{"122021":{"#nid":"122021","#data":{"type":"event","title":"Prof. Nathan Gianneschi, University of California, San Diego","body":[{"value":"\u003Cp\u003EProf. Nathan Gianneschi, University of California, San Diego\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EProgramming and switching the morphology of polymeric nanoparticles with DNA, peptides and enzymes\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003ESchool of Chemistry \u0026amp; Biochemistry Special Seminar\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;Nanoscale particles capable of undergoing dramatic changes in morphology in response to stimuli are expected to have broad utility in a range of important applications including targeted drug delivery and detection strategies. To date, development of stimuli responsive systems of this type have focused on a range of triggers including pH, temperature, and to a lesser extent, the action of enzymes. Nanoparticles capable of undergoing reversible changes in morphology in a programmable manner remain relatively unexplored. The sequence selective recognition properties of DNA, and its performance as a selective substrate for enzymes make it ideal as an informational element in the synthesis of stimuli-responsive nanoscale particles. Herein, an approach to shape shifting soft polymeric materials is presented that unites the special encoding, and electrostatic properties of the DNA polymer as a construction tool and as an element in the logical manipulation of an artificial chemical system. In addition, we will describe peptide-based polymeric nanoparticle systems and their ability to undergo well-defined changes in structure and shape upon interactions with various enzymatic stimuli in complex biological environments.\u003C\/p\u003EFor more information contact \u003Ca href=\u0022http:\/\/mailto:lyon@chemistry.gatech.edu\u0022\u003EProf. Andrew Lyon\u003C\/a\u003E (404-894-4090).\u0026nbsp;","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EProf. Nathan Gianneschi, University of California, San Diego\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EProgramming and switching the morphology of polymeric nanoparticles with DNA, peptides and enzymes\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003ESchool of Chemistry \u0026amp; Biochemistry Special Seminar\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27275","created_gmt":"2012-04-04 08:48:34","changed_gmt":"2016-10-08 01:58:37","author":"Shirley Tomes","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2012-04-13T21:00:00-04:00","event_time_end":"2012-04-13T22:00:00-04:00","event_time_end_last":"2012-04-13T22:00:00-04:00","gmt_time_start":"2012-04-14 01:00:00","gmt_time_end":"2012-04-14 02:00:00","gmt_time_end_last":"2012-04-14 02:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/academicconnections.ucsd.edu\/researchscholars\/faculty_nathan_gianneschi.cfm","title":"Prof. Nathan Gianneschi, University of California, San Diego"}],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EShirley Tomes (404-894-0591) \u003Ca href=\u0022mailto:shirley.tomes@chemistry.gatech.edu\u0022\u003Eshirley.tomes@chemistry.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}