{"110641":{"#nid":"110641","#data":{"type":"event","title":"Prof. James Stambuli, The Ohio State University","body":[{"value":"\u003Cp\u003EProf. James Stambuli, The Ohio State University\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EC-H Activation Reactions Promoted by Iridium and Palladium\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003EOrganic Chemistry Seminar Series\u003C\/p\u003E\u003Cp\u003EIn recent years, the activation of C-H bonds has been transformed from an undesired step that deactivates a catalyst, to one that is synthetically useful.\u0026nbsp; Many of these transformations involve the functionalization of arenes or allylic systems via their C-H bonds.\u0026nbsp; We have developed several C-H activation reactions, but this talk will focus on the intermolecular allylic oxidation of vinylsilanes using low catalyst loadings of Pd(OAc)\u003Csub\u003E2\u003C\/sub\u003E to produce the corresponding allylic acetates.\u0026nbsp; Interestingly, \u003Cem\u003Etrans\u003C\/em\u003E-vinylsilanes are unreactive, whereas allylic oxidation reactions of \u003Cem\u003Ecis\u003C\/em\u003E-vinylsilanes proceed in good yields giving a single diastereo- and regioisomer of the branched allylic acetate \u003Cem\u003Etrans\u003C\/em\u003E-vinylsilane when benzoquinone (BQ) is employed. The use of PhI(OAc)\u003Csub\u003E2\u003C\/sub\u003E as oxidant in place of BQ provides the branched, \u003Cem\u003Ecis\u003C\/em\u003E-vinylsilane as the major product.\u0026nbsp; Intramolecular allylic etherifications of \u003Cem\u003Ecis\u003C\/em\u003E-vinylsilanes that give the corresponding vinyl tetrahydrofurans and \u2013pyrans will also be presented.\u0026nbsp; Our current efforts toward a mild, regioselective dehydrogenation of unactivated alkanes to alkenes using novel iridium complexes will also be discussed.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EFor more information contact \u003Ca href=\u0022http:\/\/mailto:stefan.france@chemistry.gatech.edu\u0022\u003EProf. Stefan France\u003C\/a\u003E (404-385-1796).\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EProf. James Stambuli, The Ohio State University\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EC-H Activation Reactions Promoted by Iridium and Palladium\u003C\/strong\u003E\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003EOrganic Chemistry Seminar Series\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"27275","created_gmt":"2012-02-20 12:06:02","changed_gmt":"2016-10-08 01:58:05","author":"Shirley Tomes","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2012-04-24T17:00:00-04:00","event_time_end":"2012-04-24T18:00:00-04:00","event_time_end_last":"2012-04-24T18:00:00-04:00","gmt_time_start":"2012-04-24 21:00:00","gmt_time_end":"2012-04-24 22:00:00","gmt_time_end_last":"2012-04-24 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.chemistry.osu.edu\/faculty\/stambuli","title":"Prof. James Stambuli, The Ohio State University"}],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EShirley Tomes (404-894-0591) \u003Ca href=\u0022mailto:shirley.tomes@chemistry.gatech.edu\u0022\u003Eshirley.tomes@chemistry.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}