{"383761":{"#nid":"383761","#data":{"type":"event","title":"Daniela Cimini, Virgina Tech","body":[{"value":"\u003Cp\u003EMechanisms and consequences of chromosome mis-segregation and aneuploidy\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EMechanisms and consequences of chromosome mis-segregation and aneuploidy\u003C\/p\u003E\u003Cp\u003EResearch in my lab focuses in two major areas: (i) the mechanics and dynamics of mitosis and the mitotic apparatus; (ii) the causes and consequences of aneuploidy in vertebrate cells.\u003C\/p\u003E\u003Cp\u003EIn this talk, I will discuss some of our findings on the mechanisms that cause aneuploidy in cancer and non-transformed cells and will show how we now use this knowledge to study how changes in chromosome number affect the fidelity of mitosis and cell proliferation in general.\u003C\/p\u003E\u003Cp\u003EI will present our recent finding that aneuploidy promotes chromosome mis-segregation and confers chromosome-specific phenotypes in human primary and cancer cells. Moreover, I will show data illustrating how aneuploidy can confer a selective advantage to cells grown under stressful environmental conditions.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Daniela Cimini, Virgina Tech"}],"uid":"27964","created_gmt":"2015-03-03 14:01:00","changed_gmt":"2017-04-13 21:19:53","author":"Jasmine Martin","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2015-04-09T12:00:00-04:00","event_time_end":"2015-04-09T12:00:00-04:00","event_time_end_last":"2015-04-09T12:00:00-04:00","gmt_time_start":"2015-04-09 16:00:00","gmt_time_end":"2015-04-09 16:00:00","gmt_time_end_last":"2015-04-09 16:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"1275","name":"School of Biological Sciences"}],"categories":[],"keywords":[{"id":"120091","name":"Daniela Cimini"},{"id":"167122","name":"Storici"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EIf you have questions about logistics or would like to set up an appointment with the speaker, please contact the School of Biology\u0027s administrative office at \u003Ca href=\u0022mailto:bio-admin@biology.gatech.edu\u0022\u003Ebio-admin@biology.gatech.edu\u003C\/a\u003E.\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}