Biomolecular tweezers figure

Biomolecular tweezers figure

Schematic A shows the chip layout, with circular nickel pads (blue), which can be magnetized by an external magnet flanked by interdigitated gold electrodes (red). Schematic B shows paramagnetic beads introduced to the chip surface by microfluidics and loaded onto the magnetic pads by magnetic manipulation, facilitating the formation of bead surface tethers via antibody-antigen interactions. Schematic C shows interactions probed by application of sufficient nDEP force to displace non-specifically bound beads, but not specifically bound beads. Schematic D shows how the devices are fabricated. (Image courtesy of Lizhi Cao)

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Research Horizons

Categories
Life Sciences and Biology, Research
Keywords
biomolecular tweezers, mechanical force
Status
  • Created By: John Toon
  • Workflow Status: Published
  • Created On: Dec 4, 2015 - 10:49am
  • Last Updated: Oct 7, 2016 - 10:49pm