{"307351":{"#nid":"307351","#data":{"type":"event","title":"Immunoengineering Seminar Series","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u0022Modulating the Blood-brain Barrier at the Intracortical Tissue-electrode Interface to Evaluate Chronic\u003C\/strong\u003E\u003Cstrong\u003E\u0022\u003C\/strong\u003E\u003Cbr \/\u003E\u003Cbr \/\u003E\u003Cstrong\u003EJessica Falcone - Advisor, Ravi Bellamkonda, PhD\u003C\/strong\u003E\u003Cbr \/\u003E \u003Cbr \/\u003EIntracortical electrode recordings are a potential therapy for those living with paralysis. However, the chronic reliability of these electrodes in animals is extremely variable, which casts a shadow on chronic human use. One proposed cellular mechanism resulting in failure is the development of the astroglial scar at the electrode-tissue interface. However, there is a temporal mismatch between the stabilization of the astroglial scar (4 weeks) and cessation of neural recordings (12 weeks). Recent work from our lab has shown a correlation between electrode failure and aggravated blood-brain barrier. Here we show the blood-brain barrier healing properties of imatinib mesylate in a rat electrode-implant model. Our end goal is to modulate the blood-brain barrier and evaluate the effects of a sealed versus an opened blood-brain barrier on neural recordings.\u003C\/p\u003E\u003Cp\u003E\u003Cbr \/\u003E\u003Cstrong\u003EUpcoming Center for Immunoengineering Faculty Meetings and Seminars\u003Cbr \/\u003E\u003C\/strong\u003E\u003Cbr \/\u003E*July 11th\u003Cbr \/\u003EAugust 8th\u003Cbr \/\u003E*September 5th\u003Cbr \/\u003EOctober 3rd\u003Cbr \/\u003E*November 14th\u003Cbr \/\u003EDecember 5th\u003Cbr \/\u003E(* indicates seminar ONLY with NO 8:30 am faculty meeting)\u003C\/p\u003E\u003Cp\u003E\u003Cbr \/\u003EFaculty meetings will begin at 8:30-9:30 am on Fridays (agendas will be sent prior to meetings, including topics such as training grant planning) and be followed by the 9:30-10:30 am seminar in the Petit Institute, Room 1128, unless otherwise noted.\u003C\/p\u003E\u003Cp\u003ESeminars will feature two research presentations by graduate students and postdoctoral fellows, followed by lively discussion. The goal of this series is to enhance our immunoengineering community here at Georgia Tech and to include involvement from Emory participants at regular intervals.\u003Cbr \/\u003E\u003Cbr \/\u003EIf you have any questions or are interested in being a speaker, please contact \u003Ca href=\u0022mailto:writtase3@gatech.edu\u0022\u003EBilly Rittase\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe new Georgia Tech Center for Immunoengineering invites you to attend our Immunoengineering Trainee Seminar Series to bring together members of the bio community interested in and doing research in Immunoengineering.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Modulating the Blood-brain Barrier at the Intracortical Tissue-electrode Interface to Evaluate Chronic \u0022 - Jessica Falcone (Bellamkonda lab)"}],"uid":"27195","created_gmt":"2014-07-09 08:42:44","changed_gmt":"2017-04-13 21:22:21","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2014-07-11T10:30:00-04:00","event_time_end":"2014-07-11T11:30:00-04:00","event_time_end_last":"2014-07-11T11:30:00-04:00","gmt_time_start":"2014-07-11 14:30:00","gmt_time_end":"2014-07-11 15:30:00","gmt_time_end_last":"2014-07-11 15:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.immunoengineering.gatech.edu\/","title":"Immunoengineering website"},{"url":"http:\/\/www.ravi.gatech.edu\/","title":"Bellamkonda lab website"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"248","name":"IBB"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78751","name":"Undergraduate students"},{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:writtase3@gatech.edu\u0022\u003EBilly Ritasse\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}