{"597429":{"#nid":"597429","#data":{"type":"event","title":"PhD Proposal by Victor Pan","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EVictor Pan\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EPhD Proposal Presentation\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDate:\u003C\/strong\u003E\u0026nbsp;Monday October 30, 2017\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETime:\u003C\/strong\u003E\u0026nbsp;8:00 AM\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ELocation:\u003C\/strong\u003E\u0026nbsp;Emory University HSRB E160\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee Members:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EYonggang Ke, PhD (Advisor, BME)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EZuhong Lu, PhD (Co-Advisor, Peking University)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EKhalid Salaita, PhD (BME, Emory University)\u003C\/p\u003E\r\n\r\n\u003Cp\u003ECheng Zhang, PhD (Peking University)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EBryan Wei, PhD (Tsinghua University)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDNA origami molecular\u0026nbsp;carriers as versatile tools for biomolecule sensing using solid state nanopores\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003ESolid-state nanopores have gained popularity in the past decade as an emerging technology for biomolecule detection. Although capable of high throughput and highly sensitive detection without expensive chemical labels or modifications, nanopores suffer from various drawbacks. As the measured output from translocation events is a simple current trace based on molecule size, any two biomolecules roughly the same size will produce indistinguishable drops in current.\u003C\/p\u003E\r\n\r\n\u003Cp\u003ENucleic acid nanotechnology has emerged as a technique to assist in nanopore mediated biomolecule detection. Nucleic acid structures, with their nanoscale programmability, can be designed to carry modifications at precise locations on the nanostructure.\u0026nbsp; Such precise control over the target capturing position allows for the design of nanostructures that can interact with biomolecules to exhibit altered translocation characteristics. This study will focus on target-induced conformational change of dynamic DNA\u0026nbsp;origami, competitive aptamer displacement, and nanostructure-nanopore interaction. By using such strategies to influence individual translocation events, the proposed work will aim to use DNA origami structures to assist in the detection and identification of various biomolecules during solid state nanopore scanning.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"DNA origami molecular carriers as versatile tools for biomolecule sensing using solid state nanopores"}],"uid":"27707","created_gmt":"2017-10-16 14:20:36","changed_gmt":"2017-10-16 14:20:36","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2017-10-23T11:19:00-04:00","event_time_end":"2017-10-23T11:19:00-04:00","event_time_end_last":"2017-10-23T11:19:00-04:00","gmt_time_start":"2017-10-23 15:19:00","gmt_time_end":"2017-10-23 15:19:00","gmt_time_end_last":"2017-10-23 15:19:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}