The mechanisms governing the transfer of pathogens between infected and non-infected members of a population  are critical in  shaping the outcome of an  epidemic.  This is true whether one considers human,  animal or plant populations.  Despite major efforts aimed at the mathematical modeling and mitigation of infectious diseases, the fundamental mechanisms of pathogen spreading for most infectious diseases remain poorly understood.  I present here the results of  combined theoretical and experimental studies of the role of fluid dynamics and fragmentation in disease transmission.