{"41165":{"#nid":"41165","#data":{"type":"news","title":"Technology and Health: Biomedical Engineers Team with Pediatric Cardiologists and Surgeons to Improve Treatments for Pediatric Heart Patients","body":[{"value":"\u003Cp\u003E\u003C\/p\u003E\n\u003Cp\u003EGeorgia Tech has teamed with pediatric cardiologists and surgeons to develop new technologies to improve surgical planning for one of the most complex congenital heart defects in infants.\u003C\/p\u003E\n\u003Cp\u003EAlthough the normal heart has two ventricles -- lower chambers of the heart used for pumping blood through the body -- some babies are born with just one lower chamber. Considered one of the most complex congenital heart defects, single-ventricle often leads to congestive heart failure if not repaired.\u003Cbr \/\u003E\nPatients with this defect often undergo multiple surgeries to reconfigure the pulmonary and systemic systems in operations called \u0022Fontan Repairs.\u0022 Staged over several years, these surgeries are an option used for treating the single-ventricle defect. Following the procedures, a variety of outcomes from good to poor have been reported.\u003Cbr \/\u003E\nIn an effort to develop optimal surgical designs based on the child\u0027s anatomy, a team of biomedical engineers and pediatric cardiologists and surgeons announced today that they have begun developing improved technologies to assist surgeons in surgical planning of the Fontan surgery. These technologies could advance surgical methods by more specifically tailoring the procedure to the patient and possibly enhancing the patient\u0027s quality of life following the procedure.\u003Cbr \/\u003E\nThe team is funded by a $5.1 million award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).\u003Cbr \/\u003E\n\u0022Optimization of the Fontan procedure is a clinical problem,\u0022 said Ajit Yoganathan, Regents Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. \u0022Our goal is to improve the efficiency of this procedure, which is commonly utilized today.\u0022\u003Cbr \/\u003E\nThe team, led by Georgia Tech, consists of several members from three other institutions. Together they have collaborated in the development of improved imaging technologies for use in the pediatric group. The lead co-investigators and institutions involved are: Yoganathan at Georgia Tech; Shiva Sharma, a pediatric cardiologist at Sibley Heart Center at Children\u0027s Healthcare of Atlanta; Carol Lucas, a professor of biomedical engineering at the University of North Carolina at Chapel Hill (UNC); and Mark Fogel, a pediatric cardiologist at the Children\u0027s Hospital of Philadelphia\u0022\u003Cbr \/\u003E\n\u003Cstrong\u003EA Multi-Institutional Approach\u003C\/strong\u003E\u003Cbr \/\u003E\nVarious aspects of the research will be divided among the four institutions based on each institution\u0027s specialties and expertise.\u003Cbr \/\u003E\nEngineering and computational studies will be conducted primarily at Georgia Tech, while patient recruitment and MRI studies will be performed at Children\u0027s Healthcare of Atlanta, Children\u0027s Hospital of Philadelphia and UNC.\u003Cbr \/\u003E\nEngineering tools such as computational fluid dynamic studies and the development of glass models of the heart with different Fontan surgery connections will be performed at Georgia Tech and UNC. UNC will also conduct animal studies.\u003Cbr \/\u003E\nRecruitment, care and study of Fontan patients will be conducted at Children\u0027s Healthcare of Atlanta, UNC and Children\u0027s Hospital of Philadelphia. Non-invasive, 3-D MRI anatomic and flow studies on Fontan patients will be performed to serve as input data for the in-vitro and computational modeling studies.\u003Cbr \/\u003E\nCentral to the study is understanding the single-ventricle defect, its anatomy and physiology in order to improve surgical configurations and planning. The investigators are hoping their research will yield important information and better options to assist surgeons in determining the optimal surgical treatment for these young heart patients.\u003Cbr \/\u003E\n\u0022The main focus of this research is to give surgeons a tool with which to predict not only the outcome of a Fontan procedure, but also the best possible configuration,\u0022 Yoganathan said. \u0022This is done by optimization. In order to optimize the design of the Fontan procedure we know that the repair should maximize the flow of blood This is crucial in a heart that has only a single ventrical as the pumping chamber for all blood.\u0022\u003Cbr \/\u003E\nShiva Sharma, M.D., pediatric cardiologist at Children\u0027s Healthcare of Atlanta explains that currently, surgery for complex congenital heart disease is based on the surgeons experience. \u0022The utilization of computational fluid dynamics (CFD) introduces a more scientific approach using computer and graphic technology to correct heart defects For the first time, computer technology is being used to assist surgeons in correcting single ventricle defects in the most efficient way. Furthermore, this will enable customization of the Fontan repair to suit a patient\u0027s unique anatomy and physiology. This is a paradigm shift.\u0022\u003Cbr \/\u003E\nIn the U.S., two out of every 1,000 babies are born with single ventricle defects. A look at the Internet shows dozens of web sites set up by parents of infants born with a single ventricle to share updates, photos and even advice.\u003Cbr \/\u003E\nSurgical operation procedures vary for single ventricle patients, depending on factors such as age, symptom status or condition of the lung blood vessels. The most popular procedure used to correct the problem is called the total cavopulmonary connection (TCPC)\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Georgia Tech has teamed with pediatric cardiologists and surgeons to develop new technologies to improve surgical planning for one of the most complex congenital heart defects in infants.","format":"limited_html"}],"field_summary_sentence":"","uid":"15436","created_gmt":"2002-09-05 00:00:00","changed_gmt":"2016-10-08 03:02:15","author":"Automator","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2002-08-22T00:00:00-04:00","iso_date":"2002-08-22T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"41166":{"id":"41166","type":"image","title":"Fontan Surgery","body":null,"created":"1449174285","gmt_created":"2015-12-03 20:24:45","changed":"1475894366","gmt_changed":"2016-10-08 02:39:26","alt":"Fontan Surgery","file":{"fid":"190027","name":"i203c87ed5d26517ae72cb2cf39e0e2f641030725382.jpg","image_path":"\/sites\/default\/files\/images\/i203c87ed5d26517ae72cb2cf39e0e2f641030725382.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/i203c87ed5d26517ae72cb2cf39e0e2f641030725382.jpg","mime":"image\/jpeg","size":11447,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/i203c87ed5d26517ae72cb2cf39e0e2f641030725382.jpg?itok=eRsES0dy"}}},"media_ids":["41166"],"related_links":[{"url":"http:\/\/www.nhlbi.nih.gov\/index.htm","title":"The National Heart, Lung, and Blood Institute (NHL"},{"url":"http:\/\/www.bme.unc.edu\/","title":"Biomedical Engineering Department, University of N"},{"url":"http:\/\/www.chop.edu\/consumer\/index.jsp","title":"The Children\\\u0027s Hospital of Philadelphia"},{"url":"http:\/\/www.choa.org\/","title":"Children\\\u0027s Healthcare of Atlanta"},{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"}],"groups":[{"id":"1183","name":"Home"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003ELisa Grovenstein\u003C\/strong\u003E\u003Cbr \/\u003ECommunications \u0026amp; Marketing\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=lgrovenste3\u0022\u003EContact Lisa Grovenstein\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-8835\u003C\/strong\u003E","format":"limited_html"}],"email":["lisa.grovenstein@comm.gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}