{"567621":{"#nid":"567621","#data":{"type":"event","title":"PhD Proposal by Bo Pang","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EPhD Proposal Presentation\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EDate:\u003C\/strong\u003E\u0026nbsp;Sept. 8th, 2016\u0026nbsp;(Thursday)\u003Cbr \/\u003E \u003Cstrong\u003ETime:\u003C\/strong\u003E\u0026nbsp;8:30 pm (Beijing) \/ 8:30 am (Atlanta)\u003Cbr \/\u003E \u003Cstrong\u003ELocation:\u0026nbsp;\u003C\/strong\u003E\u003Cbr \/\u003E New 1st COE Building, Room 210 (PKU campus at Beijing)\u003Cbr \/\u003E U.A. Whitaker Building, Room 3115 (McIntire Room, GT campus at Atlanta)\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECommittee:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EDr. Qiushi Ren (Advisor, PKU-BME)\u003C\/p\u003E\u003Cp\u003EDr. Younan Xia (Co-Advisor, GT-BME)\u003C\/p\u003E\u003Cp\u003EDr. Zhifei Dai (PKU-BME)\u003C\/p\u003E\u003Cp\u003EDr. Changhui Li (PKU-BME)\u003C\/p\u003E\u003Cp\u003EDr. Mingyuan Gao (Chinese Academy of Sciences Institute of Chemistry)\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EDevelopment of Au Nanoparticle-Based Theranostic Agents for Molecular Imaging and Cancer Therapy\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003ECancer has become a leading cause of human death and a great threat to public health worldwide. With the help of molecular imaging techniques, such as positron emission tomography and single-photon emission computed tomography, early detection of cancer could be achieved, greatly reducing the mortality for certain cancers. Nanoparticles possess remarkable physicochemical properties with a promising future in the application of cancer theranostics. Among the various kinds of nanoparticles, Au nanoparticlespossess unique properties such as bio-inertness, readily tuned optical properties, as well as easily conjugated surface in addition to the shared merits of nanoparticles.\u0026nbsp;Imaging probes and therapeutic agents are increasingly integrated with Au nanoparticles engineered with optimal sizes, shapes, and surface properties, aiming to prolong their blood circulation half-life, improve their bio-distribution as well as targeting selectivity, and ultimately reduce their side effects.\u0026nbsp;Here,\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003Ewe hypothesize that\u0026nbsp;engineered Au nanoparticles\u0026nbsp;can be preferentially delivered to cancer lesion for improved\u0026nbsp;diagnosis with molecular imaging methods, and facilitate the therapy\u0026nbsp;of cancer. In the proposed works,\u0026nbsp;we will develop Au nanoparticles with novel tripod-morphology and investigate their optical properties as well as bio-distribution profiles. Innovative radiolabeling and targeting techniques will also be developed for improved radiolabeling stability and\u0026nbsp;\u003Cem\u003Ein vivo\u003C\/em\u003E\u0026nbsp;tumor targeting capabilities. New medical isotope (Au-199) and detection methods will be introduced to Au nanoparticles for better imaging quality.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Development of Au Nanoparticle-Based Theranostic Agents for Molecular Imaging and Cancer Therapy"}],"uid":"27707","created_gmt":"2016-08-24 14:41:00","changed_gmt":"2016-10-08 02:18:40","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2016-09-08T09:30:00-04:00","event_time_end":"2016-09-08T11:00:00-04:00","event_time_end_last":"2016-09-08T11:00:00-04:00","gmt_time_start":"2016-09-08 13:30:00","gmt_time_end":"2016-09-08 15:00:00","gmt_time_end_last":"2016-09-08 15:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}