207241 event 1366203070 1475892201 Loice Chingozha - Advisors, Hang Lu, PhD, and Cheng Zhu, PhD

"SCOPES - Single Cell Oscillatory Platform for Extracellular Stimulation over a Large Dynamic Range"

The cellular environment that drives intracellular signaling is inherently dynamic. We have developed a SCOPES, which enables immobilization of single cells in defined compartments and subsequent exposure to precise, temporal stimuli of large dynamic range, and simultaneous imaging of intracellular signaling. We exposed cells to oscillatory stimuli and observed diverse Ca2+ levels within an isogenic cell population.

David Molony - Advisor, Don Giddens, PhD

"In-vivo Association of Wall Shear Stress and Changes in Coronary Plaque Artery Morphology"

Atherosclerotic plaques have been found to develop in low shear stress regions. The composition of these lesions alters over time and a further understanding of these morphology changes in relation to wall shear stress is required. The current study aims to relate changes in plaque morphology as measured by Virtual Histology Intravascular Ultrasound (VH-IVUS) over a 1 year period to baseline wall shear stress.

]]> The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of biotechnology related research presentations by two graduate students or post-docs of IBB and is co-sponsored by BME. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD.

]]> 65807 image 192409 image/png Manu Platt, PhD

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