Computational Approaches to Gene Regulation Talk

Event Details
  • Date/Time:
    • Thursday September 13, 2007
      10:00 am - 12:00 am
  • Location: ISYE Executive Classroom 228
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact
Xiaoming Huo
ISyE
Contact Xiaoming Huo
404-385-0354
Summaries

Summary Sentence: Talk on Computational Approaches to Gene Regulation

Full Summary: Understanding how genes are regulated in various circumstances (e.g., heatshock, starvation, etc.) is a central problem in molecular biology. The adoption of large-scale biological data generation techniques such as the mRNA microarrays has enabled re

Jun Liu, Department of Statistics Harvard University

Computational Approaches to Gene Regulation

Understanding how genes are regulated in various circumstances (e.g.,
heatshock, starvation, etc.) is a central problem in molecular biology.
The adoption of large-scale biological data generation techniques such as
the mRNA microarrays has enabled researchers to tackle the gene regulation
problem in a global way. I will survey some computational and statistical
strategies developed by our group on how to effectively use the gene
upstream sequence information in junction with mRNA expression microarray
data to dissect the gene regulatory network. I will describe in detail a
study of RacA binding activities in Bacillus Subtilis, explaining how
statistical approaches helped the biologists discover RacA's binding
sites. I will describe a new dimension reduction technique that has been
applied successfully to our gene regulation studies and show a cute
theorem supporting the technique.

Host: Xiaoming Huo & Jeff Wu

Additional Information

In Campus Calendar
No
Groups

H. Milton Stewart School of Industrial and Systems Engineering (ISYE)

Invited Audience
No audiences were selected.
Categories
Seminar/Lecture/Colloquium
Keywords
Gene Regulation
Status
  • Created By: Mike Alberghini
  • Workflow Status: Published
  • Created On: Oct 12, 2009 - 5:22pm
  • Last Updated: Oct 7, 2016 - 9:48pm