{"202341":{"#nid":"202341","#data":{"type":"news","title":"New Nanotechnology Research Study Turns Brain Tumors Blue","body":[{"value":"\u003Cp\u003EResearchers from Georgia Tech and \u003Ca href=\u0022http:\/\/www.choa.org\/\u0022\u003EChildren\u0027s Healthcare of Atlanta\u003C\/a\u003E have developed a technique that assists in identifying tumors from normal brain tissue during surgery by staining tumor cells blue.\u003C\/p\u003E\u003Cp\u003EThe technique could be critically important for hospitals lacking sophisticated equipment in preserving the maximum amount of normal tissue and brain function during surgery.\u003C\/p\u003E\u003Cp\u003EPublished this week in the journal Drug Delivery and Translational Medicine, the research was led by \u003Ca href=\u0022http:\/\/www.choa.org\/Childrens-Hospital-Services\/Neurosciences\/Programs-and-Services\/Neurosurgery\/Meet-the-Team\/Barun-Brahma\u0022\u003EDr. Barun Brahma, M.D.\u003C\/a\u003E, Children\u0027s neurosurgeon and biomedical engineer, and \u003Ca href=\u0022http:\/\/www.ravi.gatech.edu\/\u0022\u003ERavi Bellamkonda\u003C\/a\u003E, the Carol Ann and David D. Flanagan Chair in Biomedical Engineering at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.\u003C\/p\u003E\u003Cp\u003EBrahma initially approached the Georgia Tech-based laboratory of Bellamkonda to see if it would be possible to manually distinguish a tumor from normal tissue during surgery without using complex equipment that might be unavailable to some health facilities.\u003C\/p\u003E\u003Cp\u003EBellamkonda\u2019s lab developed a nanocarrier made of fat that carried a clinically approved dye called Evans Blue. The team demonstrated that these nanocarriers leak out of blood vessels in the tumor margin and stain brain tumors blue. Using tumor cells injected into a rat brain, the team proved nanocarriers are able to find their way to the brain tumor and selectively dye it blue while excluding normal brain tissue.\u003C\/p\u003E\u003Cp\u003EThe findings are significant for hospitals worldwide that lack machines to help guide tumor removal, such as an intraoperative MRI machine. This new technique could help neurosurgeons remove brain tumors in children more accurately all over the world, the researchers said.\u003C\/p\u003E\u003Cp\u003EBrahma, Bellamkonda and other collaborators are developing a range of nanotechnologies designed to treat brain tumors and traumatic brain and spinal cord injuries.\u0026nbsp;Other authors on the article include researchers from the Bellamkonda lab and Phil Santangelo, assistant professor and optical imaging expert in the joint biomedical engineering department at Georgia Tech and Emory University. The collaboration embodies the power and potential of the rapidly growing partnership between Children\u0027s, Georgia Tech and Emory.\u003C\/p\u003E\u003Cp\u003EThe research effort is in collaboration with the Children\u0027s Neurosciences Center. This effort\u0026nbsp;is part of the Emory+Children\u2019s Pediatric Research Center led by Children\u2019s Healthcare of Atlanta and Emory University, including partnerships with the Georgia Institute of Technology and Morehouse School of Medicine. The research was funded by \u003Ca href=\u0022http:\/\/www.choa.org\/Childrens-Hospital-Services\/Cancer-and-Blood-Disorders\/Stop-Childhood-Cancer-Alliance\/Ians-Friends-Foundation\u0022\u003EIan\u2019s Friends Foundation\u003C\/a\u003E in Atlanta and the Georgia Cancer Coalition.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Csub\u003EChildren\u0027s Healthcare of Atlanta\u0026nbsp;\u003C\/sub\u003E\u003C\/em\u003E\u003Cbr \/\u003E\u003Csub\u003EChildren\u2019s Healthcare of Atlanta, a not-for-profit organization, is dedicated to making kids better today and healthier tomorrow. The facility\u2019s specialized care helps children get better faster and live healthier lives. Managing more than half a million patient visits annually at three hospitals and 17 neighborhood locations, Children\u2019s is the largest healthcare provider for children in Georgia and one of the largest pediatric clinical care providers in the country. Children\u2019s offers access to more than 60 pediatric specialties and programs and is ranked among the top children\u2019s hospitals in the country by U.S. News \u0026amp; World Report. With generous philanthropic and volunteer support, Children\u2019s has made an impact in the lives of children in Georgia, the United States and throughout the world. Visit \u003Ca href=\u0022http:\/\/www.choa.org\u0022\u003Ewww.choa.org\u003C\/a\u003E for more information\u003C\/sub\u003E.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EGeorgia Techn and\u0026nbsp;Children\u0027s Healthcare of Atlanta announce new technique that increases precision in brain tumor removal.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Georgia Techn and Children\u0027s Healthcare of Atlanta announce new technique that increases precision in brain tumor removal."}],"uid":"27462","created_gmt":"2013-03-27 08:35:03","changed_gmt":"2016-10-08 03:13:55","author":"Liz Klipp","boilerplate_text":"","field_publication":"","field_article_url":"","dateline":{"date":"2013-03-27T00:00:00-04:00","iso_date":"2013-03-27T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"202351":{"id":"202351","type":"image","title":"Staining Tumors Blue","body":null,"created":"1449179952","gmt_created":"2015-12-03 21:59:12","changed":"1475894856","gmt_changed":"2016-10-08 02:47:36","alt":"Staining Tumors Blue","file":{"fid":"196615","name":"blue_brain_tumor.jpg","image_path":"\/sites\/default\/files\/images\/blue_brain_tumor_0.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/images\/blue_brain_tumor_0.jpg","mime":"image\/jpeg","size":1859642,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/images\/blue_brain_tumor_0.jpg?itok=6wngvMep"}}},"media_ids":["202351"],"related_links":[{"url":"http:\/\/www.bme.gatech.edu\/","title":"Wallace H. Coulter Department of Biomedical Engineering"}],"groups":[{"id":"1214","name":"News Room"}],"categories":[{"id":"140","name":"Cancer Research"},{"id":"135","name":"Research"}],"keywords":[{"id":"62631","name":"blue staining technique"},{"id":"62621","name":"brain tumor removal"},{"id":"9721","name":"Children\u0027s Healthcare of Atlanta"},{"id":"594","name":"college of engineering"},{"id":"36141","name":"Coulter Department of Biomedical Engineering at Georgia Tech and Emory University"},{"id":"62641","name":"Dr. Barun Brahma"},{"id":"2471","name":"Ravi Bellamkonda"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EGeorgia Tech Media Relations\u003C\/strong\u003E\u003Cbr \/\u003ELaura Diamond\u003Cbr \/\u003E\u003Ca href=\u0022mailto:laura.diamond@comm.gatech.edu\u0022\u003Elaura.diamond@comm.gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-894-6016\u003Cbr \/\u003EJason Maderer\u003Cbr \/\u003E\u003Ca href=\u0022mailto:maderer@gatech.edu\u0022\u003Emaderer@gatech.edu\u003C\/a\u003E\u003Cbr \/\u003E404-660-2926\u003C\/p\u003E","format":"limited_html"}],"email":["klipp@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}