{"242411":{"#nid":"242411","#data":{"type":"event","title":"Dynamics and Regulation of Sec-Facilitated Protein Translocation and Integral Membrane Protein Insertion","body":[{"value":"\u003Ch5\u003ESchool of Physics Soft Condensed Matter and Biophysics Series: Professor Tom Miller, Caltech\u003C\/h5\u003E\u003Cp\u003EThe Sec translocon is a central component of cellular pathways for protein translocation and membrane integration.\u0026nbsp; Using both atomistic and coarse-grained molecular simulations, we investigate the conformational landscape of the translocon and explore the role of peptide substrates in the regulation of the translocation and integration pathways.\u0026nbsp; \u0026nbsp;Implications of these results for the regulation of Sec-mediated pathways for protein translocation and membrane integration are discussed.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Dynamics and Regulation of Sec-Facilitated Protein Translocation and Integral Membrane Protein Insertion"}],"uid":"27664","created_gmt":"2013-10-03 13:32:03","changed_gmt":"2016-10-08 02:05:00","author":"Alison Morain","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2013-10-08T16:00:00-04:00","event_time_end":"2013-10-08T17:00:00-04:00","event_time_end_last":"2013-10-08T17:00:00-04:00","gmt_time_start":"2013-10-08 20:00:00","gmt_time_end":"2013-10-08 21:00:00","gmt_time_end_last":"2013-10-08 21:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"126011","name":"School of Physics"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:alison.morain@physics.gatech.edu\u0022\u003Ealison.morain@physics.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}