{"532661":{"#nid":"532661","#data":{"type":"news","title":"Shella Keilholz Wins Funding for Transformative Neuroscience Research","body":[{"value":"\u003Cp\u003EShella Keilholz, associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, has been selected to receive up to $40,000 from the Georgia Tech Fund for Innovation in Research and Education (GT FIRE). The program has two purposes. The first aims to facilitate planning for large extramural proposals \u2014 those that are of strategic value to the Institute. The second provides support for feasibility studies of transformative ideas in research or education.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cInnovation in research is critical for us to lead and set the science, technology and policy agenda for the United States and the world,\u201d said Steve Cross, executive vice president for research at Georgia Tech.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u201cWith our improved understanding of resting state functional magnetic resonance imaging (rs\u2010fMRI), we have come to realize that the blood oxygenation level dependent signal that is the basis for rs\u2010fMRI contains multiple components that correspond to brain function at different spatial and temporal scales,\u201d said Keilholz.\u0026nbsp; \u201cMultiple levels of information can be extracted from a single, noninvasive rs\u2010fMRI scan, providing unprecedented insight into the brain\u2019s functional architecture.\u201d\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ETo truly understand the interactions within and between processes, she wants to build a data\u2010based model that captures the complexity of the system and allows testable predictions about how network activity will respond to perturbation.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe outcome of this work will be a model based on rs\u2010fMRI data and designed to explicitly capture multiple spatial and temporal scales of activity along with a new method for characterizing the spatiotemporal evolution of brain activity. This project is an excellent fit for BRAIN Initiative proposals, which emphasize multidisciplinary, multiscale, multimodal approaches to understanding brain function. It is also in line with the joint NIH\/NSF Collaborative Research in Computational Neuroscience program. Her team, along with other researchers, will use the period of GT FIRE funding to develop and test an initial model which will serve as preliminary data for one or more proposals that can provide sustained funding.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe development of a predictive model of brain function is one of the holy grails of neuroscience. Eventually, she hopes scientists can routinely examine the network dynamics in the brain on an individual basis, partly in order to understand variations in cognitive activity, but also to find and ultimately fix deficits induced by dysfunction. They want to create models for individual patients that can be used for diagnosis, evaluation, and even treatment of psychiatric and neurological disorders.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThis project is an excellent fit with Georgia Tech\u2019s recent initiatives in high performance computing, big data, and data science. It leverages the established connection between the engineers at Georgia Tech and the clinicians at Emory facilitating translation.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EAccording to Keilholz, \u201cwe are one of the groups with the most expertise at understanding multiscale brain function, and our collaboration with experts in nonlinear dynamics and complex networks will allow us to take on a project that no other group has been able to tackle yet.\u201d\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EMedia Contacts:\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022mailto:wrich@gatech.edu\u0022\u003EWalter Rich\u003C\/a\u003E\u003Cbr \/\u003ECommunications Manager\u003Cbr \/\u003EWallace H. Coulter Department of Biomedical Engineering\u003Cbr \/\u003EGeorgia Institute of Technology\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Shella Keilholz Wins Funding for Transformative Neuroscience Research"}],"uid":"27513","created_gmt":"2016-05-04 15:31:50","changed_gmt":"2016-10-08 03:21:35","author":"Walter Rich","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2016-05-04T00:00:00-04:00","iso_date":"2016-05-04T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"532651":{"id":"532651","type":"image","title":"Shella Keilholz Wins Funding for Transformative Neuroscience Research","body":null,"created":"1462478400","gmt_created":"2016-05-05 20:00:00","changed":"1475895314","gmt_changed":"2016-10-08 02:55:14","alt":"Shella Keilholz Wins Funding for Transformative Neuroscience Research","file":{"fid":"89406","name":"0651202-p19-17-wr-ed.jpg","image_path":"\/sites\/default\/files\/images\/0651202-p19-17-wr-ed_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/0651202-p19-17-wr-ed_0.jpg","mime":"image\/jpeg","size":2814829,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/0651202-p19-17-wr-ed_0.jpg?itok=5T5mY2O2"}}},"media_ids":["532651"],"groups":[{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"1612","name":"BME"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EMedia Contacts:\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022mailto:wrich@gatech.edu\u0022\u003EWalter Rich\u003C\/a\u003E\u003Cbr \/\u003ECommunications Manager\u003Cbr \/\u003EWallace H. Coulter Department of Biomedical Engineering\u003Cbr \/\u003EGeorgia Institute of Technology\u003C\/p\u003E","format":"limited_html"}],"email":["wrich@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}