Simulation: DNA thicket in motion shuttles transcription factor along

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Simulation: DNA thicket in motion shuttles transcription factor along

Naturally occurring DNA is a thicket, but its high tension and constant motion make it shuttle large transcriptions factors through its dense windings to binding sites, where the factors go to work. Researchers back this hypothesis with a very large, unique simulation. Here, DNA is in gray, transcription factor LacI in green.

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College of Sciences, News Room, Research Horizons

Categories
Research, Biotechnology, Health, Bioengineering, Genetics, Computer Science/Information Technology and Security, Engineering, Life Sciences and Biology
Keywords
dna, Brownian, LacI, transcription factor, Edmond Chow, Jeffrey Skolnick, computational modeling, computational simulation
Status
  • Created By: Ben Brumfield
  • Created On: Jun 12, 2017 - 10:50am
  • Last Updated: Jun 12, 2017 - 10:50am