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(11-0127) Prof. Indraneel Ghosh, University of Arizona
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Prof. Indraneel Ghosh, University of Arizona
When it Takes Three to Tango: Ternary Design Paradigms for Sensors and Inhibitors
The central motivation of our research program is to develop methodologies that have the potential for illuminating chemistry in a biological context. Towards his goal, I will describe new paradigms for designing supramolecular protein and peptide architectures that can serve as:
I)Turn-on split-protein sensors that are designed to respond to a variety of macromolecular targets. Our current targets include DNA, RNA, and proteins/enzymes.
II) Bivalent Inhibitors for selectively targeting protein surfaces, particularly protein kinases.
For more information contact Prof. Seth Marder (404-385-6048).
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- Workflow Status:Published
- Created By:Shirley Tomes
- Created:08/15/2010
- Modified By:Fletcher Moore
- Modified:10/07/2016
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