The ACS is one of the world’s largest scientific societies, and its Fellows Program recognizes outstanding achievements in scientific research, education, leadership, and service to the chemical profession and honors a select group of members each year.

"Election as an ACS Fellow is a significant honor that recognizes not only scientific excellence but also leadership and service to the profession," said Julia Kubanek, Georgia Tech's vice president for Interdisciplinary Research. "Yuanzhi's pioneering research, her leadership within ACS and the Strategic Energy Institute, and her commitment to advancing interdisciplinary collaboration have strengthened Georgia Tech's impact in chemistry, energy, and environmental research. We are proud to celebrate this well-deserved recognition."

Tang was recognized for her contributions to environmental chemistry, biogeochemistry, and energy-related research, as well as for her leadership and service to the chemical sciences.

"Given her exceptionally energetic research program, which spans topics ranging from the basic understanding of chemical cycling on Earth to creative solutions to recover rare elements from wastes, this honor is richly deserved and completely unsurprising," said Jean Lynch-Stieglitz, chair of the School of Earth and Atmospheric Sciences. "We are lucky to have Yuanzhi as part of EAS."

As SEI executive director, Tang leads Institute-wide efforts to strengthen Georgia Tech's energy research enterprise by connecting expertise across disciplines and fostering partnerships with industry, government, and national laboratories. She also maintains an internationally recognized research program focused on understanding the chemical and biological processes that shape natural and engineered environments.

Established in 2008, the ACS Fellows Program honors a distinguished group of scientists who have made exceptional contributions to chemistry and related fields while also demonstrating dedicated service to the society. With this election, Tang joins 17 Georgia Tech ACS Fellows.

"I’m deeply honored," Tang said. "This recognition reflects the contributions of many outstanding students, postdoctoral researchers, colleagues, collaborators, and mentors throughout my career. I am grateful for the opportunity to work alongside such talented people to advance scientific discovery and build interdisciplinary partnerships that address critical energy and environmental challenges."

Founded in 1876, the American Chemical Society represents more than 170,000 members worldwide and is a leading source of scientific information through its journals, conferences, and educational programs.

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School of Electrical and Computer Engineering (ECE) Assistant Professor Amirali Aghazadeh and Ph.D. student Daniel Saeedi have developed AstroAgents, an AI system that analyzes mass spectrometry data — detailed chemical compositions from meteorites and Earth soil samples — to generate novel hypotheses about the origins of life on the planet. 

What sets AstroAgents apart is its use of agentic AI. Unlike traditional AI systems that perform fixed tasks, this agentic system is designed to pursue a scientific goal. It draws from astrobiology literature, interprets complex data, and proposes original ideas that researchers can investigate further. 

Their paper, recently featured in the journal Nature, is opening new possibilities for how scientists explore questions that have remained unanswered for decades. 

In a special Q&A, Aghazadeh and Saeedi explain how AstroAgents analyzes space chemistry, what it’s revealing about the possible origins of life on Earth, and what they hope to explore next.

READ THE Q&A

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It’s not glamorous. It’s not trendy. In fact, it’s downright grubby. But the work that a Georgia Tech researcher and his students are doing is improving campus sustainability, one pound of food waste at a time. 

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Recycled materials promise a cleaner future, but recycled content alone does not necessarily make a product sustainable. At Georgia Tech’s Daedalus Lab, assistant professor, National Science Foundation CAREER Award recipient, and Brook Byers Institute for Sustainable Systems Faculty Fellow Christos Athanasiou and postdoctoral researcher Danqi Sun are working to provide greater certainty to designers and engineers by rethinking how materials are tested for their fracture characteristics. Their article in Science Advances details a new testing protocol that reduces cost, increases speed, and simulates real-world conditions.

Materials shape nearly every part of modern life, from packaging and consumer products to bridges and medical devices. Choosing the right material involves balancing durability, cost, manufacturability, and environmental impact. Yet those decisions are not always guided by a clear understanding of how materials age and fail under real-world conditions, especially for recycled materials like plastics.

One way that materials frequently fail is by cracking. A small crack can begin almost invisibly. Over time, it can spread from regular wear and tear and exposure to common environmental factors like moisture, temperature fluctuations, or even dirt. Eventually, the crack expands, and the part fails. Engineers have studied fracture for more than a century, but connecting the science of cracking to practical decisions about sustainability remains a major challenge.

The characteristics of recycled plastics often vary from those of the same material in unrecycled, or virgin, form. Products made from recycled plastics may be sold with sustainability claims under the assumption that they will perform as if they were made with virgin material. However, premature failure requiring repair or replacement can quickly change the sustainability equation as well as the acceptance of recycled materials by manufacturers and consumers.

Beyond Conventional Fracture Testing

Materials rarely fail due to a single factor. They may be exposed to several factors simultaneously, such as mechanical loading, chemical environments, temperature changes, moisture, and time. Traditional fracture protocols test one specimen at a time under carefully controlled laboratory conditions, which bear little resemblance to the real world. To move beyond this limitation, Sun developed an in-situ, high-throughput platform capable of studying how materials degrade and fail under more realistic conditions.

The platform changes conventional fracture testing in three important ways. First, it can test multiple specimens simultaneously rather than one at a time. By monitoring samples in parallel, testing time can be reduced by more than 60%. Second, it allows materials to be tested in realistic environments. In this study, researchers examined virgin and recycled plastics in alkaline environments that resemble conditions encountered in applications like landfill liner membranes and geotextiles. Third, the platform incorporates an imaging technique known as photoelasticity, which reveals the formation of stress fields that form around the origin of a newly developing crack. This allows researchers to see cracks develop earlier than before, giving them a clearer picture of the forces that drive crack growth.

The researchers have made the technology available for licensing through Georgia Tech’s Office of Technology Licensing. “Our goal was to make fracture testing not only faster but also more informative,” Sun said. “By combining high-throughput testing, realistic environments, and full-field stress imaging, we can better understand how materials fail under conditions closer to real-world applications.”

An Honest View of Sustainability

Recycled plastics are often viewed as a greener choice. But according to the study, it’s not always so straightforward. If a recycled product fails prematurely and needs to be replaced frequently, its environmental and economic costs can increase despite its recycled content. As Athanasiou puts it, “Failing materials don’t just break products. They can break sustainability promises.”

For example, comparing virgin polyethylene terephthalate (PET) with recycled PET (rPET) in applications such as landfill geotextiles, the researchers discovered that rPET showed lower resistance to environmental stressors, particularly in alkaline conditions over a pH of 9. In this application, specifying rPET over virgin PET would likely eliminate all of the presumed economic and environmental advantages of using a recycled material.

“Recycling is essential, but recycled content alone does not tell the full story. If a material fails too soon, the environmental benefits can disappear,” Athanasiou said.

From Cracks to Circularity

For the researchers, the significance of the work extends beyond recycled plastics. The broader goal is to provide a fast, affordable, and realistic platform for evaluating the sustainability of any material choice. Because current testing protocols are costly, not widely available, and limited in the information they yield, engineers, manufacturers, and policymakers often have little choice but to continue to specify non-recycled materials because they will perform as expected. Having cheap and accurate data on recycled materials will help to accelerate their adoption because matching the engineering properties of recycled materials to their most appropriate applications will become more obvious.

The researchers also hope to expand the platform to simulate even more complex environments and apply it to a wider range of materials. Because the system generates large amounts of detailed data, it may enable opportunities to use computational modeling or artificial intelligence to digitally simulate mechanical testing, driving down costs and expanding availability even more.

The larger vision is a future in which sustainability is judged not by labels or assumptions, but by evidence for how a material performs, how long it lasts, how it fails, and what it costs society and the environment over its full lifetime.

Please visit the Daedalus Lab YouTube channel to see an explainer video about this new testing protocol: https://youtube.com/watch?v=zmRhiRIiAkQ

Read the paper here: https://www.science.org/doi/10.1126/sciadv.aeh0456

This research was supported by the National Science Foundation CAREER Award No. 2338508.

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Georgia Tech will play a key role in the newly announced Genesis Mission, a national initiative harnessing artificial intelligence (AI) to propel scientific discovery and address challenges in health, energy, manufacturing, infrastructure, and national security. The White House announced the first Genesis Mission projects on July 22 as part of a more than $5 billion investment in AI-enabled science and technology. 

The event concluded with the announcement of two rounds of seed funding, offering up to $500,000 annually for three years. The first round, announced in September 2024, provided planning grants to six teams to support their initiatives in the fall.  

Recipients of the second phase of seed funding have now been announced. This phase will provide research support in the spring, with an option for additional funding through the 2025-26 academic year. 

“This seed funding initiative by SEI and GTRI is a significant step toward advancing national security through innovative energy solutions. We believe this support will empower the funded teams to explore critical intersections between energy infrastructure and security, fostering groundbreaking advancements for a safer energy future,” said Christine Conwell, SEI’s interim executive director.  

Seven interdisciplinary projects by team members from Georgia Tech and GTRI have been selected for the second phase, also known as Category B (Table 1). 

“The seed grant initiative is supporting energy and national security collaboration among researchers from multiple units across the Georgia Tech campus,” said William H. Robinson, interim chief technology officer and deputy director for Research in GTRI’s Information and Cyber Sciences Directorate. “We are very pleased to see the teamwork of these faculty members as they address important issues facing our nation.”

A follow-up workshop will be held this summer to bring together the awardees of the seed grant program. Additionally, a lunch and learn seminar series is planned in the fall to showcase the research progress of the seed grant program. For updates, visit the Strategic Energy Institute event webpage.

The initiative included Phase 1 or Category A grants that allowed researchers up to $10,000 in seed funding to understand the viability of their research concepts. The multidisciplinary proposals that won the Category A grants include:

Project Title: Energy Infrastructure Security and Risk Assessment Through Interactive Wargaming
Primary Investigator(s)
Dimitri Mavris (School of Aerospace Engineering)
Scott Duncan (School of Aerospace Engineering)
Michael Balchanos (School of Aerospace Engineering)

Other Investigators
Adam Stulberg (School of International Affairs)
Jenna Jordan (School of International Affairs)
Margaret Kosal (School of International Affairs)

Project Title: International Workshop on Nuclear Cybersecurity: Strengthening Global Leadership and Collaboration

Primary Investigator(s)
Fan Zhang (Nuclear and Radiological Engineering)
Steve Biegalski (Nuclear and Radiological Engineering)
Valerie Thomas (School of Industrial and Systems Engineering)
Alexander Miranda (Electrial and Computer Engineering)

Other Investigators
Guenevere Chen (Electrial and Computer Engineering) (University of Texas San Antonio)

Project Title: Robust Energy Systems Planning by way of Novel Systems Engineering (RESPoNSE)

Primary Investigator(s): Comas Haynes (GTRI)

Other Investigators
Matt McDowell (School of Mechanical Engineering and School of Materials Science and Engineering)

Project Title: Shielding and Microreactor Arrangement Innovation (Samμrai)

Primary Investigator(s)
John Brittingham (GTRI)
Bojan Petrovic (School of Mechanical Engineering)

Other Investigators
Helen Works (GTRI)

Project Title: The Strategic Mineral Economy: Challenges and Opportunities for Critical Resources

Primary Investigator(s)
Bobby Harris (School of Economics)
Matthew Swarts (GTRI)

Other Investigators
Dylan Brewer (School of Economics)
Kevin Caravati (GTRI)
Laura Taylor (School of Economics)
Micah S. Ziegler (School of Chemical and Biomolecular Engineering, School of Public Policy)

Project Title: Trustworthy AI for Critical Power Grid Infrastructure Resilience
Primary Investigator(s): 
Glen Chou (School of Cybersecurity and Privacy)
Yatis Dodia (GTRI)
Saman Zonouz (School of Cybersecurity and Privacy, School of Electrical and Computer Engineering)

Phase 2 or Category B of the initiative includes up to $500,000 in seed funding to fund team research proposals, with funds likely to grow to $1.2 million in the coming years. Please note that teams must largely consist of those who participated in or expressed interest via the July workshop. 

Georgia Tech researchers and faculty are encouraged to submit the Notice of Intent for Phase 2 (Category B) submissions. While this is not a requirement of the proposal, it will provide the initiative with insights that will help with internal logistics. If you have any questions regarding the Category B Notice of Intent and the grant, please contact the Strategic Energy Institute at connect@energy.gatech.edu.

School of City and Regional Planning Assistant Professor Rounaq Basu knows it, too. So he and his students (supported by the Center for Urban Resilience and Analytics) created the Cool Routes app to help people in Atlanta find the most shaded — and most importantly, the coolest — paths if they have to walk or bike outside.

Describing Atlanta’s latest heatwave, “This is great for research, but not so great for residents,” Basu said. “I like to walk and bike everywhere, and it’s too hot. I need to know where the shaded paths are!”

The Cool Routes app currently covers 10 cities in the U.S., including Atlanta. Users choose a city from a dropdown menu, provide a trip start and destination, tell the app whether they’re walking or biking, and select route preferences. The app then generates up to three routes to the user’s destination, allowing them to compare how much cooler one route is from another. Further refinement of routes is offered after that.

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The SCC is home to seven student engineering competition teams and provides workspace, tools, and resources to help students apply classroom learning to real-world engineering challenges.

In his new role, Simmons will provide strategic leadership and operational oversight for student competition teams, facilities, staff, budgets, sponsorships, and safety programs. He also will teach and mentor students through engineering design and experiential learning courses, helping connect classroom instruction with project-based experiences.

“Richard brings a unique combination of industry experience, research leadership, and deep commitment to student success,” said Carolyn Seepersad, Eugene C. Gwaltney, Jr. School Chair. “As an accomplished engineer and a Georgia Tech alumnus, he understands the value of experiential learning and is well-positioned to lead the Student Competition Center.”

Simmons, ME 1993, joined Georgia Tech in 2016 after spending the first 20 years of his career leading research, technology, and business development initiatives in the automotive industry, energy sector, and federal government. After graduating from Tech, he earned his master’s and doctoral degrees from Purdue University and later became a licensed professional engineer.

Over the past decade, Simmons has held several leadership and research positions within Georgia Tech’s Strategic Energy Institute, including founding director of the Energy Policy and Innovation Center and, most recently, director of Research and Studies. He has also taught a variety of courses at the Woodruff School, including ME 2110, Capstone Design, Energy Systems, and Renewable Energy.

Read Full Story on the ME News Page

Blending engineering challenges, field experiences, and team-based design projects, the weeklong program in June gave students a dynamic introduction to energy, sustainability, and engineering innovation and a rare opportunity to engage directly with the technologies, infrastructure, people, and ideas that help power the world.

“Our goal is to get outside of the classroom, have fun, and demonstrate how a STEM education can literally help turn on lightbulbs,” said SEI’s director of Research and Studies, Rich Simmons, who also directs Energy Unplugged. “Through hands-on learning, field trips, and real-world experiences, these creative students are learning that everyone can play a role in our energy future. Along the way, they are gaining a deeper understanding of the tradeoffs and challenges engineers face and learning from experts about pathways to an energy career.”

Mousetrap-Powered Cars
Putting those ideas into practice from day one, the camp began with an engineering challenge in which students designed and constructed mousetrap-powered cars. Using the stored potential energy of a mousetrap spring to propel their vehicles, participants explored how energy is converted from one form to another and identified sources of friction and inefficiency that affect the distance traveled. The activity encouraged students to think like engineers, iteratively testing and refining their designs to improve results.

Engineering Optimization and Tradeoffs
Similar problem-solving skills were put to the test during an RC car optimization challenge. Equipped with a battery-powered vehicle and energy-monitoring systems, students were tasked with completing a driving course while maximizing their score by balancing speed, energy consumption, safety, and cargo capacity. Participants had the option to add weights and tennis balls to increase potential points, but doing so increased the risk of penalties from dropped cargo, missed obstacles, or vehicle rollovers. The exercise highlighted the tradeoffs engineers routinely face when optimizing systems under competing constraints.

“The overall interest in green energy among youth is increasing, so having demonstrations and experiments as well as some high-level lectures on the actual science was a great way to engage the students,” said student assistant William Nudd, a senior in mechanical engineering who assisted with the camp. “When I was in their shoes, I had never attended a physics class, so the camp was definitely getting them a step ahead and did a great job introducing and showcasing key concepts related to energy: How does my home get electricity? Where does energy come from? How do power plants operate?”

Trivia, Demos, and Scavenger Hunts
Additional activities throughout the week included energy-themed trivia competitions, a steam engine demonstration, a solar microgrid exercise, and a campus scavenger hunt. Together, they reinforced classroom concepts through interactive learning and encouraged students to connect technical principles with practical applications.

Field Trips to Power Plants
While these activities taught foundational concepts, a highlight of the camp was a series of field trips that allowed students to observe large-scale energy infrastructure in operation. Participants toured the Georgia Power McDonough-Atkinson Plant, where they learned how combined-cycle power plants generate electricity using both gas and steam turbines to improve efficiency. Students also visited the Morgan Falls hydroelectric facility, getting an up-close view of the massive generators and equipment used to convert the energy of flowing water into electricity.

Campus Tours
In addition to exploring regional energy infrastructure, students were introduced to Georgia Tech’s innovation ecosystem through visits to campus makerspaces and research facilities, including the Flowers Invention Studio and The Kendeda Building for Innovative Sustainable Design. Students explored one of the nation’s most advanced examples of sustainable building design during a guided tour of The Kendeda Building, which generates 200% of the energy it consumes. Here they learned how energy efficiency, renewable generation, and resource conservation can be integrated into the built environment.

Final Projects 
To bring together the concepts explored throughout the week, students worked in teams on a final design challenge centered around a solar-powered disaster relief trailer on loan from the Footprint Project. Equipped with photovoltaic panels and battery storage, the trailer was originally designed to provide off-grid power during emergencies. Students were challenged to identify additional uses for the system during periods when disaster response was not required. Many teams proposed sustainable food truck businesses powered by the trailer’s solar energy system.

Teams also evaluated cooking technologies such as pressure cookers and slow cookers, comparing energy consumption, power requirements, efficiency, and operating costs. Students examined how energy demand aligned with available solar generation and battery storage while conducting economic analyses to determine business viability and profitability. The project integrated engineering, economics, and sustainability principles while encouraging creative thinking and collaborative problem-solving. 

“Energy Unplugged is an inspiring demonstration of how hands-on engineering experiences can spark curiosity and passion in the next generation of STEM leaders,” said student assistant Alvaro Hucker, a senior mechanical engineering student. “Working with this group and seeing the fun they were having brought back fond memories of my own childhood. It was an amazing experience.”

Student Contributors: Alvaro Hucker, Senior, Mechanical Engineering and William Nudd, Senior, Mechanical Engineering.

Georgia’s $41 billion forest products industry needs a transformation, and a Georgia Tech research team is reimagining how pulp mills use energy and what they can make from their byproduct streams. 

The Petit Center is made possible by a transformational commitment from technology entrepreneur, philanthropist, and Georgia Tech alumnus Parker H. "Pete" Petit.

Since 1980, Petit has provided significant philanthropic support across campus, including the naming of the Parker H. Petit Institute for Bioengineering and Bioscience (IBB), one of Georgia Tech’s 11 Interdisciplinary Research Institutes. IBB is an interdisciplinary hub for transforming biological discovery into real-world health impact, bringing together engineers, scientists, and clinicians to accelerate innovations in diagnostics, therapeutics, medical devices, and biomanufacturing. With more than 300 interdisciplinary faculty researchers, 13 research centers, and 1,300 trainees making unprecedented discoveries and generating innovative technologies, IBB is a catalyst for innovative bioengineering and bioscience research. 

The success of IBB led Petit to make his latest investment, which will build on Georgia Tech’s broader commitment to medical innovation: applying engineering, computing, AI, biosciences, and systems thinking to health challenges that require more than any one field can solve. The Petit Center’s work will strengthen the tools, partnerships, and research pathways needed to help more discoveries move from the lab toward real-world patient care. 

A key goal of the Petit Center will be to use AI to build more precise models of how disease works in the body. Its first research initiative will focus on creating virtual models of human cells. Led by Jeffrey Skolnick, Regents’ Professor and Mary and Maisie Gibson Chair and GRA Eminent Scholar in Computational Systems Biology in the School of Biological Sciences, researchers will use those models to study how diseases progress and to identify treatments that may work best for individual patients. 

By modeling disease at the cellular level, researchers can test ideas faster, uncover links among different diseases, and focus on therapies most likely to help patients based on their unique biology. The work could expedite the discovery of new therapies for some of the hardest-to-treat diseases, including pancreatic cancer and glioblastoma, an aggressive form of brain cancer. 

“Medical innovation is one of the fastest-growing areas in Georgia Tech’s research, and Pete Petit’s commitment will help us further shape the future of medicine," said Ángel Cabrera, president of Georgia Tech. “This new research center will find new ways to harness the power of AI to accelerate critical medical discoveries and move them into clinical settings so patients can get the care they need. We’re deeply grateful for Pete's support, and we’re excited to get started.”

The Parker H. Petit Center for AI-Driven Health Innovation will operate under the Institute for Data Engineering and Science (IDEaS) and bring together researchers from across Georgia Tech to advance AI-driven approaches to human health. Researchers affiliated with the Petit Center will work across fields and with clinical and healthcare organizations to help close the gap between discovery and practical use. Over time and with additional investments, the Petit Center’s work will expand into areas such as cancer biomarker discovery, healthy aging, advanced cellular therapies, and AI-supported healthcare systems. 

"Georgia Tech has the expertise to redefine what is possible in healthcare through AI," said Skolnick. "By combining advanced computational methods with biological and medical insights, we can create powerful new approaches to predicting disease, identifying treatments, and improving patient outcomes." 

Petit’s commitment will support advanced computing infrastructure, graduate and postdoctoral fellowships, seed research grants, and annual programs that will bring together leading researchers from around the world working at the intersection of AI and health. 

Petit hopes this investment will inspire others to support interdisciplinary research at the Institute. "Georgia Tech has long demonstrated its ability to solve complex challenges," said Petit. "I believe artificial intelligence will fundamentally reshape healthcare, and I am excited to support a center that can help accelerate discoveries to improve and save lives." 

This transformative commitment is included in Transforming Tomorrow: The Campaign for Georgia Tech and is propelling the comprehensive campaign’s success.  

Lindsey will support BBISS’s research, education, and partnership activities across Georgia Tech and beyond. Working closely with BBISS leadership, faculty, staff, students, and external partners, he will coordinate Institute programs, support leadership operations, facilitate stakeholder engagement, and help ensure smooth day-to-day operations. 

Andrew brings more than four years of experience in project management, operations, communications, compliance oversight, and organizational improvement in higher education and nonprofit settings. Most recently, he served as project intake and communications specialist at Kennesaw State University. Before that, Lindsey spent nearly four years with the Southern States Police Benevolent Association, first as project coordinator and later as project manager.

Lindsey’s background also includes experience in higher education instruction and mentoring. As a teaching assistant with Georgia Tech’s Grand Challenges program, he worked directly with student teams tackling complex societal issues, providing guidance on research development, collaborative problem-solving, and project execution. 

He earned a B.A. in history, graduating magna cum laude from the University of Georgia in 2021, and completed a Master of Public Administration in 2025. 

“Andrew’s experience supporting complex projects, improving organizational processes, coordinating across diverse stakeholder groups, and commitment to mission-driven work make him a strong addition to the team,” said BBISS Director of Business Administration Kristina Chatfield.

That dichotomy is part of what drives the field of synthetic biology: where scientists apply engineering principles to learn from and carefully adapt nature’s biological systems to address human problems. By understanding biological systems, scientists can carefully redirect them when natural processes cause harm.

This principle has shaped my work as a biomedical engineer for over two decades. My lab studies how to program cells in order to better understand their behavior and ultimately use them as medicine. The goal is not to discard or replace nature, but to learn from biological principles and use that knowledge to responsibly help society.

Researchers announced on July 2, 2026, that they had created the first synthetic cell built from purified, nonliving components.

The lab’s cell-like system, dubbed SpudCell, raises key questions: What does it take to build a cell from scratch? If scientists assemble something that feeds, grows, copies genetic material and divides, have they created life?

How to Create Cells From Scratch

Natural cells are astonishingly complicated. Researchers want to use synthetic cells to learn more about how life works, and they are doing this by rebuilding some of life’s basic features in a simpler, more understandable form.

Earlier designs of minimal cells, used to test which components are necessary for lifelike behavior, began with existing living cells and reduced the size of their genomes. A minimal cell is useful because it is simple, but that simplicity comes at a cost. It may reveal which parts are needed for lifelike behavior, but it usually lacks the autonomy, resilience, metabolism and evolutionary capacity of natural cells.

Instead, synthetic cells are built through a bottom-up engineering approach. Scientists start with a simplified compartment – a kind of biological “box” – and ask what must be added for it to behave more like a living cell. A membrane separates the inside from the outside. Genetic material stores instructions. Molecular machinery reads those instructions to make molecules. Energy sources power reactions. Other components can allow growth, division and adaptation.

A useful way to think about synthetic cells is to compare them with technologies society already depends on. The radio wasn’t invented all at once. Engineers learned how to combine an antenna, tuner, amplifier, power source and speaker to convert invisible electromagnetic waves into sound. A car is not just a metal shell; it becomes transportation only when a frame is connected to wheels, brakes, steering, an engine, and transmission and control systems. A computer began with switches and strings of ones and zeros that could be assembled into circuits capable of storing and processing information.

Similarly, SpudCell was assembled from the bottom up with purified, nonliving parts. Researchers used lipid molecules to create a cell-like membrane, DNA molecules to store genetic instructions, purified enzymes to copy and read those instructions, and other molecular machinery to help build proteins and other molecules from small chemical building blocks, such as amino acids and nucleotides.

SpudCell is exciting scientists because it appears to bring several features of life together in one system. The researchers describe it as capable of feeding, growth, genome replication, genetically encoded division and something close to evolution. These features resemble a biological cell cycle.

Close to Life, But Not Quite

While SpudCell is an important milestone in the field, it stops short of being a fully synthetic living cell. A membrane-bound compartment containing DNA is not automatically a living cell, just as a pile of car parts is not a car.

SpudCell can carry out several life-like processes, but it is not independent. It still relies on carefully controlled laboratory conditions and on researchers to supply its molecular machinery. It doesn’t reliably pass on its genetic material or spontaneously evolve the way natural cells do.

To approach life, a synthetic cell must coordinate many processes at once. NASA describes life as a “self-sustaining chemical system capable of Darwinian evolution,” meaning it must independently use energy, copy information, grow, divide, respond to its surroundings and persist over time. Natural cells do this with extraordinary reliability because they are the products of billions of years of evolution.

SpudCell still falls short of that standard. It depends on researchers to continuously supply it with the molecular machinery to function and to physically help it divide. It also cannot reproduce indefinitely outside a carefully controlled laboratory environment. In other words, SpudCell may have been built rather than born, but it is not yet autonomous life.

That limitation does not make the achievement unimportant. In fact, it is scientifically valuable precisely because it exposes what is still missing to create life. Which parts are essential? Which processes must be coordinated? How much complexity is necessary before chemistry begins to look like biology?

Why Create Synthetic Cells?

Those questions have practical importance. Answering them can help scientists and engineers design safer biological systems for a wide range of industries.

Synthetic cells allow scientists to more cleanly test how the surrounding membrane separates the inside of a cell from its environment, how genetic instructions are read, how energy is used, and how growth and division are coordinated. These cell-like systems could eventually become simplified test beds for studying biological circuits, disease mechanisms and the origins of life.

They could also help scientists build safer systems for making medicines, fuels or materials, detecting environmental toxins, or delivering therapies without relying on fully living organisms.

More broadly, synthetic biology connects medicine and biotechnology: Viruses can be redesigned into vaccines or gene therapy, immune cells can be reprogrammed to recognize cancer, and microbes can be engineered to make useful molecules, such as insulin, or detect pollutants.

Similarly, researchers could use synthetic cells to deliver a drug only to diseased tissue, or create microbial systems that detect toxins or pathogens in water. They can also act as simplified biological factories that can make medicines without requiring a fully living organism, or as biosensors providing early warning of dangerous threats, such as bioweapons.

Creating Life Responsibly

The philosophical question “Is SpudCell alive?” may not have a simple yes or no answer.

Depending on whether your definition of life emphasizes metabolism, reproduction, evolution, autonomy or cellular organization, the boundary between living and nonliving can look very different.

Life is not defined by one property alone. Viruses contain genetic information but depend on host cells to reproduce. Mitochondria perform essential metabolism but cannot live independently outside of cells. A seed can remain dormant for years before resuming growth.

When synthetic biology is guided by a strong sense of responsibility, scientists can learn how to redirect harmful processes, build safer tools and help society. This requires not only asking whether biological systems can be built, but also whether their creation should be controlled, where they should function and what safeguards are needed.

Over the past two decades, scientists have built many kinds of biological kill switches – that is, genetic circuits that can shut down engineered cells under specific conditions. Some researchers have made cells dependent on a specific nutrient. Others have created cells that can survive only in a particular environment or activate self-destructive pathways when conditions change.

Kill switches are not magic off buttons and do not replace careful regulation, physical containment or public oversight. But they are an important example of synthetic biology’s moral compass: to not only build useful biological tools, but to build them with safety, accountability and humility in mind.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

The Parker H. Petit Institute for Bioengineering and Bioscience (IBB) is pleased to announce new leadership and membership for its External Advisory Board, which provides strategic guidance to help advance the institute's mission of accelerating interdisciplinary research and innovation. 

For years, scientists studying the human gut have relied on a material that most people would never expect: a jelly made from mouse tumors. Called Matrigel, it is used to grow tiny, patient‑derived versions of the intestine that help researchers understand disease, test new drugs, and explore future therapies. However, since this material comes from animal tissue, it’s unpredictable, difficult to control, and limits medical applications. 

Colleagues and friends remember Shelton as a dedicated mentor, collaborator, and educator, whose curiosity, generosity, and sense of humor left a lasting impression on students and peers.

“Sam exemplified the very best of Georgia Tech, and his legacy will continue to inspire generations of engineers and educators,” said Tim Lieuwen, executive vice president for Research at Georgia Tech. “I am deeply grateful for his friendship, mentorship, and leadership. My heartfelt condolences go to his family, and to the many students, colleagues, and friends whose lives he touched.”

A nationally recognized leader in energy systems, Shelton founded SEI as an interdisciplinary organization that brought together engineers, researchers, policy experts, and industry leaders to advance high-impact energy solutions. That vision remains central to SEI’s mission and continues to guide its work today.

“Sam was the quintessential engineer and innovator, whose vision was always accompanied by the development and demonstration of actual products instead of leaving them as promising concepts,” said Srinivas Garimella, Hightower Chair in the College of Engineering and professor in the George W. Woodruff School of Mechanical Engineering. “He had the rare ability to see through nebulous ideas and claims and get to the fundamental engineering truths. I am fortunate to have had the opportunity to seek his advice, which he freely gave. I will miss his friendship and counsel very much.”

During a career of more than 35 years, Shelton made lasting contributions to sustainable energy and engineering innovation. His work spanned combustion research, solar energy technologies, and offshore wind systems. He secured more than $30 million in research funding, held eight patents, founded two energy-focused companies, and helped translate research into real-world energy solutions.

In addition to his research, Shelton was deeply committed to education. During his academic career, he developed undergraduate and graduate courses in energy technology, teaching both in person and online. His Energy 101 course reached tens of thousands of learners through a massive open online course platform, covering topics such as energy supply, independence, economics, and society’s energy demands.

“When I first started at SEI in 2016, Sam and I would meet for lunch to discuss the latest research, consider how far we've come since the Carter administration, and grapple over the world’s energy problems,” said Rich Simmons, SEI’s director of Research and Studies. “Sam was genuine and objective, not working backward from a preconceived notion, but working forward with an open mind to understand, appreciate, and apply the first and second law. He was also colorful and witty! We are all privileged to pay these lessons forward to future energy students.” 

Beyond academia, Shelton’s engineering expertise reached a global stage as the designer of the Olympic torch for the 1996 Atlanta Games, an enduring symbol of innovation recognized worldwide. “The Olympics represented world peace, mankind coming together, and overcoming adversity. It was an amazing event to think about, to witness, to live through, and be a part of helping to create it,” Shelton said in a 2016 interview.

Shelton is survived by his daughters, Suzie and Stacy, three granddaughters, and a wide network of students, colleagues, and collaborators. His legacy continues through the programs he built, partnerships he fostered, and the people he helped.

A memorial service celebrating Shelton’s life will be held Aug. 1 at 1 p.m. at The 57th Fighter Group Restaurant in Atlanta. The family asks that, in lieu of flowers, memorial gifts be directed to Roll Call, Georgia Tech’s Fund for Excellence. Donations may be made at gtalumni.org/SamShelton.

Housing and transportation are top priorities for many city mayors, policymakers and public policy researchers—including Brian An, an assistant professor at Georgia Tech’s Jimmy and Rosalynn Carter School of Public Policy. But in February 2021, soon after Winter Storm Uri wreaked havoc in Texas, an eight-hour power outage at his Atlanta home became an epiphany.

“While housing stability had long been on my mind, losing power drove home the importance of another piece of urban infrastructure: reliable access to electricity,” says An, an EPIcenter faculty affiliate and co-director of the Center for Urban Research. “It sparked my interest in studying the intersection of energy and urban policy to help make cities and communities not only socially equitable but also resilient to extreme weather.”

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Superfund sites are highly contaminated areas designated by the U.S. Environmental Protection Agency (EPA) for hazardous waste cleanup. Superfund Research Centers are coordinated research programs — not physical buildings — designed to address complex environmental health problems, reduce exposure to contaminants, and improve public health. Fewer than 24 exist nationwide.

A Community Asking Questions for Decades

For generations, residents of the city of Brunswick and Glynn County have lived near former industrial facilities that produced or used chemicals such as toxaphene, PCBs, and mercury. Many have long suspected that these contaminants were affecting their health, yet lacked scientific evidence to validate their concerns.

That began to change in 2023, when Emory University researchers launched the Glynn County human exposure study at the invitation of residents. The study found elevated levels of legacy pollutants in the blood of many participants, confirming what community members had feared.

“I want more neighbors to have the opportunity to be tested and to learn about the project,” said resident Semona Holmes. “Because now more folks are saying, ‘I want to be tested.’”

Others on the coast echoed the need for continued investigation. “Exposure isn’t always uniform,” said Brunswick resident Michael Staley. “Some residents may have higher levels depending on their proximity, diet, or occupation. I hope this gives our neighbors a clearer understanding of how our communities are affected, because often regular people feel uncertain and overlooked.”

Residents have repeatedly asked for more testing, more transparency, and more opportunities to understand what is in their soil, water, and bodies. “I would like to see an expansion of the exposure study because the soil needs to be tested,” said Larry Owens, who lives near the Hercules-Pinova site, a former chemical plant that closed in 2023.

Another resident, John Freeman, emphasized the need for broad participation. “They need to make sure everybody in our neighborhood knows they are going to be doing research so that everybody will have the chance to come out and get tested and see what’s in their bodies.”

Building on Community Momentum

The new Superfund Research Center will expand this work significantly. Led by Emory University in collaboration with the Georgia Institute of Technology, the University of Georgia, Morehouse School of Medicine, Spelman College, and Texas Tech University, the center will focus on five major research areas:

• Human health research — evaluating links between chemical exposures and metabolic diseases.
• Toxicity testing — assessing how contaminants harm health.
• Environmental sampling — identifying soil, water, and other exposure pathways.
• Extreme weather modeling — studying how storms and flooding move hazardous chemicals.
• Remediation research — evaluating low‑impact cleanup strategies suitable for sensitive coastal ecosystems.

“By combining cutting-edge exposure science and health research with direct community partnerships, the center will translate complex environmental data into practical information that supports healthier decisions for families, clinicians, and policymakers,” says Dana Barr, professor of environmental health at Emory University and director of the Superfund Research Center.

Barr credited community leadership for the center's existence. “This project is a direct consequence of community support in many forms. We would not be here without your efforts, and we know what that means: We must keep community voices at the forefront of our work, and we need to deliver.”

Community Voices at the Heart of the Work

Residents say the exposure study empowered them to speak up and demand answers.

“After I learned my numbers showed contamination, I started coming to the community meetings,” said Jocelyn Farmer, a fenceline resident. “I wanted to learn more about the study and about my neighborhood.”

Another resident, Eugene Smiley, said that “everyone who lives in this neighborhood should have their blood tested. Yes, I think they should come back and give people a chance to get tested so that we all are aware of what chemicals are in our bodies.”

For many in this coastal Georgia area, the new center represents long-awaited recognition.

“We’ve been living here a long time, and we’ve been exposed to it,” said Victoria Mackey. “If this study had not happened, we would not have known. Now we have chemical awareness. There are generations that have been exposed to these chemicals. The expanded exposure study is needed.”

Community partners also see the center as a turning point.

The research involves working with Healthy Coastal Neighborhoods, a community-driven coalition working at the intersection of environmental quality and public health in Glynn County, Georgia. The coalition brings together community groups, researchers, and residents to address the toxic legacy that has affected coastal Georgia communities for decades. The coalition issued a local news release announcing the new research center on June 10.

“We are honored and truly humbled to be partners in this project,” said Jill Gambill, executive director of the CEAR Hub and senior research associate for the Institute for People and Technology at Georgia Tech-Savannah. “The residents of Glynn County have been asking hard questions about their health and environment for a long time. This center is our opportunity to put Georgia Tech's resources and expertise to work directly for the community.”

Investing in Education, Engagement, and Local Capacity

Funded at approximately $15 million over five years, the center will also support:

• Community engagement programs.
• Youth educational outreach.
• Improvements to the Healthy Coastal Neighborhoods’ Seafood Smart website.
• A community advisory group.
• Training for local healthcare providers.

“The issue of industrial contamination is inherently complex, and this Superfund Research Center offers a rare opportunity to address it from multiple angles,” says Noah Scovronick, deputy director of the center. “Just as important, the center supports community-led efforts to raise awareness and reduce exposures.”

A Model for the Nation

Although the center’s work is focused on Glynn County, its findings will have national relevance. Communities across the country face similar challenges with legacy pollutants, and the center’s research aims to provide actionable insights for reducing exposure and improving public health.

“Even after production stops, these chemicals can continue entering people’s bodies through lingering exposure pathways,” says Melanie Pearson, associate professor in the Rollins School of Public Health at Emory University. “Understanding how that happens is essential to reducing risk. Partnering with affected residents strengthens the science and ensures it leads to meaningful, real-world benefits.”

Communities across Georgia and the nation are navigating a range of economic and energy-related pressures. Gas prices, inflation, and the rapid growth of data centers are shaping the cost of goods and services, influencing everyday household financial decisions.

At the same time, ongoing geopolitical tensions are driving fluctuations in global oil markets and fuel prices. The expansion of AI data centers is also increasing demand for land, power, and water resources. And conflicts involving energy infrastructure in parts of the Middle East and Europe have affected supply stability.

Responding to these challenges requires careful analysis of emerging trends, supported by strong research in policy and economics. Faculty Affiliates of Georgia Tech’s Energy Policy and Innovation Center study these complex, interconnected issues affecting energy systems, costs, and access. They analyze emerging trends, evaluate policy options, and identify practical pathways forward.

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T1D is caused by the autoimmune destruction of insulin-producing pancreatic beta cells, requiring individuals to manage their blood glucose levels through lifelong insulin therapy. Transplanting pancreatic islets has long been investigated as a potential curative treatment, but long-lasting success in extrahepatic sites has been limited—particularly when islets are transplanted beneath the skin—due to poor blood vessel formation, immune rejection, and cellular stress following transplantation.

Vlahos’ research addresses these limitations by combining synthetic biology and tissue engineering in a new way: engineering cells to actively reshape their local environment after transplantation to make it more hospitable for the graft. Rather than relying solely on biomaterials or porous structures to support transplanted cells, the project focuses on programming the cells themselves to sense stress and respond dynamically.

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When most people think of hurricanes, they picture howling winds tearing off roofs and snapping trees. But for Ali Sarhadi, a Brook Byers Institute for Sustainable Systems (BBISS) Faculty Fellow, assistant professor in the School of Earth and Atmospheric Sciences, and director of the Climate Risk and Extreme Dynamics Lab, the real killer is often less visible. “People think that hurricanes are about wind, but sometimes that’s not the whole story,” he said. “The majority of fatalities are coming from the water, not the wind.”

Supported by two Sustainability Next Seed Grants, Sarhadi’s work draws on climate science, fluid physics, engineering, and artificial intelligence. He’s using AI-powered, physics-informed models to better anticipate water hazards that can cripple cities and power grids in both coastal and inland communities.

Rethinking Hurricane Risk

Sarhadi focuses on compound flooding, the dangerous interaction between storm surge, torrential rainfall, and river flooding that increasingly defines hurricanes. He points to Hurricane Mitch, which hit Central America in 1998, as a stark example, noting that more than 12,000 people died, “all from freshwater flooding — none from wind,” he said.

His work has shown how climate change and sea-level rise are reshaping flood risk from storms like Hurricane Sandy, which devastated New York and New Jersey in October 2012. In the current climate, a Sandy-level natural disaster has a recurrence period of roughly once every 150 years. But that is changing fast. “Because of climate change and sea-level rise, by the middle of this century, the same level of flooding is likely to occur once every 60 years. By the end of the century, that goes up to once every 30 years,” he says. “Hurricane Sandy caused about $70 billion in damage. Imagine experiencing that kind of destruction every 30 years.”

Since 1970, Sarhadi notes, damage from tropical cyclones has increased by about 380% globally, a trend driven by the combined effect of stronger storms and more people and infrastructure being located in harm’s way.

Physics-Informed AI: Street-Level Flood Warnings

While storm forecasting has improved dramatically in recent decades, Sarhadi argues, “We’re in good shape in terms of track forecasting, and we’re getting better at rapid intensification forecasting. But what is missing is the hazard part, and specifically the water part. That’s the number one killer.”

His lab is developing AI models tightly coupled with physics-based simulations to forecast hurricane-induced flooding at unprecedented resolution.

Using Hurricane Sandy as a test case, his team showed that by integrating physics-based surge and rainfall models with generative AI, they could forecast building-level flood depths three to five days before landfall. “We could predict that a storm was surge-dominant and estimate how much flooding could happen at the level of each building with an accuracy beyond 90%,” he says.   

Those extra days, and that level of granularity, could give emergency managers and local leaders the information they need to order earlier evacuations, pre-stage resources, and protect critical infrastructure. “We hope by combining AI and physics-based models we can come up with faster, more accurate modeling, first, to save lives, and then to minimize the economic damage,” Sarhadi says.

Targeting Georgia’s Coastline 

Although much of the public’s attention focuses on the Gulf Coast and megacities on the Eastern Seaboard, Georgia’s coastline is also highly vulnerable to surge and compound flooding. Sarhadi is collaborating with Georgia Tech for Georgia’s Tomorrow to model risk in places like Savannah and the surrounding coastal region. “We’re working to come up with good long-term solutions for protecting coastal communities and infrastructure,” he says.

Events like Hurricane Helene in 2024, which triggered extended blackouts in Georgia and lethal flooding in western North Carolina, underscore how far inland these risks can reach. “People think hurricanes are just a problem for coastal areas,” Sarhadi says. “But even if you are far from a coastline, you can be at risk when saturated soils, torrential rain, and river flooding combine.”

Building Climate-Resilient Power Grids and Cities

Sarhadi’s work doesn’t stop at forecasting. A central focus of his research is climate-resilient infrastructure, particularly the power grid. His team is exploring digital twin modeling — virtual replicas of energy and infrastructure systems. “When you have a digital twin of your grid, you can run that hurricane through it and identify which substations or power lines are more vulnerable,” he says, explaining that this knowledge could trigger utility crews to fix or reinforce power lines ahead of storms.

Looking decades ahead, these tools could help utilities and planners prioritize where to upgrade aging infrastructure as hurricanes intensify and water levels rise. “We know hurricanes are getting more intense, and our infrastructure is aging,” Sarhadi said. “By combining engineering, climate science, and AI, we’re trying to design better adaptation plans so our communities and power systems are more resilient in the future.”

Through a major investment from the U.S. Department of Energy (DOE), Georgia Tech is helping accelerate the development of domestic critical minerals from unconventional and secondary resources. The $7.5 million award positions the Institute to advance supply chain solutions that span resource discovery, processing, recycling, and circular materials management.

Selected by DOE’s Office of Critical Minerals and Energy Innovation, Georgia Tech will lead the Critical Minerals in the Atlantic Seaboard Plain (CM-MAP) project. The regional effort builds on DOE’s Carbon Ore, Rare Earth, and Critical Minerals (CORE-CM) initiative and will examine potential resources across the Atlantic coastal plain.

The CM-MAP project will focus on sedimentary deposits, including kaolin, bauxite, heavy mineral sands, and phosphates, as well as legacy mining residues, coal combustion byproducts, and other unconventional and secondary resources that could support future recycling and circular economy opportunities.

Drawing on existing infrastructure, regional assets, industry bases, and scientific expertise, CM-MAP will establish a regional innovation ecosystem that supports domestic critical mineral production, recycling, and advanced manufacturing, while fostering new economic opportunities throughout the Southeast.

“This is a powerful example of how Georgia Tech brings together leading research capabilities and partnerships from industry, government, nonprofits, and national labs to address complex national challenges,” said Tim Lieuwen, executive vice president for Research. “By identifying and domestically sourcing critical minerals, we are helping secure essential supply chains, while enabling the next generation of energy and materials technologies.”

The DOE award builds on a growing network of research, industry, regional, and international partnerships led by Georgia Tech to translate scientific discovery into real-world supply chain solutions, including:

• Research leadership — Founded in 2024, Georgia Tech’s Center for Critical Mineral Solutions serves as a hub for interdisciplinary research and technology development across the Institute.
• Regional partnerships —Through the Georgia Partnership for Essential Materials, a flagship regional collaboration platform, Georgia Tech, the University of Georgia, Georgia State University, and the Georgia Mining Association convene stakeholders from across the critical minerals sector. The partnership brings together industry, nonprofit organizations, regional economic development agencies, national labs, universities, and technical colleges to connect, collaborate, and stay engaged in the latest developments.
• International engagement — A U.K.-U.S. working group extends partnerships across the Southeastern United States and Southwest United Kingdom, connecting researchers, industry leaders, and government agencies working to strengthen global supply chains.
• Georgia Critical Mineral Supply Chain Manufacturing Demonstration Center — Supported through congressional funding, the center is developing capabilities and regional supply chain demonstrations that connect resource development, materials processing, recycling, and advanced manufacturing.

As part of CM-MAP, researchers will analyze materials collected from natural deposits and industrial sites throughout the Southeast to identify their critical mineral content. The resulting large datasets will be combined with artificial intelligence and machine learning approaches to better understand and predict where resources exist, optimize extraction pathways, and inform future recovery and recycling strategies.

“This project brings together a highly collaborative team from Georgia Tech, national labs, industry partners, and research institutions across the region,” said Yuanzhi Tang, the principal investigator and Georgia Power Professor in the School of Earth and Atmospheric Sciences, with a courtesy appointment in the School of Civil and Environmental Engineering.

Tang is also the founding director of the Center for Critical Mineral Solutions and executive director of the Strategic Energy Institute. 

“Through this award, we are working to build secure and resilient critical materials supply chains, from resource discovery and characterization to processing, recovery, recycling, and advanced manufacturing, while also developing the skilled workforce needed to support these emerging industries,” Tang said. “Our vision is to create a regional innovation ecosystem that embraces both unconventional resources and circular economy approaches to maximize the value of materials already in use.”

Learn more about critical materials research and workforce development efforts at Georgia Tech by visiting the Center for Critical Mineral Solutions webpage.