Synthetic organelle ASC Applied Materials & Interfaces cover art

Synthetic organelle ASC Applied Materials & Interfaces cover art

An illustration of part of a synthetic organelle without a membrane. Here we see two layers that phase separate like oil and water, but both layers are water. There is no oil. Each layer contains a different solute that gives it its own chemical thermodynamics, keeping it separate from the other one. Chemical reactions cascade from one layer to the next in a chain reaction. The molecules illustrated on the outside are sugars called dextran, a solute. The gray middle layer contains an enzyme, depicted as small yellow spheres that would carry out a step in the reaction cascade. Credit: Georgia Tech (objects not to scale)

Additional Information

Groups

News Room, Research Horizons

Categories
Research, Biotechnology, Health, Bioengineering, Genetics, Chemistry and Chemical Engineering, Life Sciences and Biology
Keywords
membraneless organelle, nucleolus, cascading reactions, coacervate, metabolism, polyethylene glycol, dextran, phase separation, chemical thermodynamics, DNA transcription, colorimetric substrate, glucose oxidase, horseradish peroxidase
Status
  • Created By: Ben Brumfield
  • Workflow Status: Published
  • Created On: Sep 20, 2018 - 12:57pm
  • Last Updated: Sep 20, 2018 - 3:18pm