Mild near-infrared laser activates genetic switch in T-cells in vitro

Mild near-infrared laser activates genetic switch in T-cells in vitro

Gentle pulses from a near-infrared laser hit gold nanorods, which warm up T-cells in in vitro tests, successfully activating a genetic switch implanted in the T-cells. Subsequent tests in vivo in mice with implanted phantom tumors confirmed massive gene expression triggered by the switch. Future experiments will be aimed at confirming cancer-fighting effectiveness. Credit: Georgia Tech / Allison Carter

Additional Information

Groups

News Room, Research Horizons

Categories
Research, Biotechnology, Health, Bioengineering, Genetics, Cancer Research, Engineering, Life Sciences and Biology, Nanotechnology and Nanoscience
Keywords
immunotherapy, near infrared laser, NIR, gold nanoparticles, gold nanorods, cancer, tumor, phantom tumor, genetic switch, heat sensitive, T-cell, T-cells, chemotherapy, cancer-fighting, Toxicity, heat shock, cytokines
Status
  • Created By: Ben Brumfield
  • Workflow Status: Published
  • Created On: Apr 18, 2018 - 12:31pm
  • Last Updated: Apr 19, 2018 - 5:02pm