{"604168":{"#nid":"604168","#data":{"type":"news","title":"Cell Sex Matters","body":[{"value":"\u003Cp\u003EBy Quinn Eastman,\u0026nbsp;Emory University\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EThe biological differences between male and female cells may influence their uptake of nanoparticles, which have been much discussed as specific delivery vehicles for medicines.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EVahid Serpooshan, a new faculty member of the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University, has a recent paper published in\u0026nbsp;\u003Ca href=\u0022https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.7b06212\u0022\u003E\u003Cem\u003EACS Nano\u003C\/em\u003E\u003C\/a\u003E\u0026nbsp;making this point. He and his colleagues from\u0026nbsp;\u003Ca href=\u0022https:\/\/www.eurekalert.org\/pub_releases\/2018-03\/bawh-fnc030818.php\u0022\u003EBrigham and Women\u0026rsquo;s Hospital\u003C\/a\u003E\u0026nbsp;and Stanford\/McGill\/UC Berkeley tested\u0026nbsp;amniotic stem cells, derived from placental tissue. They found that female amniotic cells had significantly higher uptake of nanoparticles (quantum dots) than male cells. The effect of cell sex on nanoparticle uptake was reversed in fibroblasts.\u0026nbsp;The researchers also found out that female\u0026nbsp;\u003Cem\u003Eversus\u003C\/em\u003E\u0026nbsp;male amniotic stem cells exhibited different responses to reprogramming into induced pluripotent stem cells (iPSCs).\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026ldquo;We believe this is a substantial discovery and a game changer in the field of nanomedicine, in taking safer and more effective and accurate steps towards successful clinical applications,\u0026rdquo; says Serpooshan, who is also part of the Department of Pediatrics at Emory.\u003C\/p\u003E\r\n\r\n\u003Cp\u003ESerpooshan\u0026rsquo;s interests lie in the realm of pediatric cardiology. His\u0026nbsp;\u003Ca href=\u0022https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=9205259\u0026amp;icde=38598882\u0022\u003EK99 grant\u003C\/a\u003E\u0026nbsp;indicates that he is planning to develop techniques for recruiting and activating cardiomyoblasts, via\u0026nbsp;\u0026ldquo;a bioengineered cardiac patch delivery of small molecules.\u0026rdquo;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003EBased at Emory, he joins labs with overlapping interests, such as Nawazish Naqvi\u0026rsquo;s, as well as \u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/faculty\/Michael-Davis\u0022\u003EMike Davis\u003C\/a\u003E and \u003Ca href=\u0022https:\/\/bme.gatech.edu\/bme\/faculty\/Hee%20Cheol-Cho\u0022\u003EHee Cheol Cho\u003C\/a\u003E, who are both researchers with the Petit Institute for Bioengineering and Bioscience in addition to being Coulter Department faculty members.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"Biological differences between male and female cells may influence nanomedicine "}],"field_summary":[{"value":"\u003Cp\u003EBiological differences between male and female cells may influence nanomedicine\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"Biological differences between male and female cells may influence nanomedicine "}],"uid":"28153","created_gmt":"2018-03-22 20:01:32","changed_gmt":"2018-03-22 20:03:15","author":"Jerry Grillo","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2018-03-22T00:00:00-04:00","iso_date":"2018-03-22T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"604166":{"id":"604166","type":"image","title":"Vahid Serpooshan","body":null,"created":"1521748519","gmt_created":"2018-03-22 19:55:19","changed":"1521748519","gmt_changed":"2018-03-22 19:55:19","alt":"","file":{"fid":"230302","name":"DSC_7044.JPG","image_path":"\/sites\/default\/files\/images\/DSC_7044.JPG","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/DSC_7044.JPG","mime":"image\/jpeg","size":3002999,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/DSC_7044.JPG?itok=rArMrJVe"}}},"media_ids":["604166"],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jerry.grillo@ibb.gatech.edu\u0022\u003EJerry Grillo\u003C\/a\u003E\u003Cbr \/\u003E\r\nCommunications Officer II\u003Cbr \/\u003E\r\nParker H. Petit Institute for\u003Cbr \/\u003E\r\nBioengineering and Bioscience\u003C\/p\u003E\r\n","format":"limited_html"}],"email":["Jerry.grillo@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}