Molecular probes fibronectin strain ECM

Molecular probes fibronectin strain ECM

Molecular probes displaying the LNLPHG and RFSAFY peptide sequences showed the greatest binding affinity to fibronectin fibers and the greatest efficiency in discriminating between relaxed and strained fibers. On extracellular matrix assembled by primary lung fibroblasts, LNLPHG preferentially attached to relaxed fibronectin fibers (top row), whereas RFSAFY bound to strained fibers (bottom row). (Scale bar: 20 microns) (Credit: Thomas Barker)

Additional Information

Groups

Research Horizons

Categories
Cancer Research, Engineering, Life Sciences and Biology, Research
Keywords
extracellular matrix, fibronectin, molecular probe, strain, Thomas Barker
Status
  • Created By: Abby Vogel Robinson
  • Workflow Status: Published
  • Created On: Dec 3, 2015 - 4:36pm
  • Last Updated: Oct 7, 2016 - 10:45pm