Tim Frank, Scientist and Sr. Technical Leader with The Dow Chemical Company presents An Overview of Separation Process Development at The Dow Chemical Company as part of ChBE's Fall Seminar Series.

ABSTRACT:
This presentation will review work processes employed at Dow for development,
implementation, and improvement of separations technology. The talk will briefly introduce the
Engineering & Process Sciences Laboratory at Dow, describe typical projects in general terms,
and then focus on several examples involving the use of glycol ethers such as 2-butoxyethanol
(commonly called ethylene glycol n-butyl ether) and 1-butoxy-2-propanol (commonly called
propylene glycol n-butyl ether). The examples will include the application of glycol ethers for
selective release of recombinant proteins from the periplasm of gram-negative bacteria for
improved recovery of enzymes and therapeutic proteins made via bacterial cultures. The use of
liquid-liquid extraction to recover glycol ether residues from aqueous effluent streams also will
be described, including application of the MOSCED activity coefficient correlation for screening
candidate solvents.

Unless otherwise noted, all seminars are held in the Molecular Science and Engineering Building in Room G011. Refreshments are served at 3:30 PM. The seminar starts promptly at 4:00 PM.