his home unit while a student in the ML program under Chau.\u003C\/p\u003E\u003Cp\u003EWang is one of five recipients of this year\u2019s award to be presented at the 2025 Conference on Human Factors in Computing Systems (\u003Ca href=\u0022https:\/\/chi2025.acm.org\/\u0022\u003ECHI 2025\u003C\/a\u003E). The conference occurs April 25-May 1 in Yokohama, Japan.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ESIGCHI is the world\u2019s largest association of human-computer interaction professionals and practitioners. The group sponsors or co-sponsors 26 conferences, including CHI.\u003C\/p\u003E\u003Cp\u003EWang\u2019s outstanding dissertation award is the latest recognition of a career decorated with achievement.\u003C\/p\u003E\u003Cp\u003EMonths after graduating from Georgia Tech,\u0026nbsp;\u003Ca href=\u0022https:\/\/www.cc.gatech.edu\/news\/research-ai-safety-lands-recent-graduate-forbes-30-under-30\u0022\u003EForbes named Wang to its 30 Under 30 in Science for 2025\u003C\/a\u003E for his dissertation. Wang was one of 15 Yellow Jackets included in nine different 30 Under 30 lists and the only Georgia Tech-affiliated individual on the 30 Under 30 in Science list.\u003C\/p\u003E\u003Cp\u003EWhile a Georgia Tech student, Wang earned recognition from big names in business and technology. He received the\u0026nbsp;\u003Ca href=\u0022https:\/\/www.cc.gatech.edu\/news\/student-named-apple-scholar-connecting-people-machine-learning\u0022\u003EApple Scholars in AI\/ML Ph.D. Fellowship in 2023\u003C\/a\u003E and was in the\u0026nbsp;\u003Ca href=\u0022https:\/\/www.cc.gatech.edu\/news\/georgia-tech-machine-learning-students-earn-jp-morgan-ai-phd-fellowships\u0022\u003E2022 cohort of the J.P. Morgan AI Ph.D. Fellowships Program\u003C\/a\u003E.\u003C\/p\u003E\u003Cp\u003EAlong with the CHI award, Wang\u2019s dissertation earned him awards this year at banquets across campus. The\u0026nbsp;\u003Ca href=\u0022https:\/\/bpb-us-e1.wpmucdn.com\/sites.gatech.edu\/dist\/0\/283\/files\/2025\/03\/2025-Sigma-Xi-Research-Award-Winners.pdf\u0022\u003EGeorgia Tech chapter of Sigma Xi presented Wang with the Best Ph.D. Thesis Award\u003C\/a\u003E. He also received the College of Computing\u2019s Outstanding Dissertation Award.\u003C\/p\u003E\u003Cp\u003E\u201cGeorgia Tech attracts many great minds, and I\u2019m glad that some, like Jay, chose to join our group,\u201d Chau said. \u201cIt has been a joy to work alongside them and witness the many wonderful things they have accomplished, and with many more to come in their careers.\u201d\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EA Georgia Tech alum\u2019s dissertation introduced ways to make artificial intelligence (AI) more accessible, interpretable, and accountable. Although it\u2019s been a year since his doctoral defense,\u0026nbsp;\u003Ca href=\u0022https:\/\/zijie.wang\/\u0022\u003E\u003Cstrong\u003EZijie (Jay) Wang\u003C\/strong\u003E\u003C\/a\u003E\u2019s (Ph.D. ML-CSE 2024) work continues to resonate with researchers.\u003C\/p\u003E\u003Cp\u003EWang is a recipient of the\u0026nbsp;\u003Ca href=\u0022https:\/\/medium.com\/sigchi\/announcing-the-2025-acm-sigchi-awards-17c1feaf865f\u0022\u003E\u003Cstrong\u003E2025 Outstanding Dissertation Award from the Association for Computing Machinery Special Interest Group on Computer-Human Interaction (ACM SIGCHI)\u003C\/strong\u003E\u003C\/a\u003E. The award recognizes Wang for his lifelong work on democratizing human-centered AI.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":" Zijie (Jay) Wang (Ph.D. ML-CSE 2024) is a recipient of the 2025 Outstanding Dissertation Award from the Association for Computing Machinery Special Interest Group on Computer-Human Interaction (ACM SIGCHI)."}],"uid":"36319","created_gmt":"2025-04-22 14:24:46","changed_gmt":"2025-04-22 14:29:07","author":"Bryant Wine","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-04-17T00:00:00-04:00","iso_date":"2025-04-17T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"676903":{"id":"676903","type":"image","title":"Jay-Wang-SIGCHI-Dissertation-Award.jpg","body":null,"created":"1745331896","gmt_created":"2025-04-22 14:24:56","changed":"1745331896","gmt_changed":"2025-04-22 14:24:56","alt":"Zijie (Jay) Wang CHI 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Achievements"},{"id":"8862","name":"Student Research"}],"keywords":[{"id":"654","name":"College of Computing"},{"id":"166983","name":"School of Computational Science and Engineering"},{"id":"187812","name":"artificial intelligence (AI)"},{"id":"181991","name":"Georgia Tech News Center"},{"id":"10199","name":"Daily Digest"},{"id":"9153","name":"Research Horizons"},{"id":"187915","name":"go-researchnews"},{"id":"192863","name":"go-ai"}],"core_research_areas":[{"id":"193655","name":"Artificial Intelligence at Georgia Tech"},{"id":"39431","name":"Data Engineering and Science"},{"id":"39501","name":"People and Technology"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EBryant Wine, Communications Officer\u003Cbr\u003E\u003Ca href=\u0022mailto:bryant.wine@cc.gatech.edu\u0022\u003Ebryant.wine@cc.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"681109":{"#nid":"681109","#data":{"type":"news","title":"Georgia Tech to Grenoble: Amira Bencherif Awarded MSCA Fellowship","body":[{"value":"\u003Cp dir=\u0022ltr\u0022\u003EFrom developing more sustainable computer chips to advancing quantum and high-performance computing,\u0026nbsp;the new frontier of nanoelectronics could lie with graphene, a material related to ordinary pencil graphite that\u2019s made from a single sheet of carbon atoms.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EOne physicist helping lead this charge is \u003Ca href=\u0022https:\/\/postdocs.gatech.edu\/news\/one-postdoctoral-scholars-journey-france-cutting-edge-electronics-georgia-tech\u0022\u003E\u003Cstrong\u003EAmira Bencherif\u003C\/strong\u003E\u003C\/a\u003E, a postdoctoral researcher in the \u003Ca href=\u0022https:\/\/www.graphene.gatech.edu\/\u0022\u003EEpigraphene Lab\u003C\/a\u003E at Georgia Tech, which aims to advance electronics past the limitations of silicon using graphene\u2019s extraordinary electrical properties.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EBencherif has just been awarded a prestigious European Marie Sk\u0142odowska-Curie Action (MSCA) global post-doctoral fellowship; This year, it is expected that \u003Ca href=\u0022https:\/\/marie-sklodowska-curie-actions.ec.europa.eu\/news\/msca-postdoctoral-fellowships-2024-receives-10360-proposals\u0022\u003Efewer than 20% of applicants will be selected from a record pool of over 10,000 submissions\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EThe highly selective fellowship will support two additional years of research at Georgia Tech with The Epigraphene Lab,\u0026nbsp;followed by\u0026nbsp;Bencherif working for\u0026nbsp;one year at the \u003Ca href=\u0022https:\/\/www.pheliqs.fr\/\u0022\u003ECEA-PHELIQS Lab\u003C\/a\u003E in Grenoble, France.\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003E\u201cThe\u0026nbsp;research in Grenoble is a critical component,\u201d Bencherif explains. \u201cOur Georgia Tech team brings the graphene expertise, and the\u0026nbsp;CEA-PHELIQS Lab brings expertise in extreme low-temperature research. Combining these two areas will let me\u0026nbsp;investigate graphene properties at extreme low temperatures, for the first time.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EThe group hopes the research will lead to breakthroughs in sustainable electronics and manufacturing. \u201cWe already know that epigraphene can be used as either as a conductor or as an ultra-high mobility semiconductor,\u201d Bencherif says. \u201cWe\u0027re still in the fundamental research phase with this new project, but combining both properties of this material on a single chip could result in very fast electronics, very small devices, and more sustainable computing.\u201d\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Ch3\u003E\u003Cstrong\u003EGrowing graphene\u0026nbsp;\u003C\/strong\u003E\u0026nbsp;\u003C\/h3\u003E\u003Cp dir=\u0022ltr\u0022\u003EThe fellowship builds on a longstanding partnership.\u003Cem\u003E\u0026nbsp;\u003C\/em\u003E\u201cWe\u0027ve collaborated with our French partners on previous papers, and we have a great line of communication and trust,\u201d shares \u003Ca href=\u0022https:\/\/physics.gatech.edu\/user\/claire-berger\u0022\u003E\u003Cstrong\u003EClaire Berger\u003C\/strong\u003E\u003C\/a\u003E, who works in the Epigraphene Lab directed by Regents\u0027 Professor \u003Ca href=\u0022https:\/\/physics.gatech.edu\/user\/walter-de-heer\u0022\u003E\u003Cstrong\u003EWalter de Heer\u003C\/strong\u003E\u003C\/a\u003E at Georgia Tech.\u0026nbsp;\u201cThis prestigious fellowship is a recognition not only of Amira\u2019s skills, talent and dedication as a researcher, but also of the quality of the epigraphene scientific program and the strength of the French-American collaboration.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EBerger, who serves as a professor of the practice at Georgia Tech, recently received \u003Ca href=\u0022https:\/\/cos.gatech.edu\/news\/claire-berger-receives-one-frances-highest-civilian-honors-science-scientific-diplomacy\u0022\u003Eone of France\u2019s highest civilian honors\u003C\/a\u003E in science and scientific diplomacy, the Chevalier dans L\u0027ordre des Palmes Acad\u00e9miques. She is also the Director of Research at the \u003Ca href=\u0022https:\/\/www.cnrs.fr\/en\/cnrs\u0022\u003EFrench National Center for Scientific Research (CNRS) International Research Lab\u003C\/a\u003E, which has a main presence at \u003Ca href=\u0022https:\/\/europe.gatech.edu\/en\/campuses\/metz\u0022\u003EGeorgia Tech-Europe\u003C\/a\u003E in Metz, France, as well as a mirror site at Georgia Tech\u2019s Atlanta campus.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003E\u201cTo advance this field, collaboration is crucial,\u201d Berger says. \u201cWe cannot do it alone \u2014 the MSCA support for Amira\u2019s work is both a testament to her hard work and the important partnership with our French counterparts.\u201d\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Ch3\u003E\u003Cstrong\u003EThe future of graphene\u003C\/strong\u003E\u0026nbsp;\u003C\/h3\u003E\u003Cp dir=\u0022ltr\u0022\u003EOne key aspect of the Epigraphene Lab\u2019s research involves \u003Ca href=\u0022https:\/\/news.gatech.edu\/news\/2022\/12\/21\/edge-graphene-based-electronics\u0022\u003Edeveloping a graphene semiconductor ten times more conductive than silicon\u003C\/a\u003E that has the potential to create a new kind of electronics.\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003E\u201cComplementing its semiconducting property, some form of epigraphene has special pathways which make electronic mobility extremely high,\u201d Bencherif explains. \u201cThis has benefits like less energy dissipation, which is important for addressing global warming and energy challenges. We use epigraphene \u2014 which is graphene grown on a silicon carbide substrate \u2014 to make electrical devices and study their electrical properties.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003E\u201cWe also suspect we can use another mode of communication with current, based on the wave quantum nature of the electron, leading to coherent electronics,\u201d which Berger shares is a long-term research project the group is pursuing.\u0026nbsp;\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003E\u201cThis type of work is very prospective and ambitious, which is why Amira was granted this prestigious fellowship,\u201d Berger adds. \u201cThis type of research is a lot of hard work. To drive this work forward, Amira has put in an astonishing number of hours and a lot of thoughtful effort. She\u0027s incredibly creative, and it\u0027s an honor to work with her.\u201d\u0026nbsp;\u0026nbsp;\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe international fellowship will support two years of research at Georgia Tech, and one year of research at the French CEA-PHELIQS Lab, where Bencherif will explore graphene\u2019s unique electrical properties.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"The international fellowship will support two years of research at Georgia Tech, and one year of research at the French CEA-PHELIQS Lab, where Bencherif will explore graphene\u2019s unique electrical properties. "}],"uid":"35599","created_gmt":"2025-03-11 19:58:05","changed_gmt":"2025-03-20 16:38:20","author":"sperrin6","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-03-19T00:00:00-04:00","iso_date":"2025-03-19T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"676522":{"id":"676522","type":"image","title":"Claire Berger holds a graphene device grown on a silicon carbide substrate chip. Credit: Jess Hunt-Ralston","body":"\u003Cp\u003EClaire Berger holds a graphene device grown on a silicon carbide substrate chip. Credit: Jess Hunt-Ralston\u003C\/p\u003E","created":"1741723539","gmt_created":"2025-03-11 20:05:39","changed":"1741723585","gmt_changed":"2025-03-11 20:06:25","alt":"Claire Berger holds a graphene device grown on a silicon carbide substrate chip. Credit: Jess Hunt-Ralston","file":{"fid":"251365","name":"Claire holds chip eedit.jpg","image_path":"\/sites\/default\/files\/images\/Claire%20holds%20chip%20eedit.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/Claire%20holds%20chip%20eedit.jpg","mime":"image\/jpeg","size":785389,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/Claire%20holds%20chip%20eedit.jpg?itok=TVWtbAn0"}}},"media_ids":["676522"],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"126011","name":"School of Physics"}],"categories":[{"id":"153","name":"Computer Science\/Information Technology and Security"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"150","name":"Physics and Physical Sciences"},{"id":"135","name":"Research"},{"id":"8862","name":"Student Research"}],"keywords":[{"id":"192249","name":"cos-community"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EWritten by Selena Langner\u003C\/p\u003E\u003Cp\u003EContact: \u003Ca href=\u0022mailto: jess.hunt@cos.gatech.edu\u0022\u003EJess Hunt-Ralston\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"679741":{"#nid":"679741","#data":{"type":"news","title":"Georgia Tech Joins $840M DoD Project to Develop and Manufacture Next-gen Semiconductor Microsystems","body":[{"value":"\u003Cp lang=\u0022EN-US\u0022\u003EGeorgia Institute of Technology is set to play a crucial role in a strategic effort funded by the Defense Advanced Research Project Agency (DARPA) to help bolster America\u2019s national security and global military leadership.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe project, led by the Texas Institute for Electronics (TIE) at The University of Texas at Austin, represents a total investment of $1.4 billion. The $840 million award from DARPA, \u003Ca href=\u0022https:\/\/news.utexas.edu\/2024\/07\/18\/uts-texas-institute-for-electronics-awarded-840m-to-build-a-dod-microelectronics-manufacturing-center-advance-u-s-semiconductor-industry\/\u0022\u003Eannounced by TIE in 2024\u003C\/a\u003E, aims to develop the next generation of high-performing semiconductor microsystems for the Department of Defense (DoD).\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cWe are honored to collaborate with TIE and its broader team on this far reaching and strategic program to enable best in class 3D heterogeneous integration (3DHI) processes and technologies in the United States,\u201d said \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/muhannad-s-bakir\u0022\u003EMuhannad S. Bakir\u003C\/a\u003E, the Dan Fielder Professor in the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003ESchool of Electrical and Computer Engineering\u003C\/a\u003E and director of the \u003Ca href=\u0022https:\/\/sites.gatech.edu\/ien-prc\/\u0022\u003E3D Systems Packaging Research Center\u003C\/a\u003E, who is heading the project for Georgia Tech.\u0026nbsp;\u003C\/p\u003E\u003Cp lang=\u0022EN-US\u0022\u003E3DHI is a semiconductor manufacturing process that incorporates different materials and components into microsystems with precision assembly. The use of 3DHI allows for the creation of high-performance, compact, and energy-efficient systems.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe investment is part of DARPA\u2019s Next Generation Microelectronics Manufacturing (NGMM) Program comprised of 32 defense electronics and leading commercial semiconductor companies and 18 nationally recognized academic institutions.\u003C\/p\u003E\u003Cp lang=\u0022EN-US\u0022\u003EUnder the agreement, TIE will establish a national open access R\u0026amp;D and prototyping fabrication facility. The facility will enable the DoD to create higher performance, lower power, lightweight, and compact defense systems. The advancements are expected to have wide-ranging applications, including radar, satellite imaging, and unmanned aerial vehicles.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EGeorgia Tech will provide a wide range of expertise in 3DHI including design, fabrication and assembly processes, and characterization to support the NGMM national open-access R\u0026amp;D and prototyping facility at TIE. \u0026nbsp;\u003C\/p\u003E\u003Cp lang=\u0022EN-US\u0022\u003ERegents\u0027 Professor and Morris M. Bryan, Jr. Professor \u003Ca href=\u0022https:\/\/me.gatech.edu\/faculty\/sitaraman\u0022\u003ESuresh K. Sitaraman\u003C\/a\u003E in the \u003Ca href=\u0022https:\/\/me.gatech.edu\/\u0022\u003EGeorge W. Woodruff School of Mechanical Engineering\u003C\/a\u003E will be a key contributor to Georgia Tech\u2019s efforts on the project.\u003C\/p\u003E\u003Cp\u003E\u201cWe are delighted to be partnering with UT\/TIE on the establishment of a 3D Heterogeneous Integration Microsystem prototyping \u0026nbsp;facility,\u201d said Sitaraman. \u201cIn addition to advancing fundamental science, this project is a great opportunity for Georgia Tech to demonstrate and integrate our ground-breaking and innovative 3DHI research approaches and technology solutions into TIE\u2019s prototyping facility, and understand the challenges involved when translating lab-scale research work to a large industry-strength fabrication facility.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EECE Professors \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/saibal-mukhopadhyay\u0022\u003ESaibal Mukhopadhyay\u003C\/a\u003E, \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/arijit-raychowdhury\u0022\u003EArijit Raychowdhury\u003C\/a\u003E, \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/visvesh-s-sathe\u0022\u003EVisvesh Sathe\u003C\/a\u003E, and \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/shimeng-yu\u0022\u003EShimeng Yu\u003C\/a\u003E\u0026nbsp;will be working alongside Bakir and Sitaraman.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EA significant portion of the research will be conducted at the \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/\u0022\u003EInstitute for Matter and Systems\u003C\/a\u003E (IMS), which operates Georgia Tech\u2019s state-of-the-art electronics and nanotechnology core facilities.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ERead the \u003Ca href=\u0022https:\/\/www.txie.org\/tifea\/\u0022\u003Epress release\u003C\/a\u003E from TIE and view the \u003Ca href=\u0022https:\/\/www.txie.org\/tifea\/#partners\u0022\u003Eproject\u2019s team and partners\u003C\/a\u003E.\u0026nbsp;\u0026nbsp;\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EResearchers will contribute extensive 3D heterogeneous integration expertise to the Texas Institute for Electronics-led initiative.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Researchers will contribute extensive 3D heterogeneous integration expertise to the Texas Institute for Electronics-led initiative. "}],"uid":"36172","created_gmt":"2025-01-21 14:58:25","changed_gmt":"2025-01-21 15:00:38","author":"dwatson71","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-01-21T00:00:00-05:00","iso_date":"2025-01-21T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"676070":{"id":"676070","type":"image","title":"Marcus Nanotechnology Building","body":null,"created":"1737471519","gmt_created":"2025-01-21 14:58:39","changed":"1737471519","gmt_changed":"2025-01-21 14:58:39","alt":"Photo of the Marcus Nanotechnology Building. A glass building with sunshine shining through in the top right corner. ","file":{"fid":"259780","name":"14C10042-P1-118.jpg","image_path":"\/sites\/default\/files\/2025\/01\/21\/14C10042-P1-118.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/01\/21\/14C10042-P1-118.jpg","mime":"image\/jpeg","size":5052208,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/01\/21\/14C10042-P1-118.jpg?itok=A13avPiW"}}},"media_ids":["676070"],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"690","name":"darpa"},{"id":"543","name":"National Security"},{"id":"167686","name":"Semiconductors"},{"id":"194237","name":"3D Heterogeneous Integration"},{"id":"99661","name":"Muhannad S. Bakir"},{"id":"194238","name":"Suresh K. Sitaraman"},{"id":"194239","name":"Texas Institute for Electronics"},{"id":"166900","name":"Saibal Mukhopadhyay"},{"id":"139771","name":"Arijit Raychowdhury"},{"id":"191068","name":"Visvesh Sathe"},{"id":"178857","name":"Shimeng Yu"},{"id":"166855","name":"School of Electrical and Computer Engineering"},{"id":"194240","name":"Three-Dimensional Systems Packaging Research Center"},{"id":"14545","name":"George W. Woodruff School of Mechanical Engineering"},{"id":"194241","name":"Institute for Matter and Systems"},{"id":"194242","name":"Next Generation Microelectronics Manufacturing"},{"id":"194243","name":"NGMM"}],"core_research_areas":[{"id":"39451","name":"Electronics and Nanotechnology"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EDan Watson\u003C\/p\u003E","format":"limited_html"}],"email":["dwatson@ece.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"679023":{"#nid":"679023","#data":{"type":"news","title":"Special Delivery Nanoparticle Sidesteps the \u2018Middlemen\u2019","body":[{"value":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EMiddlemen get a bad rap for adding cost and complications to an operation. So, eliminating the go-betweens can reduce expense and simplify a process, increasing efficiency and consumer happiness.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/faculty\/James-Dahlman\u0022\u003EJames Dahlman\u003C\/a\u003E and his research team have been thinking along those same lines for stem cell treatments. They\u2019ve created a technique that eliminates noisome middlemen and could lead to new, less-invasive treatments for blood disorders and genetic diseases. It sidesteps the discomfort and risks of current treatments, making life easier for patients.\u003C\/p\u003E\u003Cp\u003E\u201cThis would be an alternative to invasive hematopoietic stem cell therapies \u2014 we could just give you an IV drip,\u201d said Dahlman, McCamish Early Career Professor in the Wallace H. Coulter Department of Biomedical Engineering. \u201cIt simplifies the process and reduces the risks to patients. That\u2019s why this work is important.\u201d\u003C\/p\u003E\u003Cp\u003EDahlman and a team of investigators from Georgia Tech, Emory University, and the University of California, Davis, \u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41587-024-02470-2\u0022\u003Epublished their approach in the journal \u003Cem\u003ENature Biotechnology\u003C\/em\u003E\u003C\/a\u003E.\u003C\/p\u003E\u003Ch4\u003E\u003Cstrong\u003EMinding the Parents\u003C\/strong\u003E\u003C\/h4\u003E\u003Cp\u003EHematopoietic stem cells (HSCs) are like parent cells. Residing in the bone marrow, they produce all types of cells needed to sustain the blood and immune systems. Their versatility makes HSCs a valuable therapeutic tool in treating genetic blood diseases, such as sickle cell anemia, immune deficiencies, and some cancers.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EHSC therapies usually involve extracting cells from the patient\u2019s bone marrow and re-engineering them in a lab. Meanwhile, the patient endures chemotherapy to help prepare their body to receive the modified HSCs.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cThese therapies are effective but also hard on the patients,\u201d Dahlman said. \u201cPatients undergo chemotherapy to wipe out their immune systems so the body will accept the therapeutic cells without a fight. The procedure can be life-threatening. We\u2019re hoping to change that.\u201d\u003C\/p\u003E\u003Cp\u003EHSCs can also be modified directly inside the body. The procedure uses lipid nanoparticles (LNPs) to carry genetic instructions to the stem cells. The LNPs have targeting ligands attached \u2014 molecules designed to find specific target cells. Precisely engineering them adds layers of time, complexity, and cost to the process. They are, like extraction from bone marrow and chemotherapy, another middleman.\u003C\/p\u003E\u003Cp\u003EThe researchers wanted something simpler. They found it in a specific nanoparticle called LNP67.\u003C\/p\u003E\u003Cp\u003E\u201cUnlike other nanoparticle designs, this one doesn\u2019t require a targeting ligand,\u201d Dahlman said. \u201cIt\u2019s chemically simple, which means it\u2019s easier to manufacture and opens the door to eventually scaling production, like mRNA vaccines.\u201d\u003C\/p\u003E\u003Ch4\u003E\u003Cstrong\u003EOvercoming the Liver\u003C\/strong\u003E\u003C\/h4\u003E\u003Cp\u003EThe key to LNP67\u2019s success is its ability to dodge the liver, the body\u2019s primary blood filter. Foreign invaders, even helpful invaders delivered through an IV as medicine, can be captured by a healthy liver.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cThe liver absorbs almost everything,\u201d Dahlman said. \u201cBut, by reducing what it captures by even as little as 10 percent, we can double delivery to other tissues where the nanoparticles and their payloads are needed.\u201d\u003C\/p\u003E\u003Cp\u003EThe researchers developed 128 unique nanoparticles, narrowing the list down to 105 LNPs that didn\u2019t have targeting ligands. These were ultimately screened and evaluated for their performance in delivering genetic instructions (in the form of mRNA) effectively and safely.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ELNP67 emerged as the best performer thanks to its stealthy design. For example, the surface is designed to repel proteins and other molecules that would mark the LNP for capture by the liver. This feature helped the particles circulate more evenly in the body and reach the HSCs.\u003C\/p\u003E\u003Cp\u003E\u201cWe achieved low-dose delivery without a target ligand, which is exciting,\u201d Dahlman said. \u201cThis is something we\u2019ve been working toward for years, and I\u2019m very happy we got there.\u201d\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECitation:\u003C\/strong\u003E Hyejin Kim, Ryan Zenhausern, Kara Gentry, Liming Lian, Sebastian G. Huayamares, Afsane Radmand, David Loughrey, Ananda Podilapu, Marine Z. C. Hatit, Huanzhen Ni, Andrea Li, Aram Shajii, Hannah E. Peck, Keyi Han, Xuanwen Hua, Shu Jia, Michele Martinez, Charles Lee, Philip J. Santangelo, Alice Tarantal, James E. Dahlman. \u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41587-024-02470-2\u0022\u003ELipid Nanoparticle Study, Nov. 2024\u003C\/a\u003E, \u003Cem\u003ENature Biotechnology.\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EFunding:\u003C\/strong\u003E This research was supported by the National Institutes of Health grants UL1TR002378, UH3-TR002855, U42 OD027094, and TL1DK136047; National Science Foundation grant 0923395. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of any funding agency.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECompeting Interests:\u003C\/strong\u003E James Dahlman, Marine Z. C. Hatit, and Huanzhen Ni have filed a provisional patent related to this manuscript (US patent application number 63\/632,354).\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":[{"value":"Researchers demonstrate stem cell treatment without chemotherapy and painful bone marrow procedure"}],"field_summary":[{"value":"\u003Cp\u003EResearchers develop a lipid nanoparticle that can program stem cells while inside the body, avoiding the need for chemotherapy and bone marrow extraction in stem cell treatments.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Researchers develop nanoparticle that can program stem cells while inside the body, avoiding the need for chemotherapy and bone marrow extraction in stem cell treatments."}],"uid":"28153","created_gmt":"2024-12-21 12:43:16","changed_gmt":"2024-12-21 13:02:54","author":"Jerry Grillo","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2024-12-21T00:00:00-05:00","iso_date":"2024-12-21T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"675906":{"id":"675906","type":"image","title":"Lipid nanoparticle","body":"\u003Cp\u003ELipid nanoparticles in their element: This computer generated image shows lipid nanoparticles, which are used to transport payloads to targets inside the body.\u0026nbsp;\u003C\/p\u003E","created":"1734785517","gmt_created":"2024-12-21 12:51:57","changed":"1734785634","gmt_changed":"2024-12-21 12:53:54","alt":"Lipid nanoparticle AI generated image from adobe stock","file":{"fid":"259580","name":"Screen Shot 2024-12-17 at 12.14.01 PM.png","image_path":"\/sites\/default\/files\/2024\/12\/21\/Screen%20Shot%202024-12-17%20at%2012.14.01%20PM.png","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2024\/12\/21\/Screen%20Shot%202024-12-17%20at%2012.14.01%20PM.png","mime":"image\/png","size":9829642,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2024\/12\/21\/Screen%20Shot%202024-12-17%20at%2012.14.01%20PM.png?itok=g8m6iQ-v"}}},"media_ids":["675906"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"140","name":"Cancer Research"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"189917","name":"lipid nanoparticles"},{"id":"186748","name":"lipid nanoparticle"},{"id":"169030","name":"stem cell treatment"},{"id":"171013","name":"stem cell therapy"},{"id":"187915","name":"go-researchnews"},{"id":"187423","name":"go-bio"},{"id":"182868","name":"blood cells"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[{"id":"71891","name":"Health and Medicine"},{"id":"71881","name":"Science and Technology"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jerry.grillo@ibb.gatech.edu\u0022\u003EJerry Grillo\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["jerry.grillo@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"678608":{"#nid":"678608","#data":{"type":"news","title":" Semiconductor Research Corp. and Georgia Tech Secure $285M SMART USA Institute ","body":[{"value":"\u003Cdiv\u003E\u003Cp\u003E\u0026nbsp;The Department of Commerce has granted the Semiconductor Research Corporation (SRC), its partners, and Georgia Institute of Technology $285 million to establish and operate the 18th \u003Ca href=\u0022https:\/\/www.manufacturingusa.com\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EManufacturing USA Institute\u003C\/a\u003E. The \u003Ca href=\u0022https:\/\/www.src.org\/about\/smart-usa-institute\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003ESemiconductor Manufacturing and Advanced Reseach with Twins (SMART USA)\u003C\/a\u003E will focus on using digital twins to accelerate the development and deployment of microelectronics. SMART USA, with more than 150 expected partner entities representing industry, academia, and the full spectrum of supply chain design and manufacturing, will span more than 30 states and have combined funding totaling $1 billion.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThis is the first-of-its-kind CHIPS Manufacturing USA Institute.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cGeorgia Tech\u2019s role in the SMART USA Institute amplifies our trailblazing chip and advanced packaging research and leverages the strengths of our interdisciplinary research institutes,\u201d said \u003Ca href=\u0022https:\/\/research.gatech.edu\/people\/timothy-charles-lieuwen\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003ETim Lieuwen\u003C\/a\u003E, interim executive vice president for Research. \u201cWe believe innovation thrives where disciplines and sectors intersect. And the SMART USA Institute will help us ensure that the benefits of our semiconductor and advanced packaging discoveries extend beyond our labs, positively impacting the economy and quality of life in Georgia and across the United States.\u201d\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThe \u003Ca href=\u0022http:\/\/prc.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003E3D Systems Packaging Research Center\u003C\/a\u003E (PRC), directed by \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003ESchool of Electrical and Computer Engineering\u003C\/a\u003E Dan Fielder Professor \u003Ca href=\u0022https:\/\/research.gatech.edu\/people\/muhannad-s-bakir\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EMuhannad Bakir\u003C\/a\u003E, played an integral role in developing the winning proposal. Georgia Tech will be designated as the Digital Innovation Semiconductor Center (DISC) for the Southeastern U.S. \u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cWe are honored to collaborate with SRC and their team on this new Manufacturing USA Institute. Our partnership with SRC spans more than two decades, and we are thrilled to continue this collaboration by leveraging the Institute\u2019s wide range of semiconductor and advanced packaging expertise,\u201d said Bakir.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EThrough the \u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/core-facilities\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EInstitute of Matter and Systems\u2019\u003C\/a\u003E\u003Ca href=\u0022https:\/\/matter-systems.gatech.edu\/core-facilities\u0022\u003E core facilities\u003C\/a\u003E, housed in the \u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/marcus-nanotechnology-building\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EMarcus Nanotechnology Building\u003C\/a\u003E, DISC will accelerate semiconductor and advanced packaging development.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cThe awarding of the Digital Twin Manufacturing USA Institute is a culmination of more than three years of work with the Semiconductor Research Corporation and other valued team members who share a similar vision of advancing U.S. leadership in semiconductors and advanced packaging,\u201d said \u003Ca href=\u0022https:\/\/research.gatech.edu\/people\/george-white\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EGeorge White\u003C\/a\u003E, senior director for strategic partnerships at Georgia Tech.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cAs a founding member of the SMART USA Institute, Georgia Tech values this long-standing partnership. Its industry and academic partners, including the \u003Ca href=\u0022https:\/\/commerce.gov\/news\/blog\/2024\/02\/commerce-secretary-gina-raimondo-hosts-launch-hbcu-chips-network-build-skilled\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EHBCU CHIPS Network\u003C\/a\u003E, stand ready to make significant contributions to realize the goals and objectives of the SMART USA Institute,\u201d White added.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u0026nbsp;Georgia Tech also plans to capitalize on the supply chain and optimization strengths of the No. 1-ranked \u003Ca href=\u0022https:\/\/isye.gatech.edu\/\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003EH. Milton Stewart School of Industrial and Systems Engineering\u003C\/a\u003E (ISyE). ISyE experts will help develop supply-chain digital twins to optimize and streamline manufacturing and operational efficiencies.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003EDavid\u202fHenshall, SRC vice president of Business Development, said, \u201cThe SMART USA Institute will advance American digital twin technology and apply it to the full semiconductor supply chain, enabling rapid process optimization, predictive maintenance, and agile responses to chips supply chain disruptions. These efforts will strengthen U.S. global competitiveness, ensuring our country reaps the rewards of American innovation at scale.\u201d \u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/www.commerce.gov\/news\/press-releases\/2024\/11\/chips-america-announces-new-proposed-285-million-award-chips\u0022 rel=\u0022noreferrer noopener\u0022 target=\u0022_blank\u0022\u003ERead the full announcement from the Department of Commerce.\u003C\/a\u003E\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u003Cem\u003EThe award will help increase U.S. global competitiveness in semiconductor and advanced packaging research and manufacturing.\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"The award will help increase U.S. global competitiveness in semiconductor and advanced packaging research and manufacturing."}],"uid":"35272","created_gmt":"2024-11-22 19:39:38","changed_gmt":"2024-11-22 22:57:46","author":"aneumeister3","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2024-11-22T00:00:00-05:00","iso_date":"2024-11-22T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"675725":{"id":"675725","type":"image","title":"smart-usa-logo-tm-name-stamped.png","body":null,"created":"1732304385","gmt_created":"2024-11-22 19:39:45","changed":"1732304385","gmt_changed":"2024-11-22 19:39:45","alt":"SMART USA logo","file":{"fid":"259385","name":"smart-usa-logo-tm-name-stamped.png","image_path":"\/sites\/default\/files\/2024\/11\/22\/smart-usa-logo-tm-name-stamped.png","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2024\/11\/22\/smart-usa-logo-tm-name-stamped.png","mime":"image\/png","size":142392,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2024\/11\/22\/smart-usa-logo-tm-name-stamped.png?itok=iDKwRMd9"}}},"media_ids":["675725"],"groups":[{"id":"660369","name":"Matter and Systems"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"39451","name":"Electronics and Nanotechnology"},{"id":"193652","name":"Matter and Systems"},{"id":"39541","name":"Systems"}],"news_room_topics":[{"id":"71881","name":"Science and Technology"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:amelia.neumeister@research.gatech.edu\u0022\u003EAmelia Neumeister\u003C\/a\u003E | Research Communications Program Manager\u003C\/p\u003E","format":"limited_html"}],"email":["amelia.neumeister@research.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"676919":{"#nid":"676919","#data":{"type":"news","title":"Student Analog Chip Designs Come to Life Through New Collaboration with Texas Instruments","body":[{"value":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EWhether it is the sound of music through your headphones or the precise control of a robotic arm, analog circuits play a crucial role in both established and future technologies.\u003C\/p\u003E\u003Cp\u003EAnalog does a lot of things, but in general, it functions as the interpreter between the real world and digital devices. It transforms signals \u2014 like sound waves, voltage levels, temperature, pressure, and light intensity \u2014 into information that digital systems can understand.\u0026nbsp;\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EAs the semiconductor industry evolves, the demand for skilled analog engineers continues to grow even in this digital world.\u003C\/p\u003E\u003Cp\u003E\u201cAnalog circuits remain vital because they enable the initial data acquisition from the environment,\u201d said Assistant Professor \u003Ca href=\u0022https:\/\/ece.gatech.edu\/directory\/shaolan-li\u0022\u003E\u003Cstrong\u003EShaolan Li\u003C\/strong\u003E\u003C\/a\u003E. \u201cThat\u2019s just the application perspective, but they are also structurally very different than digital circuits. Students need hands-on experience with real-world measurements, which are crucial for mastering analog circuits.\u201d\u003C\/p\u003E\u003Cp\u003ETo meet this demand, the \u003Ca href=\u0022https:\/\/ece.gatech.edu\/\u0022\u003E\u003Cstrong\u003EGeorgia Tech School of Electrical and Computer Engineering\u003C\/strong\u003E\u003C\/a\u003E (ECE) is collaborating with \u003Ca href=\u0022https:\/\/www.ti.com\/\u0022 rel=\u0022noreferrer\u0022 title=\u0022(opens in a new window)\u0022\u003E\u003Cstrong\u003ETexas Instruments\u003C\/strong\u003E\u003C\/a\u003E (TI) to launch strategic educational opportunities aimed at providing students access to industry-grade analog chip design, fabrication, and testing processes. TI is a global semiconductor company that designs, manufactures, and sells analog and embedded processing chips.\u003C\/p\u003E\u003Ch3\u003E\u003Ca href=\u0022https:\/\/ece.gatech.edu\/analogchipnews\u0022\u003E\u003Cstrong\u003ERead the full article...\u003C\/strong\u003E\u003C\/a\u003E\u003C\/h3\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EStudents experience the real-world analog chip tapeout process, with their designs being produced at Texas Instruments\u2019 state-of-the-art wafer fabs.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Students experience the real-world analog chip tapeout process, with their designs being produced at Texas Instruments\u2019 state-of-the-art wafer fabs."}],"uid":"36172","created_gmt":"2024-09-18 14:45:08","changed_gmt":"2024-09-30 16:28:25","author":"dwatson71","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2024-09-18T00:00:00-04:00","iso_date":"2024-09-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"675008":{"id":"675008","type":"image","title":"1_ECE TI Analog_10_working on chip.jpg","body":"\u003Cdiv\u003E\u003Cp\u003ETzu-Han Wang working on a circuit board with an analog chip connected to pattern generator instruments used to create continuous waveforms to test and analyze the performance of the chip.\u003C\/p\u003E\u003C\/div\u003E","created":"1726670716","gmt_created":"2024-09-18 14:45:16","changed":"1726670716","gmt_changed":"2024-09-18 14:45:16","alt":"Tzu-Han Wang working on a circuit board with an analog chip connected to pattern generator instruments used to create continuous waveforms to test and analyze the performance of the chip.    ","file":{"fid":"258593","name":"1_ECE TI Analog_10_working on chip.jpg","image_path":"\/sites\/default\/files\/2024\/09\/18\/1_ECE%20TI%20Analog_10_working%20on%20chip.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2024\/09\/18\/1_ECE%20TI%20Analog_10_working%20on%20chip.jpg","mime":"image\/jpeg","size":5123597,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2024\/09\/18\/1_ECE%20TI%20Analog_10_working%20on%20chip.jpg?itok=jxsHu5o-"}}},"media_ids":["675008"],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"42911","name":"Education"},{"id":"145","name":"Engineering"},{"id":"129","name":"Institute and Campus"},{"id":"132","name":"Institute Leadership"},{"id":"149","name":"Nanotechnology and Nanoscience"}],"keywords":[{"id":"181277","name":"analog circuits"},{"id":"1470","name":"Texas Instruments"},{"id":"182039","name":"Shaolan Li"},{"id":"139771","name":"Arijit Raychowdhury"},{"id":"193959","name":"Tzu-Han Wang"},{"id":"193960","name":"curriculum collaboration"},{"id":"193966","name":"news to share"},{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"39451","name":"Electronics and Nanotechnology"},{"id":"39501","name":"People and Technology"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EDan Watson\u003C\/p\u003E","format":"limited_html"}],"email":["dwatson@ece.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"675091":{"#nid":"675091","#data":{"type":"news","title":"Nanowires Create Elite Warriors to Enhance T Cell Therapy","body":[{"value":"\u003Cp\u003EAdoptive T-cell therapy has revolutionized medicine. A patient\u2019s T-cells \u2014 a type of white blood cell that is part of the body\u2019s immune system \u2014 are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, or cancer cells.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ENow Georgia Tech bioengineer\u0026nbsp;\u003Ca href=\u0022https:\/\/singhlab.bme.gatech.edu\/\u0022\u003EAnkur Singh\u003C\/a\u003E and his research team have developed a method to improve this pioneering immunotherapy.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ETheir solution involves using nanowires to deliver therapeutic miRNA to T-cells. This new modification process retains the cells\u2019 na\u00efve state, which means they\u2019ll be even better disease fighters when they\u2019re infused back into a patient.\u003C\/p\u003E\u003Cp\u003E\u201cBy delivering miRNA in na\u00efve T cells, we have basically prepared an infantry, ready to deploy,\u201d Singh said. \u201cAnd when these na\u00efve cells are stimulated and activated in the presence of disease, it\u2019s like they\u2019ve been converted into samurais.\u201d\u003C\/p\u003E\u003Ch4\u003ELean and Mean\u003C\/h4\u003E\u003Cp\u003ECurrently in adoptive T-cell therapy, the cells become stimulated and preactivated in the lab when they are modified, losing their na\u00efve state. Singh\u2019s new technique overcomes this limitation. The approach is described in a\u0026nbsp;\u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41565-024-01649-7\u0022\u003Enew study\u003C\/a\u003E published in the journal \u003Cem\u003ENature Nanotechnology\u003C\/em\u003E.\u003C\/p\u003E\u003Cp\u003E\u201cNa\u00efve T-cells are more useful for immunotherapy because they have not yet been preactivated, which means they can be more easily manipulated to adopt desired therapeutic functions,\u201d said Singh, the Carl Ring Family Professor in the\u0026nbsp;\u003Ca href=\u0022https:\/\/www.me.gatech.edu\/\u0022\u003EWoodruff School of Mechanical Engineering\u003C\/a\u003E and the\u0026nbsp;\u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/\u0022\u003EWallace H. Coulter Department of Biomedical Engineering\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe raw recruits of the immune system, na\u00efve T-cells are white blood cells that haven\u2019t been tested in battle yet. But these cellular recruits are robust, impressionable, and adaptable \u2014 ready and eager for programming.\u003C\/p\u003E\u003Cp\u003E\u201cThis process creates a well-programmed na\u00efve T-cell ideal for enhancing immune responses against specific targets, such as tumors or pathogens,\u201d said Singh.\u003C\/p\u003E\u003Cp\u003EThe precise programming na\u00efve T-cells receive sets the foundational stage for a more successful disease fighting future, as compared to preactivated cells.\u003C\/p\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Ch4\u003E\u003Cstrong\u003EGiving Fighter Cells a Boost\u003C\/strong\u003E\u003C\/h4\u003E\u003Cp\u003EWithin the body, na\u00efve T-cells become activated when they receive a danger signal from antigens, which are part of disease-causing pathogens, but they send a signal to T-cells that activate the immune system.\u003C\/p\u003E\u003Cp\u003EAdoptive T-cell therapy is used against aggressive diseases that overwhelm the body\u2019s defense system. Scientists give the patient\u2019s T-cells a therapeutic boost in the lab, loading them up with additional medicine and chemically preactivating them.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThat\u2019s when the cells lose their na\u00efve state. When infused back into the patient, these modified T-cells are an effective infantry against disease \u2014 but they are prone to becoming exhausted. They aren\u2019t samurai. Na\u00efve T-cells, though, being the young, programmable recruits that they are, could be.\u003C\/p\u003E\u003Cp\u003EThe question for Singh and his team was: How do we give cells that therapeutic boost without preactivating them, thereby losing that pristine, highly suggestable na\u00efve state? Their answer: Nanowires.\u003C\/p\u003E\u003Ch4\u003E\u003Cstrong\u003ENanoPrecision: The Pointed Solution\u003C\/strong\u003E\u003C\/h4\u003E\u003Cp\u003ESingh wanted to enhance na\u00efve T-cells with a dose of miRNA. miRNA is a molecule that, when used as a therapeutic, works as a kind of volume knob for genes, turning their activity up or down to keep infection and cancer in check. The miRNA for this study was developed in part by the study\u2019s co-author, Andrew Grimson of Cornell University.\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003E\u201cIf we could find a way to forcibly enter the cells without damaging them, we could achieve our goal to deliver the miRNA into na\u00efve T cells without preactivating them,\u201d Singh explained.\u003C\/p\u003E\u003Cp\u003ETraditional modification in the lab involves binding immune receptors to T-cells, enabling the uptake of miRNA or any genetic material (which results in loss of the na\u00efve state). \u201cBut nanowires do not engage receptors and thus do not activate cells, so they retain their na\u00efve state,\u201d Singh said.\u003C\/p\u003E\u003Cp\u003EThe nanowires, silicon wafers made with specialized tools at Georgia Tech\u2019s\u0026nbsp;\u003Ca href=\u0022https:\/\/research.gatech.edu\/nano\u0022\u003EInstitute for Electronics and Nanotechnology\u003C\/a\u003E, form a fine needle bed. Cells are placed on the nanowires, which easily penetrate the cells and deliver their miRNA over several hours. Then the cells with miRNA are flushed out from the tops of the nanowires, activated, eventually infused back into the patient. These programmed cells can kill enemies efficiently over an extended time period.\u003C\/p\u003E\u003Cp\u003E\u201cWe believe this approach will be a real gamechanger for adoptive immunotherapies, because we now have the ability to produce T-cells with predictable fates,\u201d says Brian Rudd, a professor of immunology at Cornell University, and co-senior author of the study with Singh.\u003C\/p\u003E\u003Cp\u003EThe researchers tested their work in two separate infectious disease animal models at Cornell for this study, and Singh described the results as \u201ca robust performance in infection control.\u201d\u003C\/p\u003E\u003Cp\u003EIn the next phase of study, the researchers will up the ante, moving from infectious disease to test their cellular super soldiers against cancer and move toward translation to the clinical setting.\u0026nbsp; New funding from the Georgia Clinical \u0026amp; Translational Science Alliance is supporting Singh\u2019s research.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECITATION:\u003C\/strong\u003E\u0026nbsp;\u0026nbsp;Kristel J. Yee Mon, Sungwoong Kim, Zhonghao Dai, Jessica D. West, Hongya Zhu5, Ritika Jain, Andrew Grimson, Brian D. Rudd, Ankur Singh. \u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41565-024-01649-7\u0022\u003E\u201cFunctionalized nanowires for miRNA-mediated therapeutic programming of na\u00efve T cells,\u201d\u003C\/a\u003E \u003Cem\u003ENature Nanotechnology\u003C\/em\u003E.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EFUNDING:\u003C\/strong\u003E Curci Foundation, NSF (EEC-1648035, ECCS-2025462, ECCS-1542081), NIH (5R01AI132738-06, 1R01CA266052-01, 1R01CA238745-01A1, U01CA280984-01, R01AI110613 and U01AI131348).\u003C\/p\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u003Cem\u003EResearchers at Georgia Tech have developed a method using nanowires to deliver miRNA to T-cells, preserving their na\u00efve state and significantly enhancing their effectiveness in adoptive T-cell therapy for fighting infections and potentially cancer.\u003C\/em\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Researchers at Georgia Tech have developed a method using nanowires to deliver miRNA to T-cells, preserving their na\u00efve state and significantly enhancing their effectiveness in adoptive T-cell therapy for fighting infections and potentially cancer."}],"uid":"28153","created_gmt":"2024-06-12 14:09:49","changed_gmt":"2024-06-12 17:43:33","author":"Jerry Grillo","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2024-06-12T00:00:00-04:00","iso_date":"2024-06-12T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"674172":{"id":"674172","type":"image","title":"Ankur Singh","body":"\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cdiv\u003E\u003Cp\u003EAnkur Singh has developed a new way of programming T cells that retains their na\u00efve state, making them better fighters. \u2014 Photo by Jerry Grillo\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv\u003E\u0026nbsp;\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cp\u003E\u003Cbr\u003E\u003Cbr\u003E\u0026nbsp;\u003C\/p\u003E","created":"1718200954","gmt_created":"2024-06-12 14:02:34","changed":"1718201119","gmt_changed":"2024-06-12 14:05:19","alt":"Ankur Singh","file":{"fid":"257652","name":"ankur1.jpg","image_path":"\/sites\/default\/files\/2024\/06\/12\/ankur1.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2024\/06\/12\/ankur1.jpg","mime":"image\/jpeg","size":7331552,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2024\/06\/12\/ankur1.jpg?itok=aUhlcb_c"}},"674173":{"id":"674173","type":"image","title":"nanowires cells","body":"\u003Cp\u003EThis is an image of a T cell on a nanowire array. The arrow indicates where a nanowire has penetrated the cell, delivering therapeutic miRNA.\u003C\/p\u003E","created":"1718201149","gmt_created":"2024-06-12 14:05:49","changed":"1718201202","gmt_changed":"2024-06-12 14:06:42","alt":"Nanowires and cell","file":{"fid":"257653","name":"nanowire cell.jpg","image_path":"\/sites\/default\/files\/2024\/06\/12\/nanowire%20cell.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2024\/06\/12\/nanowire%20cell.jpg","mime":"image\/jpeg","size":158813,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2024\/06\/12\/nanowire%20cell.jpg?itok=cpBiHfWS"}}},"media_ids":["674172","674173"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"187915","name":"go-researchnews"},{"id":"187423","name":"go-bio"},{"id":"7074","name":"nanowires"},{"id":"179643","name":"T cell activation"},{"id":"9513","name":"Cancer Reserach"},{"id":"187433","name":"go-ien"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[{"id":"71891","name":"Health and Medicine"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EJerry Grillo\u003C\/p\u003E","format":"limited_html"}],"email":["Jerry.grillo@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}