516151 event 1458632996 1492118174 "In vitro to in vivo Considerations in the Design of Synthetic-based Hydrogels for Applications in Tissue Engineering"

Stephanie J. Bryant, Ph.D.
Associate Professor
Chemical and Biological Engineering
University of Colorado Boulder

The overall research objective of this group is to combine novel cell scaffold development with mechanical cues to direct and guide tissue growth in the appropriate composition to yield a functional and integrated tissue. Tissues in the body are continually subjected to mechanical stresses. It is well known that cells detect and respond to mechanical stresses by metabolic alterations that are mediated through specific mechanotransduction pathways. Photopolymerized hydrogels offer a unique medium with which to design a wide array of scaffolds from different chemistries that exhibit a range of macroscopic properties and degradation profiles. They are interested in exploiting the hydrogel environment to study mechanotransduction pathways as well as developing novel scaffolds combined with mechanical conditioning for tissue engineering. In particular, the group is focused primarily on cartilage tissue engineering, but will soon be expanding into cardiac muscle tissue engineering.

]]> The Bioengineering Seminar Series is a joint seminar series between the Petit Institute and the Biomedical Engineering department. Seminars are held on Tuesdays or Thursdays between 11am-12pm in Petit Institute, room 1128, unless otherwise indicated.

]]> Faculty host - Johnna Temenoff, Ph.D.

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