{"582096":{"#nid":"582096","#data":{"type":"event","title":"GT Neuro Seminar Series","body":[{"value":"\u003Cp class=\u0022p1\u0022\u003E\u003Cstrong\u003E\u0026ldquo;Inhibitory Control of Cortical Activity \u003Ci\u003Ein vivo\u003C\/i\u003E\u0026rdquo;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p2\u0022\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p1\u0022\u003E\u003Cstrong\u003EBilal Haider, Ph.D.\u003Cbr \/\u003E\r\nAssistant Professor\u003Cbr \/\u003E\r\nWallace H. Coulter Department of Biomedical Engineering\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p2\u0022\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p1\u0022\u003EThe cerebral cortex is the largest and most complicated structure of the mammalian brain.\u0026nbsp; The cortex generates many regimes of spontaneous and sensory evoked activity.\u0026nbsp; What are the cellular and circuit mechanisms that determine these regimes? What consequences do they have for sensory processing?\u0026nbsp; And how do these mechanisms vary across behavioral states? \u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p2\u0022\u003ETo address these questions, I will present three electrophysiological studies of spiking and sub-threshold (synaptic) activity recorded from specific cortical neuron types in vivo.\u0026nbsp; First, I will show that cortical excitation and inhibition closely balance each other during ongoing spontaneous activity.\u0026nbsp; I will next show how inhibitory circuits are recruited to produce reliable and precise cortical activity during naturalistic visual stimulation.\u0026nbsp; Finally, I will show that in the awake cortex, the specific activation of inhibitory circuits dramatically sharpens the spatial and temporal resolution of visual processing.\u0026nbsp; This enhanced role of inhibition during wakefulness shapes how excitatory neuron populations relate to sensory events.\u0026nbsp; Taken together, these studies suggest that cortical inhibitory circuits play the dominant role in rapid modulation of sensory processing according to the demands of the environment and behavior.\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p2\u0022\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp class=\u0022p2\u0022\u003E\u003Cstrong\u003EBio-sketch:\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EBilal Haider is an assistant professor of biomedical engineering at Georgia Institute of Technology \u0026amp; Emory University in Atlanta.\u0026nbsp; He received his M.Phil. and Ph.D. in Neurobiology from Yale University with David McCormick.\u0026nbsp; He went on to perform postdoctoral research in visual neuroscience as an NSF International Research Fellow at University College London, UK, with Matteo Carandini and Michael Hausser.\u0026nbsp; His research focuses on synaptic and network mechanisms that allow neurons in the cerebral cortex to modulate their response properties during sensory perception and behavior.\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"\u201cInhibitory Control of Cortical Activity in vivo\u201d - Bilal Haider, Ph.D. - Georgia Tech"}],"uid":"27349","created_gmt":"2016-10-04 17:19:00","changed_gmt":"2017-04-13 21:14:27","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2016-10-24T12:00:00-04:00","event_time_end":"2016-10-24T13:00:00-04:00","event_time_end_last":"2016-10-24T13:00:00-04:00","gmt_time_start":"2016-10-24 16:00:00","gmt_time_end":"2016-10-24 17:00:00","gmt_time_end_last":"2016-10-24 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/neuralengineering.gatech.edu\/","title":"Neural Engineering Center"},{"url":"https:\/\/bme.gatech.edu\/bme\/faculty\/Bilal-Haider","title":"Haider Dept. Profile"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"248","name":"IBB"},{"id":"126591","name":"go-NeuralEngineering"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"78751","name":"Undergraduate students"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:crozell@gatech.edu\u0022\u003EChris Rozell\u003C\/a\u003E\u0026nbsp;- faculty host\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}