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(11-0217) Prof. Scott Strobel, Yale University

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Prof. Scott Strobel, Yale University

Three views of RNA catalysis: Ribozymes, Ribosomes and Riboswitches

The catalytic mechanisms employed by RNA are chemically more diverse than initially suspected. Divalent metal ions, nucleobases, ribosyl hydroxyl groups, and even functional groups on metabolic cofactors all contribute in the various strategies employed by RNA enzymes. This catalytic breadth raises intriguing evolutionary questions about how RNA lost its biological role in some cases, but not in others, and what catalytic roles RNA might still be playing in biology.

For more information contact Prof. Adegboyega Oyelere (404-894-4047).

Status

  • Workflow Status:Published
  • Created By:Shirley Tomes
  • Created:01/18/2010
  • Modified By:Fletcher Moore
  • Modified:10/07/2016

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