{"605067":{"#nid":"605067","#data":{"type":"event","title":"Chemical \u0026 Biomolecular Engineering Seminar","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E3D Heterogeneous Architectures with Assembled Hydrogels and Cells on an Electromicrofluidic Platform\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EShih-Kang Fan\u003Cbr \/\u003E\r\nAssociate Professor\u003Cbr \/\u003E\r\nDepartment of Mechanical Engineering\u003Cbr \/\u003E\r\nNational Taiwan University\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EManufacturing of three-dimensional (3D) architectures through assembly of (1) prepolymer hydrogel droplets with suspended cells\/particles\/molecules and (2) crosslinked building blocks with reorganized embedded objects is demonstrated on an electromicrofluidic platform. The complex and heterogeneous 3D architectures are in great demand in various applications, including in the construction of artificial tissues that recapitulate physiological functions by imitating biological structures and in the production of novel metamaterials with properties atypical or nonexistent in nature. 3D hydrogel building blocks with reorganized cells or particles are formed and assembled on the electromicrofluidic platform adopting electrowetting and dielectrophoresis. We demonstrate the manipulations of varied objects (a) in multiple phases such as prepolymer liquid hydrogel droplets and crosslinked hydrogels, (b) on a wide range of scales from micrometer cells or particles to millimeter assembled hydrogel architectures, (c) with diverse properties such as conductive and dielectric prepolymer droplets that are photo, chemically, or thermally crosslinkable, and (d) in adjustable geometries including discrete droplets and continuous liquid columns. 3D hydrogel architectures, composed of varied particles or cells reorganized in programmable patterns and biomimetic hydrogels of designed properties and in adjustable geometries, are obtained. The electromicrofluidic platform is general and alternative to manipulate cells and hydrogel for reconfigurable 3D architectures.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u00223D Heterogeneous Architectures with Assembled Hydrogels and Cells on an Electromicrofluidic Platform\u0022 - Shih-Kang Fan, Ph.D. - National Taiwan University"}],"uid":"27349","created_gmt":"2018-04-13 14:38:39","changed_gmt":"2018-04-13 14:41:14","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2018-04-24T15:00:00-04:00","event_time_end":"2018-04-24T16:00:00-04:00","event_time_end_last":"2018-04-24T16:00:00-04:00","gmt_time_start":"2018-04-24 19:00:00","gmt_time_end":"2018-04-24 20:00:00","gmt_time_end_last":"2018-04-24 20:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:hang.lu@gatech.edu\u0022\u003EHang Lu\u003C\/a\u003E - faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}