{"599203":{"#nid":"599203","#data":{"type":"event","title":"IEN Research Focus Seminar - Microneedles to Monitor Health and Human Performance","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EIEN Research Focus Seminar - Microneedles to Monitor Health and Human Performance\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003ERonen Polsky - Sandia National Laboratories, Department of Nano and Micro Sensors\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E We are exploring the prospect of using microneedles to access biomarkers for monitoring exposure to chemical and biological weapons. The development of an on-body diagnostic platform that can continuously monitor physiological markers in real-time will allow early warning capabilities that can signal an exposure event even prior to the onset of symptoms. We will present results on the development of a wearable transdermal diagnostic device to monitor lactate. A microfluidic device, based on microneedles, is being fabricated which can be worn on an individual and can painlessly access biological fluid (e.g., blood and\/or interstitial fluid) through the skin for real-time, long-term autonomous diagnostics of health and fitness. From our currently sponsored DTRA project, we have developed non-destructive interstitial fluid extraction methods that do not rely on blister formation, vacuum, or microdialysis. As we avoid methods that may change the native interstitial fluid content, we have enabled studies to determine baseline correlations between interstitial fluid and blood biomarkers. We have also found that exosomes are highly prevalent in interstitial fluid and will show preliminary results for genomic and proteomic analysis of the fluid.\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EBio:\u003C\/strong\u003E Dr. Polsky finished his PhD in 2004 at New Mexico State University with Joseph Wang and after a post-doctoral fellowship at the Hebrew University of Jerusalem under Itamar Willner joined Sandia National Laboratories in 2006. He is currently a Principal Member of Technical Staff in the Department of Nano and Micro Sensors with extensive expertise in biosensors and bioelectronics, surface chemistry, advanced fabrication, and novel nanomaterials. He currently leads a program on microneedle sensors.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"We will present results on the development of a wearable transdermal diagnostic device to monitor lactate. A microfluidic device, based on microneedles, is being fabricated which can be worn on an individual and can painlessly access biological fluid."}],"uid":"27863","created_gmt":"2017-11-28 16:27:31","changed_gmt":"2017-11-28 16:28:14","author":"Christa Ernst","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2018-01-18T10:30:00-05:00","event_time_end":"2018-01-18T11:30:00-05:00","event_time_end_last":"2018-01-18T11:30:00-05:00","gmt_time_start":"2018-01-18 15:30:00","gmt_time_end":"2018-01-18 16:30:00","gmt_time_end_last":"2018-01-18 16:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"213791","name":"3D Systems Packaging Research Center"},{"id":"198081","name":"Georgia Electronic Design Center (GEDC)"},{"id":"197261","name":"Institute for Electronics and Nanotechnology"},{"id":"1271","name":"NanoTECH"},{"id":"213771","name":"The Center for MEMS and Microsystems Technologies"}],"categories":[],"keywords":[{"id":"166968","name":"the Institute for Electronics and Nanotechnology"},{"id":"58001","name":"the institute for materials"},{"id":"249","name":"Biomedical Engineering"},{"id":"175382","name":"Sandia National Laboratories"},{"id":"7496","name":"microneedles"},{"id":"10454","name":"biosensors"},{"id":"107","name":"Nanotechnology"},{"id":"1588","name":"bionanotechnology"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003Eeric.vogel@mse.gatech.edu\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}