{"48923":{"#nid":"48923","#data":{"type":"news","title":"Delivering Stem Cells Improves Repair of Major Bone Injuries in Rats","body":[{"value":"\u003Cp\u003EA study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.  \u003C\/p\u003E\n\u003Cp\u003EThe study shows that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation and better mechanical properties compared to treatment with the scaffold alone. This type of therapeutic treatment could be a potential alternative to bone grafting operations.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022Massive bone injuries are among the most challenging problems that orthopedic surgeons face, and they are commonly seen as a result of accidents as well as in soldiers returning from war,\u0022 said the study\u0027s lead author Robert Guldberg, a professor in Georgia Tech\u0027s Woodruff School of Mechanical Engineering. \u0022This study shows that there is promise in treating these injuries by delivering stem cells to the injury site. These are injuries that would not heal without significant medical intervention.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EDetails of the research were published in the early edition of the journal \u003Cem\u003EProceedings of the National Academy of Sciences\u003C\/em\u003E on January 11, 2010. This work was funded by the National Institutes of Health and the National Science Foundation.\n\u003C\/p\u003E\n\u003Cp\u003EThe study was conducted in rats in which two bone gaps eight millimeters in length were created to simulate massive injuries. One gap was treated with a polymer scaffold seeded with stem cells and the other with scaffold only. The results showed that injuries treated with the stem cell scaffolds showed significantly more bone growth than injuries treated with scaffolds only. \n\u003C\/p\u003E\n\u003Cp\u003EGuldberg and mechanical engineering graduate student Kenneth Dupont experimented with scaffolds containing two different types of human stem cells -- bone marrow-derived mesenchymal adult stem cells and amniotic fluid fetal stem cells. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022We were able to directly evaluate the therapeutic potential of human stem cells to repair large bone defects by implanting them into rats with a reduced immune system,\u0022 explained Guldberg, who is also the director of the Petit Institute for Bioengineering and Bioscience at Georgia Tech.\u003C\/p\u003E\n\u003Cp\u003EMicro-CT measurements showed no significant differences in bone regeneration between the two stem cell groups. However, combining the two types of stem cells produced significantly higher bone volume and strength compared to scaffolds without cellular augmentation.\n\u003C\/p\u003E\n\u003Cp\u003EAlthough stem cell delivery significantly enhanced bone growth and biomechanical properties, it was not able to consistently repair the injury. Eight weeks after the treatment, new bone bridged the gaps in four of nine defects treated with scaffolds seeded with adult stem cells, one of nine defects treated with scaffolds seeded with fetal stem cells, and none of the defects treated with the scaffold alone.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022We thought that the functional regeneration of the bone defects may have been limited by stem cells migrating away from the injury site, so we decided to investigate the fate and distribution of the delivered cells,\u0022 said Guldberg.\n\u003C\/p\u003E\n\u003Cp\u003ETo do this, Guldberg labeled stem cells with fluorescent quantum dots -- nanometer-scale particles that emit light when excited by near-infrared radiation -- to track the distribution of stem cells after delivery on the scaffolds and completed the same experiments as previously described. \n\u003C\/p\u003E\n\u003Cp\u003EThroughout the entire study, the researchers observed significant fluorescence at the stem cell scaffold sites. However, beginning seven to 10 days after treatment, signals appeared at the scaffold-only sites. Additional analysis with immunostaining revealed that the quantum dots present at the scaffold-only sites were contained in inflammatory cells called macrophages that had taken up quantum dots released from dead stem cells.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022While our overall study shows that stem cell therapy has a lot of promise for treating massive bone defects, this experiment shows that we still need to develop an improved way of delivering the stem cells so that they stay alive longer and thus remain at the injury site longer,\u0022 explained Guldberg.\u003C\/p\u003E\n\u003Cp\u003EThe researchers also found that the quantum dots diminished the function of the transplanted stem cells and thus their therapeutic effect. When the stem cells were labeled with quantum dots, the results showed a failure to enhance bone formation or bridge defects. However, the same low concentration of quantum dots did not affect cell viability or the ability of the stem cells to become bone cells in laboratory studies. \n\u003C\/p\u003E\n\u003Cp\u003E\u0022Although in vitro laboratory studies remain important, this work provides further evidence that well-characterized in vivo models are necessary to test the ability of regenerative tissue strategies to effectively integrate and restore function in complex living organisms,\u0022 added Guldberg. \u0022Improved methods of non-invasive cell tracking that do not alter cell function in vivo are needed to optimize stem cell delivery strategies and compare the effectiveness of different stem cell sources for tissue regeneration.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EGuldberg is currently exploring alternative cell tracking methods, such as genetically modifying the stem cells to express green fluorescent protein and\/or other luminescent enzymes such as luciferase. He is also investigating the addition of programming cues to the scaffold that will direct the stem cells to differentiate into bone cells. These signals may be particularly effective for fetal stem cells, which are believed to be more primitive than adult stem cells, according to Guldberg. \n\u003C\/p\u003E\n\u003Cp\u003ELessons learned from the current work are also being applied to develop effective stem cell therapies for severe composite injuries to multiple tissues including bone, nerve, vasculature and muscle. This follow-on work is being conducted in the Georgia Tech Center for Advanced Bioengineering for Soldier Survivability in collaboration with Ravi Bellamkonda and Barbara Boyan, professors in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.\n\u003C\/p\u003E\n\u003Cp\u003EOther authors on the paper include Andres Garcia, professor and Woodruff Faculty Fellow in Georgia Tech\u0027s Woodruff School of Mechanical Engineering and the Petit Institute for Bioengineering and Bioscience; Georgia Tech research scientist Hazel Stevens, Georgia Tech graduate student Joel Boerckel; and National University of Ireland medical student Kapil Sharma.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cem\u003EThis work was funded by grant number R01-AR051336 from the National Institutes of Health (NIH) and by grant number EEC-9731643 from the National Science Foundation (NSF). The content is solely the responsibility of the principal investigator and does not necessarily represent the official views of the NIH or NSF.\u003C\/em\u003E\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EResearch News \u0026amp; Publications Office\u003Cbr \/\u003E\nGeorgia Institute of Technology\u003Cbr \/\u003E\n75 Fifth Street, N.W., Suite 314\u003Cbr \/\u003E\nAtlanta, Georgia  30308  USA\n\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EMedia Relations Contacts:\u003C\/strong\u003E Abby Vogel (avogel@gatech.edu; 404-385-3364) or John Toon (jtoon@gatech.edu; 404-894-6986).\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EWriter:\u003C\/strong\u003E Abby Vogel\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"A new study published this week shows that delivering stem cells on a polymer scaffold to treat large areas of missing bone leads to improved bone formation and better mechanical properties compared to treatment with scaffold alone.","format":"limited_html"}],"field_summary_sentence":[{"value":"Study reinforces potential value of stem cells to repair bone in"}],"uid":"27206","created_gmt":"2010-01-11 01:00:00","changed_gmt":"2016-10-08 03:04:04","author":"Abby Vogel Robinson","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-01-11T00:00:00-05:00","iso_date":"2010-01-11T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"48924":{"id":"48924","type":"image","title":"Robert Guldberg bone regeneration","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Robert Guldberg bone regeneration","file":{"fid":"101291","name":"try39853.jpg","image_path":"\/sites\/default\/files\/images\/try39853_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/try39853_0.jpg","mime":"image\/jpeg","size":1255705,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/try39853_0.jpg?itok=qv-fHLYD"}},"48925":{"id":"48925","type":"image","title":"Bone regeneration with stem cell scaffold","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Bone regeneration with stem cell scaffold","file":{"fid":"101292","name":"tyd39853.jpg","image_path":"\/sites\/default\/files\/images\/tyd39853_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/tyd39853_0.jpg","mime":"image\/jpeg","size":405535,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tyd39853_0.jpg?itok=ZMJG3doK"}},"48926":{"id":"48926","type":"image","title":"Robert Guldberg bone regeneration","body":null,"created":"1449175408","gmt_created":"2015-12-03 20:43:28","changed":"1475894463","gmt_changed":"2016-10-08 02:41:03","alt":"Robert Guldberg bone regeneration","file":{"fid":"101293","name":"the39853.jpg","image_path":"\/sites\/default\/files\/images\/the39853_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/the39853_0.jpg","mime":"image\/jpeg","size":1050118,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/the39853_0.jpg?itok=VAKE7nTl"}}},"media_ids":["48924","48925","48926"],"related_links":[{"url":"http:\/\/www.me.gatech.edu\/faculty\/guldberg.shtml","title":"Robert Guldberg"},{"url":"http:\/\/www.me.gatech.edu\/","title":"George W. Woodruff School of Mechanical Engineering"},{"url":"http:\/\/www.ibb.gatech.edu\/","title":"Petit Institute for Bioengineering and Bioscience"}],"groups":[{"id":"1188","name":"Research Horizons"}],"categories":[{"id":"145","name":"Engineering"},{"id":"135","name":"Research"}],"keywords":[{"id":"8233","name":"amniotic fluid fetal stem cells"},{"id":"530","name":"bone"},{"id":"8227","name":"bone defect"},{"id":"8231","name":"Bone Marrow Derived Stem Cells"},{"id":"8226","name":"Bone Regeneration"},{"id":"8225","name":"Bone Repair"},{"id":"8232","name":"fetal stem cells"},{"id":"6891","name":"fluorescence"},{"id":"8230","name":"Mesenchymal Stem Cells"},{"id":"8228","name":"Orthopedics"},{"id":"8229","name":"polymer scaffold"},{"id":"2363","name":"quantum dots"},{"id":"1489","name":"Regenerative Medicine"},{"id":"167413","name":"Stem Cell"},{"id":"167139","name":"Stem Cell Research"},{"id":"167130","name":"Stem Cells"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EAbby Vogel\u003C\/strong\u003E\u003Cbr \/\u003EResearch News and Publications\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=avogel6\u0022\u003EContact Abby Vogel\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-3364\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"email":["avogel@gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"57723":{"#nid":"57723","#data":{"type":"news","title":"Engineering Inducts Some of Its Finest","body":[{"value":"\u003Cp\u003EOver 200 people attended the 2010 College of Engineering Induction Awards Ceremony on Friday, March 19 at the Georgia Tech Hotel and Conference Center Ballroom.  Addressing the guests and honorees were Dean Don Giddens, C. Dean Alford, Chair of the Engineering Advisory Board, and Stephen E. Cross, newly appointed Executive Vice President for Research.  Barbara Boyan, Associate Dean for Research was the \u0022master of ceremonies.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EGreen Theme\u003C\/strong\u003E\n\u003C\/p\u003E\n\u003Cp\u003EThe theme of the evening\u0027s event was sustainability and it was the first \u0022green\u0022 event hosted by the College. Among the honored guests, 13 were inducted into the Council of Outstanding Young Engineers, 18 into the Academy of Distinguished Engineers, three into the Engineering Hall of Fame, and one individual was given an Honorary Engineering Award.  The names of these honored recipients are listed below.\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003EAccolades from the Dean\u003C\/strong\u003E\n\u003C\/p\u003E\n\u003Cp\u003E\u0022The College of Engineering places a great deal of emphasis on quality and innovation\u0022 said Dean Don Giddens, a past recipient of the Academy of Distinguished Engineering Alumni Award in 1994, \u0022and those honored at this event are true role models for future generation of engineers who demonstrate a solid technological Georgia Tech education, a competitive spirit, and drive for excellence.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003E2010 Council of Outstanding Young Engineering Alumni\u003C\/strong\u003E\n\u003C\/p\u003E\n\u003Cp\u003EKeefe Bohannan, EE \u002795\u003Cbr \/\u003E\nElizabeth Boltz, ME \u002791\u003Cbr \/\u003E\nAngela Gill Folsom, BME \u002707\u003Cbr \/\u003E\nEric Gebhardt, AE \u002790\u003Cbr \/\u003E\nSara N. Johnson, TFE \u002700\u003Cbr \/\u003E\nJoy Jordan, ChBE \u002792\u003Cbr \/\u003E\nTimothy Langlais, ChE \u002705\u003Cbr \/\u003E\nVivek Maddala, BEE \u002795\u003Cbr \/\u003E\nSean McClenaghan, ChE \u002787\u003Cbr \/\u003E\nParika Petaipimol, BME \u002704\u003Cbr \/\u003E\nJosh E. Rowen, CE \u002796\u003Cbr \/\u003E\nMary A. Spio, MS EE \u002799\u003Cbr \/\u003E\nBryan M. Swarn, PFE \u002703\n\u003C\/p\u003E\n\u003Cp\u003E\u003Cstrong\u003E2010 Academy of Distinguished Engineering Alumni\u003C\/strong\u003E\n\u003C\/p\u003E\n\u003Cp\u003EMichael Burnside, ME \u002774\u003Cbr \/\u003E\nRoland G. Caldwell, Jr., EE \u002788\u003Cbr \/\u003E\nDavid A. Dullum, ME \u201970\u003Cbr \/\u003E\nCharles L. Harris, IE \u201981\u003Cbr \/\u003E\nChristopher Hobson, ChE \u002779\u003Cbr \/\u003E\nJay D. Humphrey, ESM \u201982, \u002785\u003Cbr \/\u003E\nStephen F. Jensen,  CE\u201981\u003Cbr \/\u003E\nSusan Deal Kirchoff, CerE \u002780\u003Cbr \/\u003E\nGregory J. Koch, CE \u201990, MSCE \u002792\u003Cbr \/\u003E\nRobert D. Martin, IE \u002769\u003Cbr \/\u003E\nStephen M. Mitchell, IE \u201965, MS IE \u002767\u003Cbr \/\u003E\nTed R. Meinhofer, Text \u002794\u003Cbr \/\u003E\nThomas J. O\u2019Brien, IE \u201981\u003Cbr \/\u003E\nDavid Phelps, ME \u002781\u003Cbr \/\u003E\nRandall E. Poliner, BEE \u002777\u003Cbr \/\u003E\nPedro A. Ray,  EE \u201982, \u002783\u003Cbr \/\u003E\nGilberto Sarfaty, EES \u002781\u003Cbr \/\u003E\n2010 Engineering Alumni Hall of Fame\u003Cbr \/\u003E\nM. Andrew Clark, CerE \u002759\u003Cbr \/\u003E\nWilliam R. T. Oakes, Jr., AE \u002759\u003Cbr \/\u003E\nRichard H. Truly, AE \u002759\u003Cbr \/\u003E\n2010 Honorary Engineering Award\u003Cbr \/\u003E\nGeorge (Roy) L. Bowen III\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Over 200 people attended the 2010 College of Engineering Induction Awards Ceremony on Friday, March 19th at the GT Hotel and Conference Center Ballroom.","format":"limited_html"}],"field_summary_sentence":[{"value":"Engineering Inducts Some of Its Finest"}],"uid":"27195","created_gmt":"2010-06-01 00:00:00","changed_gmt":"2016-10-08 03:06:39","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2010-03-19T00:00:00-04:00","iso_date":"2010-03-19T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"140","name":"Cancer Research"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"149","name":"Nanotechnology and Nanoscience"},{"id":"135","name":"Research"}],"keywords":[{"id":"8016","name":"CoE"},{"id":"594","name":"college of engineering"},{"id":"109","name":"Georgia Tech"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"47478":{"#nid":"47478","#data":{"type":"news","title":"Executive VP for Research Search Committee Named","body":[{"value":"\u003Cp\u003EAs part of the senior academic leadership restructuring \u003Ca href=\u0022http:\/\/www.gatech.edu\/president\/lettersbulletins\/bulletin111709.html\u0022\u003Eannounced last month\u003C\/a\u003E, President Bud Peterson has formed a search committee to identify the individual who will oversee Georgia Tech\u0027s substantial research enterprise.\n\n\u003C\/p\u003E\u003Cp\u003EThe newly created executive vice president for research (EVPR) will report directly to the president and serve as a member of the president\u0027s cabinet. \n\n\u003C\/p\u003E\u003Cp\u003EThe office will have overall responsibility for all research at Georgia Tech - faculty-based research as well as research conducted at GTRI and the Enterprise Innovation Institute - representing almost one-half of Georgia Tech\u0027s budget. College of Sciences Dean Paul Houston will chair the search committee.\n\n\u003C\/p\u003E\u003Cp\u003EIn order for this individual to be in place prior to interviews with candidates for the provost position, the committee intends to conduct an internal search for the EVPR position, with the goal of having someone in place by March 2010. That committee includes:\u003C\/p\u003E\u003Cul\u003E\u003Cli\u003ERon Arkin, Professor and Associate Dean, College of Computing\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EBarbara Boyan, Professor and Associate Dean, College of Engineering\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EJorge Breton, Program Manager, Academic Affairs\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EBaruch Feigenbaum, Graduate Student\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EDennis Folds, Principal Research Scientist, Georgia Tech Research Institute\u0026nbsp;\u003C\/li\u003E\u003Cli\u003ESteve French, Professor and Associate Dean, College of Architecture\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EJilda Garton, Associate Vice Provost, Research\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EJoel Hercik, Associate Vice President, Financial Services\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EDiana Hicks, Professor and Chair, School of Public Policy\u0026nbsp;\u003C\/li\u003E\u003Cli\u003ERobert Knotts, Director, Federal Relations\u0026nbsp;\u003C\/li\u003E\u003Cli\u003ESeth Marder, Professor, School of Chemistry and Biochemistry\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EBill Melvin, Director, Sensors and Electromagnetic Applications Lab\u0026nbsp;\u003C\/li\u003E\u003Cli\u003ESandra Slaughter, Professor, College of Management\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EVigor Yang, Professor and Chair, School of Aerospace Engineering\u0026nbsp;\u003C\/li\u003E\u003Cli\u003EChuck Donbaugh, Associate Vice President, Human Resources (ex officio)\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u0022Our goal in forming this committee was to bring together a diverse group of interests, and I want to thank each member of the committee for serving the Institute in this capacity,\u0022 Houston said. \u0022The executive vice president will be entrusted with managing Georgia Tech\u0027s research enterprise and will benefit from broad-based support within our research community.\u0022\u003C\/p\u003E\u003Cp\u003EThe committee hopes to hold its first meeting later this month. Nominations, recommendations, and comments may be directed to Dr. Houston.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":[{"value":"A new position with overall responsibility for all research at Georgia Tech"}],"field_summary":[{"value":"As part of the senior academic leadership restructuring announced last month, President Bud Peterson has formed the search committee to identify the individual who will oversee Georgia Tech\u0027s substantial research enterprise.","format":"limited_html"}],"field_summary_sentence":"","uid":"27299","created_gmt":"2009-12-07 10:55:31","changed_gmt":"2016-10-08 03:03:49","author":"Michael Hagearty","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-12-07T00:00:00-05:00","iso_date":"2009-12-07T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"41360":{"id":"41360","type":"image","title":"Tech Tower","body":null,"created":"1449174301","gmt_created":"2015-12-03 20:25:01","changed":"1475894368","gmt_changed":"2016-10-08 02:39:28"}},"media_ids":["41360"],"related_links":[{"url":"http:\/\/www.gatech.edu\/president\/","title":"Georgia Tech President G.P. (Bud) Peterson"},{"url":"http:\/\/www.gatech.edu\/president\/EVPR.html","title":"EVPR Position Summary"}],"groups":[{"id":"1182","name":"General"}],"categories":[{"id":"129","name":"Institute and Campus"}],"keywords":[{"id":"7849","name":"cabinet"},{"id":"7850","name":"EVPR"},{"id":"1271","name":"President"},{"id":"365","name":"Research"},{"id":"169394","name":"Search Committee"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:paul.houston@cos.gatech.edu\u0022\u003EPaul Houston\u003C\/a\u003E\u003Cbr \/\u003ECollege of Sciences\u0026nbsp;\u003Cbr \/\u003E404-894-3300\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}},"56406":{"#nid":"56406","#data":{"type":"news","title":"Labs report progress in regrowing bones","body":[{"value":"\u003Cp\u003EATLANTA \u2014 As military doctors in Iraq and Afghanistan have seen more horrific injuries involving skin, nerve, vascular and bone losses from explosions, they have tried to think of what more could be done for the victims besides bandaging things up and hoping for the best.\n\u003C\/p\u003E\n\u003Cp\u003EMaybe they could regrow the tissue: Grow the cartilage, grow the blood vessels, grow the nerves and even grow the bone. \n\u003C\/p\u003E\n\u003Cp\u003E\u003Ca href=\u0027http:\/\/www.armytimes.com\/news\/2009\/10\/marine_bone_101109w\/\u0027\u003EView full article\u003C\/a\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"ATLANTA \u2014 As military doctors in Iraq and Afghanistan have seen more horrific injuries involving skin, nerve, vascular and bone losses from explosions, they have tried to think of what more could be done for the victims besides bandaging things up and hoping for the best.","format":"limited_html"}],"field_summary_sentence":[{"value":"Labs report progress in regrowing bones"}],"uid":"27224","created_gmt":"2009-10-12 00:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Megan McDevitt","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-10-12T00:00:00-04:00","iso_date":"2009-10-12T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"535","name":"boyan"},{"id":"6973","name":"Guldberg"},{"id":"9524","name":"orthopedic"},{"id":"167413","name":"Stem Cell"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EMegan McDevitt\u003C\/strong\u003E\u003Cbr \/\u003EIBB\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=mm504\u0022\u003EContact Megan McDevitt\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-385-7001\u003C\/strong\u003E","format":"limited_html"}],"email":["megan.mcdevitt@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56453":{"#nid":"56453","#data":{"type":"news","title":"GT launches center to improve recovery of severely injured soldiers","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u003Cem\u003ELocal Tech Wire - June 25, 2009\u003C\/em\u003E\u003C\/strong\u003E\u003Cbr \/\u003E\nWhen a soldier is wounded during combat, surgeons must focus on reducing infection and reconstructing damaged bone and tissues. Technologies that could improve the repair and regeneration processes are being developed in research laboratories across the country, but they are not being moved quickly enough into military trauma centers.  Organizers of the recently established Georgia Tech Center for Advanced Bioengineering for Soldier Survivability want to change that.  \u0022The goal of the center is to rapidly move new technologies from the laboratory to patients so that we can improve the quality of life for our veterans as they return from the wars the United States is fighting,\u0022 said center director Barbara Boyan, the Price Gilbert, Jr. Chair in Tissue Engineering at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. \n\u003C\/p\u003E\n\u003Cp\u003EView full article:  \u003Ca href=\u0027http:\/\/localtechwire.com\/business\/local_tech_wire\/venture\/story\/5432514\/\u0027\u003ESoldier Survivability\u003C\/a\u003E\n\u003C\/p\u003E\n\u003Cp\u003EFor more information on Barbara Boyan lab, visit:  \u003Ca href=\u0027http:\/\/www.bme.gatech.edu\/facultystaff\/faculty_record.php?id=48\u0027\u003EBoyan Laboratory\u003C\/a\u003E\n\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"When a soldier is wounded during combat, surgeons must focus on reducing infection and reconstructing damaged bone and tissues. Organizers of the recently established Georgia Tech Center for Advanced Bioengineering for Soldier Survivability want to change that.","format":"limited_html"}],"field_summary_sentence":[{"value":"GT launches center to improve recovery of severely injured soldi"}],"uid":"27195","created_gmt":"2009-07-06 00:00:00","changed_gmt":"2016-10-08 03:06:11","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2009-06-25T00:00:00-04:00","iso_date":"2009-06-25T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"134","name":"Student and Faculty"},{"id":"145","name":"Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"}],"keywords":[{"id":"9548","name":"Barbara Boyan"},{"id":"569","name":"bioengineering"},{"id":"109","name":"Georgia Tech"},{"id":"170977","name":"Soldier Survivability"},{"id":"9553","name":"Wallace H. Coulter"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"56378":{"#nid":"56378","#data":{"type":"news","title":"Dr. Boyan and Ms. Chen 07 Women of Distinction","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EBarbara Boyan\u003C\/strong\u003E\u003Cbr \/\u003E\nAfter receiving her B.A. in Biology at Rice University, Barbara went on to earn her Ph.D. in Comparative Biochemistry and Physiology at Rice in 1975. Dr. Boyan is now a professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University in Atlanta, Georgia, where she holds the Price Gilbert, Jr. Chair in Tissue Engineering. She is also an adjunct professor in the Departments of Orthopaedics and Cell Biology at Emory University Medical School as well as the Schools of Biology and Materials Science and Engineering at the Georgia Institute of Technology, and she has an adjunct professorship in Periodontics at the University of Texas Health Science Center at San Antonio. Dr. Boyan is a Georgia Research Alliance Eminent Scholar and Deputy Director of Research at the Georgia Tech-Emory Center for the Engineering of Living Tissue.\n\u003C\/p\u003E\n\u003Cp\u003EDr. Boyan has demonstrated collaborative leadership in the emerging interdisciplinary field of tissue engineering in both academic and business domains. Dr. Boyan co-chairs the Preclinical Assessments subcommittee of the Tissue Engineered Medical Products F04 Division of ASTM. She has served as chair of the Orthopaedic Device Panel of the United States Food and Drug Administration and presently serves on the National Materials Advisory Board for the National Academies in the United States.  Dr. Boyan also presently serves on the Boards of Directors of two NASDAQ companies: ArthroCare, Inc., and IsoTis, Inc., an orthobiologics company. In 1993, she co-founded OsteoBiologics, Inc. to develop tissue engineered medical products for treatment of bone and cartilage defects. The first generation of these products is now approved for use clinically both in the US and Europe and OsteoBiologics has been acquired by Smith \u0026amp; Nephew, Inc., an international medical device company. Dr. Boyan is also founder of Biomedical Development Corporation and Orthonics, Inc., which was recently acquired by Carticept Medical, Inc. In 2007, she co-founded SpherIngenics, Inc., which is developing technology invented at Georgia Tech.\n\u003C\/p\u003E\n\u003Cp\u003EHer research program is focused on bone and cartilage cell biology in the fields of orthopaedics and oral health. The author of more than 340 peer-reviewed papers, reviews, and book chapters, Dr. Boyan holds eight U.S. and international patents. She received the 2002 Clemson Award for Contributions to the Literature from the Society for Biomaterials for her research into cell response to material surfaces such as those used in implants and tissue engineering. She is particularly well known for her advancements in the area of rapid responses to steroid hormones; our understanding of how biomaterials affect cell and tissue behavior; and our recognition that inherent differences in cells from male and female donors may have a significant impact on the development of effective cell-based therapies.\n\u003C\/p\u003E\n\u003Cp\u003EDr. Boyan has been instrumental in encouraging numerous women and men in their pursuit of academic and scientific careers. Her curriculum vita includes an impressive list of current and former advisees, and she has mentored and advised countless other undergraduate and graduate students, post doctoral fellows, and junior faculty. In 2000, she was recognized with the American Association for Dental Research Student Research Group Mentor Award. In addition, she promotes science and science education through her active participation in groups such as Leadership Texas and Leadership America, and she was the 2005 recipient of Atlanta Woman Magazine\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Each year at the Women\u0027s Leadership Conference, Georgia Tech honors women who demonstrate exemplary leadership abilities. Dr. Barbara Boyan received the honor for the Outstanding Faculty Member category and Ms. Inn-Inn Chen for the Outstanding Undergraduate Student category. Congratulations to the 2007 Women Of Distinction!","format":"limited_html"}],"field_summary_sentence":[{"value":"Dr. Boyan and Ms. Chen"}],"uid":"27195","created_gmt":"2007-12-14 01:00:00","changed_gmt":"2016-10-08 03:06:06","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2007-11-02T00:00:00-04:00","iso_date":"2007-11-02T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"56379":{"id":"56379","type":"image","title":"Dr. Benkeser presents Women of Distinction Award t","body":null,"created":"1449175629","gmt_created":"2015-12-03 20:47:09","changed":"1475894499","gmt_changed":"2016-10-08 02:41:39","alt":"Dr. Benkeser presents Women of Distinction Award t","file":{"fid":"190460","name":"tmt44220.jpg","image_path":"\/sites\/default\/files\/images\/tmt44220_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/tmt44220_0.jpg","mime":"image\/jpeg","size":37616,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tmt44220_0.jpg?itok=JI0nr5vd"}}},"media_ids":["56379"],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"132","name":"Institute Leadership"},{"id":"134","name":"Student and Faculty"},{"id":"135","name":"Research"}],"keywords":[{"id":"101","name":"Award"},{"id":"9498","name":"Distinction"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EColly Mitchell\u003C\/strong\u003E\u003Cbr \/\u003EParker H. Petit Institute for Bioengineering and Bioscience\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=cmitchell6\u0022\u003EContact Colly Mitchell\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-5982\u003C\/strong\u003E","format":"limited_html"}],"email":["colly.mitchell@ibb.gatech.edu"],"slides":[],"orientation":[],"userdata":""}},"40614":{"#nid":"40614","#data":{"type":"news","title":"Georgia Tech Student Wins Marshall Scholarship","body":[{"value":"\u003Cp\u003EAmbika Bumb knows firsthand about the importance of technology in medicine. As an intern at GE Healthcare last summer, she helped her team diagnose and repair a problem that caused new blood pressure monitors at Children\u0027s Hospital of Philadelphia to take more than 10 minutes to get a reading - time that could mean the difference between life and death in an emergency room.\n\u003C\/p\u003E\n\u003Cp\u003E The experience reinforced Bumb\u0027s commitment to developing life-saving medical technologies. She\u0027ll continue to chase her dream next fall at Oxford where she\u0027ll pursue a Ph.D. in medical engineering as a recipient of a 2005 Marshall Scholarship.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022This may sound idealistic,\u0022 said Bumb, \u0022but I want to help come up with a new technology or treatment for a disease. I want to be the person who follows it through to make sure it reaches the people I\u0027m developing it for,\u0022 she said.\n\u003C\/p\u003E\n\u003Cp\u003EBumb said she knows medical treatments won\u0027t help anyone if they can\u0027t be commercially viable. \u0022You have to tailor the research to the market,\u0022 she said. \u0022For example, you develop drugs for Africa, not treatments that require lots of machines.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EA senior in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, Bumb plans to get her degree this spring, just three years after she enrolled on a Reginald S. Fleet President\u0027s Scholarship. \u0022Being at Georgia Tech has changed what my future is going to be. It\u0027s offered me so many opportunities and the President\u0027s Scholarship gave me the opportunity to be at Tech,\u0022 she said.\n\u003C\/p\u003E\n\u003Cp\u003EWhile at Tech, Bumb worked with associate professor Gang Bao on developing nanomolecular beacon tracking devices to map the territory of cells. This year, she\u0027s extending this research by designing a new tracking tool, a quantum dot, for vitamin D in the lab of professor Barbara Boyan. The quantum dot could be used to help treat bone and cartilage diseases such as osteoporosis and rickets.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022She\u0027s a natural leader and very insightful,\u0022 said Boyan. \u0022I have been struck by her systematic approach and her willingness to put in the hours necessary to tackle the problem in an organized and quite innovative way.\u0022\n\u003C\/p\u003E\n\u003Cp\u003EBumb said academics aren\u0027t the only thing to get out of college. At Tech she served on the Georgia Tech Advisory Board, working with prominent business leaders to advise the administration on future goals. She also served in student government on the Joint Finance Committee, helping to decide how to allocate $3.5 million collected from the student activities fee.\n\u003C\/p\u003E\n\u003Cp\u003E\u0022The finance committee was a huge learning experience in how to take resources to benefit the most people that you can,\u0022 she said.\n\u003C\/p\u003E\n\u003Cp\u003EIn addition, she helped found a new Indian dance team at Tech, Nazaaqat, which played to a packed house at the Ferst Center for the Arts.\n\u003C\/p\u003E\n\u003Cp\u003EBumb is the sixth Georgia Tech student to win the Marshall, a scholarship established by the British Government for American students in 1953 in appreciation for assistance received after World War II under the Marshall Plan. The scholarship encourages potential leaders to become ambassadors for the United States and establish personal ties between the two countries.\n\u003C\/p\u003E\n\u003Cp\u003EProminent former Marshall scholars include U.S. Supreme Court Justice Stephen Breyer; former U.S. Secretary of the Interior Bruce Babbitt; New York Times foreign affairs columnist Tom Friedman; and the scientist\/inventor Ray Dolby.\n\u003C\/p\u003E\n\u003Cp\u003EBumb said she hopes someday to fill the shoes of the Marshall Scholars who came before her. \u0022Like most kids, when I was little I had dreams of saving the world - inventing a cure or finding the key to world peace,\u0022 she said. \u0022However as you get older everyone around you becomes more realistic and you push off idealism for practicality. Now I have returned to that childhood fantasy, actually seeing that there may be a chance of me being able to make an impact on the world in some way.\u0022\n\u003C\/p\u003E\n\u003Cp\u003E\u003C\/p\u003E\n\u003Cp\u003E\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Ambika Bumb is committed to developing life-saving medical technologies. She\u0027ll continue to chase her dream next fall at Oxford where she\u0027ll pursue a Ph.D. in medical engineering as a recipient of a 2005 Marshall Scholarship.","format":"limited_html"}],"field_summary_sentence":[{"value":"Ambika Bumb is the sixth Tech student to win honor"}],"uid":"27310","created_gmt":"2004-12-02 01:00:00","changed_gmt":"2016-10-08 03:01:05","author":"David Terraso","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2004-12-02T00:00:00-05:00","iso_date":"2004-12-02T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"hg_media":{"40615":{"id":"40615","type":"image","title":"Ambika Bumb","body":null,"created":"1449174220","gmt_created":"2015-12-03 20:23:40","changed":"1475894220","gmt_changed":"2016-10-08 02:37:00","alt":"Ambika Bumb","file":{"fid":"189533","name":"tmr98404.jpg","image_path":"\/sites\/default\/files\/images\/tmr98404_1.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/tmr98404_1.jpg","mime":"image\/jpeg","size":601419,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/tmr98404_1.jpg?itok=d0TU7sVJ"}}},"media_ids":["40615"],"related_links":[{"url":"http:\/\/www.coe.gatech.edu\/academics\/units\/bme\/","title":"Georgia Tech\/Emory Department of Biomedical Engineering"},{"url":"http:\/\/www.psp.gatech.edu\/","title":"Georgia Tech President\\\u0027s Scholar Program"},{"url":"http:\/\/www.marshallscholarship.org\/","title":"Marshall Scholar"}],"groups":[{"id":"1183","name":"Home"}],"categories":[{"id":"129","name":"Institute and Campus"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"3281","name":"Ambika"},{"id":"3282","name":"Bumb"},{"id":"3280","name":"Marshall Scholar"},{"id":"3279","name":"Marshall Scholarship"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGeorgia Tech Media Relations\u003C\/strong\u003E\u003Cbr \/\u003ELaura Diamond\u003Cbr \/\u003E\u003Ca href=\u0022mailto:laura.diamond@comm.gatech.edu\u0022\u003Elaura.diamond@comm.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-894-6016\u003Cbr \/\u003EJason Maderer\u003Cbr \/\u003E\u003Ca href=\u0022mailto:maderer@gatech.edu\u0022\u003Emaderer@gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-660-2926\u003C\/p\u003E","format":"limited_html"}],"email":["david.terraso@comm.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}