{"405211":{"#nid":"405211","#data":{"type":"event","title":"PhD Defense by Chanchala Kaddi","body":[{"value":"\u003Cp align=\u0022center\u0022\u003E\u003Cstrong\u003EChanchala Kaddi\u003C\/strong\u003E\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003EPh.D. Defense Presentation\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003EFriday, May 29\u003Csup\u003Eth\u003C\/sup\u003E 2015, 2pm\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003EPetit Institute Suddath Seminar Room (IBB 1128)\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAdvisor: May D. Wang, Ph.D. \u003C\/strong\u003E(Georgia Institute of Technology)\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECommittee:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EMelissa Kemp, Ph.D.\u003C\/strong\u003E (Georgia Institute of Technology)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EDong M. Shin, M.D.\u003C\/strong\u003E (Georgia Institute of Technology, Winship Cancer Institute, Emory University)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EBrani Vidakovic, Ph.D.\u003C\/strong\u003E (Georgia Institute of Technology)\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EHoward Weiss, Ph.D.\u003C\/strong\u003E (Georgia Institute of Technology)\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\u003Cp align=\u0022center\u0022\u003E\u003Cstrong\u003EMathematical Models for Data Mining and System Dynamics to Study Head and Neck Cancer Progression and Chemoprevention\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EHead and neck squamous cell carcinoma (HNSCC) is the 6\u003Csup\u003Eth\u003C\/sup\u003E most prevalent cancer worldwide, and more than 12,000 deaths from this disease are anticipated in 2015 in the U.S. alone. The advancement of genomic, transcriptomic, and other \u2013omic data acquisition technologies has enabled deeper exploration of the molecular-level mechanisms behind HNSCC development and progression. The insights gained through data-driven analysis can lead to earlier diagnosis and better treatment strategies, and ultimately can result in better patient outcomes. However, the volume and complexity of \u2013omic data remain great challenges. \u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EThe goal of this research is to address several key challenges related to applying \u2013omic data for HNSCC research. These are: (1) the lack of modeling tools and systems for discovering biomarkers at the protein and metabolite levels; (2) the lack of effective strategies for integrating heterogeneous types of \u2013omic data for prediction; and (3) the lack of systems-level representations of biomarker knowledge for effectively predicting responses to bioactive agents. Overall, this research accelerates knowledge extraction, enables prediction using \u2013omic data for HNSCC, and delivers a suite of mathematical modeling tools for data mining and system dynamics. \u003C\/p\u003E\u003Cp\u003E \u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Mathematical Models for Data Mining and System Dynamics to Study Head and Neck Cancer Progression and Chemoprevention"}],"uid":"27707","created_gmt":"2015-05-18 08:16:06","changed_gmt":"2016-10-08 02:12:02","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-05-29T15:00:00-04:00","event_time_end":"2015-05-29T17:00:00-04:00","event_time_end_last":"2015-05-29T17:00:00-04:00","gmt_time_start":"2015-05-29 19:00:00","gmt_time_end":"2015-05-29 21:00:00","gmt_time_end_last":"2015-05-29 21:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"6178","name":"BIOE"},{"id":"1366","name":"defense"},{"id":"1808","name":"graduate students"},{"id":"913","name":"PhD"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}