{"591807":{"#nid":"591807","#data":{"type":"event","title":"PhD Proposal by In-Cheol Sun","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EPhD Proposal: \u003C\/strong\u003EIn-Cheol Sun\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EDate:\u003C\/strong\u003E Friday, May 26, 2017\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETime:\u003C\/strong\u003E 11:00 am\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ELocation:\u003C\/strong\u003E Whitaker Building (BME) room 1103\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ECommittee members: \u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. Stanislav Emelianov (BME, ECE): Advisor\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. Younan Xia (BME)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. Francisco Robles (BME)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. J Brandon Dixon (ME)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. Ravi Kane (CHBE)\u003C\/p\u003E\r\n\r\n\u003Cp\u003EDr. Mostafa El-Sayed (Chemistry)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003ETitle:\u003C\/strong\u003E Gas-generating nanoparticles for the enhanced contrast of ultrasound imaging\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E Despite many advantages of ultrasound imaging, its low contrast often limits the clinical application. Even though microbubbles are commonly used for the enhance contrast, they cannot visualize extravascular diseases, because of their inability to escape from blood vessels as a result of their micron-scale sizes. For the detection of such diseases, ultrasound contrast agents should have nano-scale sizes for extravasation and simultaneously be in micron-scale for echogenicity. Therefore, novel gas-generating nanoparticles as ultrasound contrast agents are proposed. By generating gas bubbles instead of carrying it, their sizes can reduce significantly. The gas-generating nanoparticles consist of azide compounds (for gas generation) and gold nanoparticles (for carrier and photocatalyst). Triggered by laser, the gas-generating contrast agents produce gas bubbles that enhance contrast of ultrasound images. Their properties, such as size distribution, gas-generating rate, contrast enhancement, are characterized. The feasibility in medical imaging is tested through in vivo imaging of mouse models with cancer or metastatic lymph nodes. The novel contrast agents will have a major impact on the application of diagnostic ultrasound imaging.\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Gas-generating nanoparticles for the enhanced contrast of ultrasound imaging"}],"uid":"27707","created_gmt":"2017-05-16 17:45:39","changed_gmt":"2017-05-16 17:45:39","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2017-05-26T12:00:00-04:00","event_time_end":"2017-05-26T14:00:00-04:00","event_time_end_last":"2017-05-26T14:00:00-04:00","gmt_time_start":"2017-05-26 16:00:00","gmt_time_end":"2017-05-26 18:00:00","gmt_time_end_last":"2017-05-26 18:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}