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Skin diseases affect half of the world’s population, but many treatments are not effective, require frequent injections, or cause significant side effects. A new skin therapy could help address those issues. Using a skin cream infused with microscopic STAR particles and a therapeutic drug, the technique could facilitate better treatment of skin diseases including psoriasis, warts, and certain types of skin cancer. The particle-infused cream, from the same research team that has developed microneedle patches for drug delivery, has been tested on skin tumors in mice.